Symbol Name mut_rate expr_median KMT2A lysine methyltransferase 2A 17.65 8.3 NCOA3 nuclear receptor coactivator 3 17.65 7.2 CHD1 chromodomain helicase DNA binding protein 1 11.76 9.6 KMT2C lysine methyltransferase 2C 11.76 8.7 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 11.76 10.3 NSD2 nuclear receptor binding SET domain protein 2 11.76 8.5 CHD9 chromodomain helicase DNA binding protein 9 11.76 9.5 TAF1 TATA-box binding protein associated factor 1 11.76 NA KAT6B lysine acetyltransferase 6B 11.76 NA KAT6A lysine acetyltransferase 6A 11.76 NA SP140 SP140 nuclear body protein 5.88 3.9 TAF1L TATA-box binding protein associated factor 1 like 5.88 4.4 DAXX death domain associated protein 5.88 8.5 EP300 E1A binding protein p300 5.88 8.2 MGA MGA, MAX dimerization protein 5.88 8.7 NIPBL NIPBL, cohesin loading factor 5.88 8.5 CHD5 chromodomain helicase DNA binding protein 5 5.88 4.3 MSH6 mutS homolog 6 5.88 10.6 TET2 tet methylcytosine dioxygenase 2 5.88 6.9 PHIP pleckstrin homology domain interacting protein 5.88 10.2 STK31 serine/threonine kinase 31 5.88 3.9 KDM5A lysine demethylase 5A 5.88 7.5 BRD2 bromodomain containing 2 5.88 9.7 MLLT10 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 5.88 8.1 KMT2D lysine methyltransferase 2D 5.88 7.3 TRRAP transformation/transcription domain associated protein 5.88 8.3 TNRC18 trinucleotide repeat containing 18 5.88 6 LMNB2 lamin B2 5.88 7.5 NCOA1 nuclear receptor coactivator 1 5.88 8 HDAC4 histone deacetylase 4 5.88 6.3 HDAC5 histone deacetylase 5 0 6.3 TRIM28 tripartite motif containing 28 0 10.4 PRMT3 protein arginine methyltransferase 3 0 9.4 SMNDC1 survival motor neuron domain containing 1 0 10.6 IKZF1 IKAROS family zinc finger 1 0 3.9 SMYD5 SMYD family member 5 0 6.7 PRMT5 protein arginine methyltransferase 5 0 10.2 CARM1 coactivator associated arginine methyltransferase 1 0 8.8 NCOA2 nuclear receptor coactivator 2 0 5.6 KAT5 lysine acetyltransferase 5 0 7.7 CTCF CCCTC-binding factor 0 10.3 RAI1 retinoic acid induced 1 0 7.3 KDM5B lysine demethylase 5B 0 9.8 ZMYND11 zinc finger MYND-type containing 11 0 7.9 SRCAP Snf2 related CREBBP activator protein 0 5.2 RUVBL2 RuvB like AAA ATPase 2 0 11.3 BRD8 bromodomain containing 8 0 7.9 EHMT2 euchromatic histone lysine methyltransferase 2 0 7.4 MORF4L1 mortality factor 4 like 1 0 13.2 TDRKH tudor and KH domain containing 0 5.7 CHD2 chromodomain helicase DNA binding protein 2 0 7.7 CHD3 chromodomain helicase DNA binding protein 3 0 6.8 DIDO1 death inducer-obliterator 1 0 7.4 CHD4 chromodomain helicase DNA binding protein 4 0 10.1 WDR5 WD repeat domain 5 0 8 PRDM7 PR/SET domain 7 0 3.9 PRDM5 PR/SET domain 5 0 4.4 PRDM4 PR/SET domain 4 0 8.4 PSIP1 PC4 and SFRS1 interacting protein 1 0 11.2 BAZ2A bromodomain adjacent to zinc finger domain 2A 0 6.2 BAZ1A bromodomain adjacent to zinc finger domain 1A 0 10.3 SGF29 SAGA complex associated factor 29 0 8 PHF21B PHD finger protein 21B 0 6.9 CBX3 chromobox 3 0 12.6 MBD6 methyl-CpG binding domain protein 6 0 7.8 SMYD4 SET and MYND domain containing 4 0 7.3 UHRF2 ubiquitin like with PHD and ring finger domains 2 0 10.4 AEBP2 AE binding protein 2 0 6.5 TDRD9 tudor domain containing 9 0 3.8 CDYL2 chromodomain Y like 2 0 5.1 INO80C INO80 complex subunit C 0 9.5 TDRD10 tudor domain containing 10 0 4.3 SETD9 SET domain containing 