Symbol Name mut_rate expr_median NCOA3 nuclear receptor coactivator 3 25.29 7.9 KMT2C lysine methyltransferase 2C 17.24 8.1 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 16.09 9.2 TRRAP transformation/transcription domain associated protein 12.64 8.3 CHD9 chromodomain helicase DNA binding protein 9 12.07 8.8 MGA MGA, MAX dimerization protein 11.49 8.3 ARID1A AT-rich interaction domain 1A 11.49 8.6 TAF1L TATA-box binding protein associated factor 1 like 10.34 4.4 CREBBP CREB binding protein 9.2 6.6 EP300 E1A binding protein p300 9.2 8 NIPBL NIPBL, cohesin loading factor 9.2 8.6 KAT6B lysine acetyltransferase 6B 8.62 NA CHD5 chromodomain helicase DNA binding protein 5 8.05 4.3 CHD8 chromodomain helicase DNA binding protein 8 8.05 8.2 ATRX ATRX, chromatin remodeler 8.05 NA KDM5A lysine demethylase 5A 7.47 7 BRDT bromodomain testis associated 7.47 3.8 NCOA1 nuclear receptor coactivator 1 6.9 8.1 KMT2A lysine methyltransferase 2A 6.32 7.9 EP400 E1A binding protein p400 6.32 7.6 NCOA2 nuclear receptor coactivator 2 5.75 5.2 CHD1 chromodomain helicase DNA binding protein 1 5.75 9.25 ERCC6 ERCC excision repair 6, chromatin remodeling factor 5.75 5.3 PHF3 PHD finger protein 3 5.75 8.5 NSD3 nuclear receptor binding SET domain protein 3 5.75 7.2 NSD1 nuclear receptor binding SET domain protein 1 5.75 5.7 TET1 tet methylcytosine dioxygenase 1 5.75 6.55 KAT6A lysine acetyltransferase 6A 5.75 NA RAI1 retinoic acid induced 1 5.17 7.2 ATF2 activating transcription factor 2 4.6 6.4 HDAC2 histone deacetylase 2 4.6 7.2 PHIP pleckstrin homology domain interacting protein 4.6 9.6 PRDM16 PR/SET domain 16 4.6 3.7 TP53BP1 tumor protein p53 binding protein 1 4.6 6.8 TAF1 TATA-box binding protein associated factor 1 4.6 NA IKZF1 IKAROS family zinc finger 1 4.02 3.9 SP140 SP140 nuclear body protein 4.02 4 TRIM33 tripartite motif containing 33 4.02 8.9 HDAC4 histone deacetylase 4 4.02 6.05 DAXX death domain associated protein 3.45 8.1 SUZ12 SUZ12 polycomb repressive complex 2 subunit 3.45 10.6 MSH6 mutS homolog 6 3.45 10.15 STK31 serine/threonine kinase 31 3.45 4.4 TNRC18 trinucleotide repeat containing 18 3.45 6.1 SETDB1 SET domain bifurcated 1 3.45 6.8 KDM6A lysine demethylase 6A 3.45 NA DNMT1 DNA methyltransferase 1 2.87 11.6 ING1 inhibitor of growth family member 1 2.87 7.4 NSD2 nuclear receptor binding SET domain protein 2 2.87 8.1 ZMYM2 zinc finger MYM-type containing 2 2.87 5.6 MLLT10 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 2.87 7.4 KAT7 lysine acetyltransferase 7 2.87 NA TRIM28 tripartite motif containing 28 2.3 10.3 TET2 tet methylcytosine dioxygenase 2 2.3 6.1 HNF1A HNF1 homeobox A 2.3 4.3 NCOA4 nuclear receptor coactivator 4 2.3 11.7 BAP1 BRCA1 associated protein 1 2.3 7.1 HDAC3 histone deacetylase 3 2.3 8.8 PSIP1 PC4 and SFRS1 interacting protein 1 1.72 9.7 DNMT3B DNA methyltransferase 3 beta 1.72 7.85 SIRT1 sirtuin 1 1.72 8.7 BRD2 bromodomain containing 2 1.72 10 BRD3 bromodomain containing 3 1.72 9.1 LMNB2 lamin B2 1.72 7.6 TRIM24 tripartite motif containing 24 1.72 9.5 HDAC6 histone deacetylase 6 1.72 NA BRD4 bromodomain containing 4 1.15 8 SP110 SP110 nuclear body protein 1.15 6.8 LMNA lamin A/C 1.15 9.2 LMNB1 lamin B1 1.15 9.9 MEN1 menin 1 1.15 8.5 MLLT6 MLLT6, PHD finger domain containing 1.15 7.6 SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.15 6.9 ASH2L ASH2 like histone lysine methyltransferase complex subunit 1.15 10 HDAC8 histone deacetylase 8 1.15 NA BAG6 BCL2 associated athanogene 6 1.15 NA DUSP1 dual specificity phosphatase 1 0.57 7.3 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.57 9.9 BPTF bromodomain PHD finger transcription factor 0.57 8.5 TFPT TCF3 fusion partner 0.57 7.5 