9 0 7.7 NCOA7 nuclear receptor coactivator 7 0 10.4 ATF2 activating transcription factor 2 0 6.2 CREBBP CREB binding protein 0 7 PHF13 PHD finger protein 13 0 9.2 SMYD1 SET and MYND domain containing 1 0 3.8 ZCWPW2 zinc finger CW-type and PWWP domain containing 2 0 3.6 KIAA2026 KIAA2026 0 7.8 TDRD5 tudor domain containing 5 0 4.1 PWWP2B PWWP domain containing 2B 0 5.4 ASXL1 additional sex combs like 1, transcriptional regulator 0 8.5 DNMT1 DNA methyltransferase 1 0 11.9 TRDMT1 tRNA aspartic acid methyltransferase 1 0 6.2 DNMT3A DNA methyltransferase 3 alpha 0 6.8 DNMT3B DNA methyltransferase 3 beta 0 7.7 DUSP1 dual specificity phosphatase 1 0 6.7 PHC2 polyhomeotic homolog 2 0 9.7 ARID2 AT-rich interaction domain 2 0 9.3 TET3 tet methylcytosine dioxygenase 3 0 6.9 EYA4 EYA transcriptional coactivator and phosphatase 4 0 7.8 ERCC6 ERCC excision repair 6, chromatin remodeling factor 0 5.4 MECOM MDS1 and EVI1 complex locus 0 4.1 EYA1 EYA transcriptional coactivator and phosphatase 1 0 8.2 EYA2 EYA transcriptional coactivator and phosphatase 2 0 4 EYA3 EYA transcriptional coactivator and phosphatase 3 0 6.9 EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0 7.2 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0 10.3 BPTF bromodomain PHD finger transcription factor 0 9.5 JMJD1C jumonji domain containing 1C 0 8.1 ALKBH3 alkB homolog 3, alpha-ketoglutaratedependent dioxygenase 0 8.4 TDRD6 tudor domain containing 6 0 3.7 KDM1B lysine demethylase 1B 0 5.6 MTF2 metal response element binding transcription factor 2 0 9 BAHD1 bromo adjacent homology domain containing 1 0 6.2 DHX30 DExH-box helicase 30 0 9.6 SIRT2 sirtuin 2 0 7.3 SCMH1 sex comb on midleg homolog 1 (Drosophila) 0 7.6 KDM2A lysine demethylase 2A 0 7.3 KDM1A lysine demethylase 1A 0 9.9 KDM4B lysine demethylase 4B 0 7.9 NCOA6 nuclear receptor coactivator 6 0 10 SETD1B SET domain containing 1B 0 9.3 KDM4C lysine demethylase 4C 0 5.9 POGZ pogo transposable element derived with ZNF domain 0 9.9 KDM6B lysine demethylase 6B 0 6.1 RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component 0 7.6 JMJD6 arginine demethylase and lysine hydroxylase 0 6.6 JADE2 jade family PHD finger 2 0 6.1 SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0 8.6 PHF24 PHD finger protein 24 0 3.9 ADNP activity dependent neuroprotector homeobox 0 10.9 SIRT5 sirtuin 5 0 6.1 SIRT4 sirtuin 4 0 4.8 SIRT3 sirtuin 3 0 6.7 SIRT1 sirtuin 1 0 9.5 TDRD7 tudor domain containing 7 0 6.7 CBX6 chromobox 6 0 8.8 CBX5 chromobox 5 0 9.7 PHF3 PHD finger protein 3 0 8.6 BRD4 bromodomain containing 4 0 8.1 CBX7 chromobox 7 0 5.5 SUZ12 SUZ12 polycomb repressive complex 2 subunit 0 10.3 ZMYND8 zinc finger MYND-type containing 8 0 9.5 BRD1 bromodomain containing 1 0 8.5 ZBTB38 zinc finger and BTB domain containing 38 0 7.6 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 0 3.6 SHPRH SNF2 histone linker PHD RING helicase 0 9.6 SETBP1 SET binding protein 1 0 7.3 EPC2 enhancer of polycomb homolog 2 0 8.5 PHF19 PHD finger protein 19 0 8.6 KAT2A lysine acetyltransferase 2A 0 8 SND1 staphylococcal nuclease and tudor domain containing 1 0 10.1 BRPF3 bromodomain and PHD finger containing 3 0 6.2 CECR2 CECR2, histone acetyl-lysine reader 0 4.1 ATAD2 ATPase family, AAA domain containing 2 0 9.6 SETD2 SET domain containing 2 0 8 BRD7 bromodomain containing 7 0 9.2 GTF3C1 general transcription factor IIIC subunit 1 0 8.7 TFPT TCF3 fusion partner 0 7.4 HCFC2 host cell factor C2 0 6.4 DNMT3L DNA methyltransferase 3 like 0 4.3 BAZ2B bromodomain adjacent to zinc finger domain 2B 0 8.9 HDAC1 histone deacetylase 1 0 8.7 HDAC2 histone deacetylase 2 0 8.3 HDGF heparin binding growth factor 0 11.2 HELLS helicase, lymphoid-specific 0 9.2 CXXC1 CXXC finger protein 1 0 8.6 AIRE autoimmune regulator 0 4.7 PRMT2 protein arginine methyltransferase 2 0 7.6 PRMT1 protein arginine methyltransferase 1 0 12.7 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 0 3.9 IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 0 11.7 IDH2 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 0 10.7 SP110 SP110 nuclear body protein 0 5 ING1 inhibitor of growth family member 1 0 7.5 ING2 inhibitor of growth family member 2 0 8.9 JARID2 jumonji and AT-rich interaction domain containing 2 0 8.5 KMT5A lysine methyltransferase 5A 0 7.8 LBR lamin B receptor 0 11.1 LMNA lamin A/C 0 7.3 LMNB1 lamin B1 0 9.8 MBD1 methyl-CpG binding domain protein 1 0 7 MEN1 menin 1 0 8.6 MGMT O-6-methylguanine-DNA methyltransferase 0 8.2 MLLT6 MLLT6, PHD finger domain containing 0 7.9 RERE arginine-glutamic acid dipeptide repeats 0 5.1 PHF20L1 PHD finger protein 20-like 1 0 7.4 KMT5B lysine methyltransferase 5B 0 9.4 PCNA proliferating cell nuclear antigen 0 12.8 PHF11 PHD finger protein 11 0 4.5 ING4 inhibitor of growth family member 4 0 8 PHF20 PHD finger protein 20 0 8.9 PHF21A PHD finger protein 21A 0 7.6 ACTL6B actin like 6B 0 7.8 SFMBT1 Scm-like with four mbt domains 1 0 4.9 PHF7 PHD finger protein 7 0 4.6 SIRT7 sirtuin 7 0 8.2 SIRT6 sirtuin 6 0 5.9 HDAC7 histone deacetylase 7 0 6.2 TRIM33 tripartite motif containing 33 0 9.2 ARID4B AT-rich interaction domain 4B 0 9 RSF1 remodeling and spacing factor 1 0 8.5 KDM3B lysine demethylase 3B 0 9.5 PHF1 PHD finger protein 1 0 8 PHF2 PHD finger protein 2 0 8.8 MBD3 methyl-CpG binding domain protein 3 0 8.5 BRWD1 bromodomain and WD repeat domain containing 1 0 6.3 SETD4 SET domain containing 4 0 7.2 POLE3 DNA polymerase epsilon 3, accessory subunit 0 10.5 CHRAC1 chromatin accessibility complex 1 0 7.2 ATAD2B ATPase family, AAA domain containing 2B 0 7 PRMT7 protein arginine methyltransferase 7 0 6.9 ING3 inhibitor of growth family member 3 0 7.7 INO80 INO80 complex subunit 0 7.6 MPHOSPH8 M-phase phosphoprotein 8 0 8.9 MBTD1 mbt domain containing 1 0 9.4 GATAD2A GATA zinc finger domain containing 2A 0 8.1 NSD3 nuclear receptor binding SET domain protein 3 0 7.6 ZCWPW1 zinc finger CW-type and PWWP domain containing 1 0 5.2 ELP3 elongator acetyltransferase complex subunit 3 0 9.2 UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0 9.8 PRMT6 protein arginine methyltransferase 6 0 8.4 PBRM1 polybromo 1 0 8.4 SETD5 SET domain containing 5 0 8.1 ASXL2 additional sex combs like 2, transcriptional regulator 0 6.4 MRGBP MRG domain binding protein 0 8.7 PHF10 PHD finger protein 10 0 8.9 CHD7 chromodomain helicase DNA binding protein 7 0 8.8 PPP4R3A protein phosphatase 4 regulatory subunit 3A 0 8.2 KDM4D lysine demethylase 4D 0 5 ATF7IP activating transcription factor 7 interacting protein 0 9.2 MBD5 methyl-CpG binding domain protein 5 0 6.3 KDM3A lysine demethylase 3A 0 10 ASH1L ASH1 like