IDH2 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 0.57 9.6 JARID2 jumonji and AT-rich interaction domain containing 2 0.57 7.6 SET SET nuclear proto-oncogene 0.57 12.2 SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.57 9.1 KMT2D lysine methyltransferase 2D 0.57 6.95 SP140L SP140 nuclear body protein like 0.57 8 TDG thymine DNA glycosylase 0.57 NA ZBTB33 zinc finger and BTB domain containing 33 0.57 NA BMI1 BMI1 proto-oncogene, polycomb ring finger 0.57 NA HDAC5 histone deacetylase 5 0 5.5 PRMT3 protein arginine methyltransferase 3 0 9.7 SMNDC1 survival motor neuron domain containing 1 0 10.4 SMYD5 SMYD family member 5 0 6.8 PRMT5 protein arginine methyltransferase 5 0 10.55 CARM1 coactivator associated arginine methyltransferase 1 0 8.3 KAT5 lysine acetyltransferase 5 0 8 CTCF CCCTC-binding factor 0 9.9 KDM5B lysine demethylase 5B 0 9 ZMYND11 zinc finger MYND-type containing 11 0 7.65 SRCAP Snf2 related CREBBP activator protein 0 5.2 RUVBL2 RuvB like AAA ATPase 2 0 11.4 BRD8 bromodomain containing 8 0 7.8 EHMT2 euchromatic histone lysine methyltransferase 2 0 7.1 MORF4L1 mortality factor 4 like 1 0 12.8 TDRKH tudor and KH domain containing 0 5.4 CHD2 chromodomain helicase DNA binding protein 2 0 7.9 CHD3 chromodomain helicase DNA binding protein 3 0 6.8 DIDO1 death inducer-obliterator 1 0 7.3 CHD4 chromodomain helicase DNA binding protein 4 0 9.5 WDR5 WD repeat domain 5 0 8.1 PRDM7 PR/SET domain 7 0 4.1 PRDM5 PR/SET domain 5 0 4.2 PRDM4 PR/SET domain 4 0 8.05 BAZ2A bromodomain adjacent to zinc finger domain 2A 0 6.4 BAZ1A bromodomain adjacent to zinc finger domain 1A 0 9.75 SGF29 SAGA complex associated factor 29 0 8 PHF21B PHD finger protein 21B 0 3.9 CBX3 chromobox 3 0 12.3 MBD6 methyl-CpG binding domain protein 6 0 7.7 SMYD4 SET and MYND domain containing 4 0 7.5 UHRF2 ubiquitin like with PHD and ring finger domains 2 0 9.9 AEBP2 AE binding protein 2 0 6.5 TDRD9 tudor domain containing 9 0 3.9 CDYL2 chromodomain Y like 2 0 5.1 INO80C INO80 complex subunit C 0 9.45 TDRD10 tudor domain containing 10 0 4.3 SETD9 SET domain containing 9 0 7.8 NCOA7 nuclear receptor coactivator 7 0 10.2 PHF13 PHD finger protein 13 0 9.4 SMYD1 SET and MYND domain containing 1 0 3.8 ZCWPW2 zinc finger CW-type and PWWP domain containing 2 0 3.5 KIAA2026 KIAA2026 0 7.3 TDRD5 tudor domain containing 5 0 4.2 PWWP2B PWWP domain containing 2B 0 5.4 ASXL1 additional sex combs like 1, transcriptional regulator 0 8.3 TRDMT1 tRNA aspartic acid methyltransferase 1 0 5.8 DNMT3A DNA methyltransferase 3 alpha 0 6 PHC2 polyhomeotic homolog 2 0 10.1 ARID2 AT-rich interaction domain 2 0 8.4 TET3 tet methylcytosine dioxygenase 3 0 6.7 EYA4 EYA transcriptional coactivator and phosphatase 4 0 5.35 MECOM MDS1 and EVI1 complex locus 0 6.9 EYA1 EYA transcriptional coactivator and phosphatase 1 0 4.4 EYA2 EYA transcriptional coactivator and phosphatase 2 0 4.4 EYA3 EYA transcriptional coactivator and phosphatase 3 0 6.8 EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0 7 JMJD1C jumonji domain containing 1C 0 7.8 ALKBH3 alkB homolog 3, alpha-ketoglutaratedependent dioxygenase 0 8.7 TDRD6 tudor domain containing 6 0 3.8 KDM1B lysine demethylase 1B 0 6.1 MTF2 metal response element binding transcription factor 2 0 8.2 BAHD1 bromo adjacent homology domain containing 1 0 5.6 DHX30 DExH-box helicase 30 0 8.75 SIRT2 sirtuin 2 0 7.6 SCMH1 sex comb on midleg homolog 1 (Drosophila) 0 7.3 KDM2A lysine demethylase 2A 0 7.85 KDM1A lysine demethylase 1A 0 9.1 KDM4B lysine demethylase 4B 0 7.2 NCOA6 nuclear receptor coactivator 6 0 9.8 SETD1B SET domain containing 1B 0 9.1 KDM4C lysine demethylase 4C 0 5.8 POGZ pogo transposable element derived with