histone lysine methyltransferase 0 9.9 KMT2E lysine methyltransferase 2E 0 9.6 DMAP1 DNA methyltransferase 1 associated protein 1 0 7.4 RNF17 ring finger protein 17 0 3.9 TDRD1 tudor domain containing 1 0 3.4 PRMT8 protein arginine methyltransferase 8 0 4.2 SMYD2 SET and MYND domain containing 2 0 10.4 PRDM8 PR/SET domain 8 0 3.9 PRDM9 PR/SET domain 9 0 3.5 PRDM10 PR/SET domain 10 0 6.5 PRDM11 PR/SET domain 11 0 4.1 INTS12 integrator complex subunit 12 0 9.5 PPP4R3B protein phosphatase 4 regulatory subunit 3B 0 8.7 CBX8 chromobox 8 0 5.9 AICDA activation induced cytidine deaminase 0 3.7 GATAD2B GATA zinc finger domain containing 2B 0 8 ARID1B AT-rich interaction domain 1B 0 7.5 MTA3 metastasis associated 1 family member 3 0 7.9 BAHCC1 BAH domain and coiled-coil containing 1 0 4.8 EP400 E1A binding protein p400 0 7.9 PHF12 PHD finger protein 12 0 5.7 ZBTB4 zinc finger and BTB domain containing 4 0 7.8 PHRF1 PHD and ring finger domains 1 0 6.9 CHD8 chromodomain helicase DNA binding protein 8 0 8.3 SFMBT2 Scm-like with four mbt domains 2 0 4.5 NCOA5 nuclear receptor coactivator 5 0 6.7 RAG2 recombination activating 2 0 3.5 ACTA1 actin, alpha 1, skeletal muscle 0 4 ARID4A AT-rich interaction domain 4A 0 6.8 RBBP4 RB binding protein 4, chromatin remodeling factor 0 8.4 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 0 7.6 PRDM12 PR/SET domain 12 0 4 PRDM13 PR/SET domain 13 0 4.3 DPF2 double PHD fingers 2 0 9.2 RING1 ring finger protein 1 0 9.3 RNF2 ring finger protein 2 0 7.8 ACTB actin beta 0 12.7 ATXN7 ataxin 7 0 6.2 PRDM16 PR/SET domain 16 0 3.6 PRDM15 PR/SET domain 15 0 4.8 PRDM14 PR/SET domain 14 0 5.1 PRDM1 PR/SET domain 1 0 4.6 SET SET nuclear proto-oncogene 0 12.5 SETMAR SET domain and mariner transposase fusion gene 0 9.4 NSD1 nuclear receptor binding SET domain protein 1 0 5.6 ACTR6 ARP6 actin related protein 6 homolog 0 10.3 SMYD3 SET and MYND domain containing 3 0 9.4 MEAF6 MYST/Esa1 associated factor 6 0 6.6 SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0 7 BRD9 bromodomain containing 9 0 8 SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0 9.6 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 0 9.8 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 0 8.7 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0 7 SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0 7.8 SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0 7.9 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0 11.8 SP100 SP100 nuclear antigen 0 4.9 BRDT bromodomain testis associated 0 3.8 HNF1A HNF1 homeobox A 0 4.1 TCF19 transcription factor 19 0 6.8 TCF20 transcription factor 20 0 8.5 VPS72 vacuolar protein sorting 72 homolog 0 10.8 TP53BP1 tumor protein p53 binding protein 1 0 7.2 YY1 YY1 transcription factor 0 11.6 PCGF2 polycomb group ring finger 2 0 7.3 ZMYM2 zinc finger MYM-type containing 2 0 6.3 PRDM2 PR/SET domain 2 0 6.2 BRPF1 bromodomain and PHD finger containing 1 0 8.2 FTO FTO, alpha-ketoglutarate dependent dioxygenase 0 9.6 PHF23 PHD finger protein 23 0 8.8 RIOX1 ribosomal oxygenase 1 0 8.1 TBL1XR1 transducin beta like 1 X-linked receptor 1 0 9.4 SUV39H2 suppressor of variegation 3-9 homolog 2 0 7.8 EHMT1 euchromatic histone lysine methyltransferase 1 0 7.2 ZMYM1 zinc finger MYM-type containing 1 0 7 KDM8 lysine demethylase 8 0 4.4 HDAC11 histone deacetylase 11 0 5.7 ACTR5 ARP5 actin related protein 5 homolog 0 7 SETD6 SET domain containing 6 0 8.6 JADE1 jade family PHD finger 1 0 8.3 PHC3 polyhomeotic homolog 3 0 7.1 BRD3 bromodomain containing 3 0 10.2 TET1 tet methylcytosine dioxygenase 1 0 9.3 EPC1 enhancer of polycomb homolog 1 0 5 NCOA4 nuclear receptor coactivator 4 0 12 ASXL3 additional sex combs like 3, transcriptional regulator 0 5.2 KDM7A lysine demethylase 7A 0 5.9 SETD7 SET domain containing lysine methyltransferase 7 0 10 FXR1 FMR1 autosomal homolog 1 0 7.7 YEATS4 YEATS domain containing 4 0 8.2 TDRD3 tudor domain containing 3 0 8.3 AKAP1 A-kinase anchoring protein 1 0 9.7 DPF1 double PHD fingers 1 0 6.8 ARID1A AT-rich interaction domain 1A 0 8.7 BAP1 BRCA1 associated protein 1 0 7.6 L3MBTL2 L3MBTL2 polycomb repressive complex 1 subunit 0 7.3 SETDB2 SET domain bifurcated 2 0 5.5 TAF3 TATA-box binding protein associated factor 3 0 7.1 HDAC10 histone deacetylase 10 0 4.7 CHD6 chromodomain helicase DNA binding protein 6 0 5.3 SETD3 SET domain containing 3 0 7.5 ING5 inhibitor of growth family member 5 0 7.1 RAD54L RAD54 like (S. cerevisiae) 0 7.7 DOT1L DOT1 like histone lysine methyltransferase 0 6.3 L3MBTL3 l(3)mbt-like 3 (Drosophila) 0 6.8 TTF2 transcription termination factor 2 0 8.4 ZGPAT zinc finger CCCH-type and G-patch domain containing 0 7 GLYR1 glyoxylate reductase 1 homolog 0 6.5 KDM2B lysine demethylase 2B 0 9.6 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0 10.3 CBX2 chromobox 2 0 6.3 PCGF1 polycomb group ring finger 1 0 9.8 KMT5C lysine methyltransferase 5C 0 5.5 RIOX2 ribosomal oxygenase 2 0 8.3 MUM1 melanoma associated antigen (mutated) 1 0 7.5 HAT1 histone acetyltransferase 1 0 10.7 CBX4 chromobox 4 0 8 RUVBL1 RuvB like AAA ATPase 1 0 10.6 ACTL6A actin like 6A 0 10.4 EED embryonic ectoderm development 0 5.9 TRIM24 tripartite motif containing 24 0 10.8 HDAC3 histone deacetylase 3 0 8.7 ALKBH1 alkB homolog 1, histone H2A dioxygenase 0 7.4 KAT2B lysine acetyltransferase 2B 0 6.3 MBD4 methyl-CpG binding domain 4, DNA glycosylase 0 9.4 MBD2 methyl-CpG binding domain protein 2 0 4.2 BAZ1B bromodomain adjacent to zinc finger domain 1B 0 8.7 BTAF1 B-TFIID TATA-box binding protein associated factor 1 0 9.7 ASH2L ASH2 like histone lysine methyltransferase complex subunit 0 10.2 PYGO2 pygopus family PHD finger 2 0 7.3 PRMT9 protein arginine methyltransferase 9 0 8.2 MTA1 metastasis associated 1 0 7.4 L3MBTL4 l(3)mbt-like 4 (Drosophila) 0 4.5 ZMYM4 zinc finger MYM-type containing 4 0 8.9 ZMYM6 zinc finger MYM-type containing 6 0 6.3 ZMYM5 zinc finger MYM-type containing 5 0 6.4 MTA2 metastasis associated 1 family member 2 0 4.9 GLYATL1 glycine-N-acyltransferase like 1 0 3.8 PRDM6 PR/SET domain 6 0 4.7 GTF3C4 general transcription factor IIIC subunit 4 0 9.2 SP140L SP140 nuclear body protein like 0 4.8 ACTR8 ARP8 actin related protein 8 homolog 0 7 CDYL chromodomain Y like 0 8.3 FXR2 FMR1 autosomal homolog 2 0 7.5 CLOCK clock circadian regulator 0 8.6 NCOR1 nuclear receptor corepressor 1 0 8 PHF14 PHD finger protein 14 0 7.9 KDM4A lysine demethylase 4A 0 7.4 HDAC9 histone deacetylase 9 0 5.5 SETD1A SET domain containing 1A 0 5.7 KMT2B lysine methyltransferase 2B 0 5.2 TRIM66 tripartite motif containing 66 0 5.3 SETDB1 SET domain bifurcated 1 0 7.7