ZNF domain 0 9.1 KDM6B lysine demethylase 6B 0 5.7 RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component 0 7.2 JMJD6 arginine demethylase and lysine hydroxylase 0 6.3 JADE2 jade family PHD finger 2 0 7.15 SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0 8.6 PHF24 PHD finger protein 24 0 3.8 ADNP activity dependent neuroprotector homeobox 0 10.4 SIRT5 sirtuin 5 0 6.3 SIRT4 sirtuin 4 0 4.2 SIRT3 sirtuin 3 0 6.6 TDRD7 tudor domain containing 7 0 8.4 CBX6 chromobox 6 0 9.1 CBX5 chromobox 5 0 9 CBX7 chromobox 7 0 6.2 ZMYND8 zinc finger MYND-type containing 8 0 9.35 BRD1 bromodomain containing 1 0 7.6 ZBTB38 zinc finger and BTB domain containing 38 0 8.2 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 0 3.6 SHPRH SNF2 histone linker PHD RING helicase 0 8.2 SETBP1 SET binding protein 1 0 5.5 EPC2 enhancer of polycomb homolog 2 0 8 PHF19 PHD finger protein 19 0 9.3 KAT2A lysine acetyltransferase 2A 0 8.3 SND1 staphylococcal nuclease and tudor domain containing 1 0 9.8 BRPF3 bromodomain and PHD finger containing 3 0 6.35 CECR2 CECR2, histone acetyl-lysine reader 0 4.15 ATAD2 ATPase family, AAA domain containing 2 0 10 SETD2 SET domain containing 2 0 7.3 BRD7 bromodomain containing 7 0 9.3 GTF3C1 general transcription factor IIIC subunit 1 0 8.4 HCFC2 host cell factor C2 0 6.4 DNMT3L DNA methyltransferase 3 like 0 4.4 BAZ2B bromodomain adjacent to zinc finger domain 2B 0 8.3 HDAC1 histone deacetylase 1 0 10.2 HDGF heparin binding growth factor 0 11.2 HELLS helicase, lymphoid-specific 0 9 CXXC1 CXXC finger protein 1 0 8.2 AIRE autoimmune regulator 0 4.6 PRMT2 protein arginine methyltransferase 2 0 7.4 PRMT1 protein arginine methyltransferase 1 0 12.3 APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 0 3.9 IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic 0 12.2 ING2 inhibitor of growth family member 2 0 9.3 KMT5A lysine methyltransferase 5A 0 7.8 LBR lamin B receptor 0 10.95 MBD1 methyl-CpG binding domain protein 1 0 6.9 MGMT O-6-methylguanine-DNA methyltransferase 0 7.9 RERE arginine-glutamic acid dipeptide repeats 0 5.2 PHF20L1 PHD finger protein 20-like 1 0 7.5 KMT5B lysine methyltransferase 5B 0 9.1 PCNA proliferating cell nuclear antigen 0 12.6 PHF11 PHD finger protein 11 0 8.5 ING4 inhibitor of growth family member 4 0 7.2 PHF20 PHD finger protein 20 0 8.6 PHF21A PHD finger protein 21A 0 6.6 ACTL6B actin like 6B 0 4.3 SFMBT1 Scm-like with four mbt domains 1 0 5.9 PHF7 PHD finger protein 7 0 4.7 SIRT7 sirtuin 7 0 8.6 SIRT6 sirtuin 6 0 6 HDAC7 histone deacetylase 7 0 6.1 ARID4B AT-rich interaction domain 4B 0 8.5 RSF1 remodeling and spacing factor 1 0 8.1 KDM3B lysine demethylase 3B 0 8.8 PHF1 PHD finger protein 1 0 8 PHF2 PHD finger protein 2 0 8.2 MBD3 methyl-CpG binding domain protein 3 0 8.35 BRWD1 bromodomain and WD repeat domain containing 1 0 6.3 SETD4 SET domain containing 4 0 7.1 POLE3 DNA polymerase epsilon 3, accessory subunit 0 10.4 CHRAC1 chromatin accessibility complex 1 0 7.7 ATAD2B ATPase family, AAA domain containing 2B 0 6.6 PRMT7 protein arginine methyltransferase 7 0 6.7 ING3 inhibitor of growth family member 3 0 7.55 INO80 INO80 complex subunit 0 7.8 MPHOSPH8 M-phase phosphoprotein 8 0 8.2 MBTD1 mbt domain containing 1 0 7.7 GATAD2A GATA zinc finger domain containing 2A 0 7.8 ZCWPW1 zinc finger CW-type and PWWP domain containing 1 0 5.5 ELP3 elongator acetyltransferase complex subunit 3 0 8.5 UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0 9.6 PRMT6 protein arginine methyltransferase 6 0 7.9 PBRM1 polybromo 1 0 7.35 SETD5 SET domain containing 5 0 7.4 ASXL2 additional sex combs like 2, transcriptional regulator 0 6.4 MRGBP MRG domain binding protein 0 9.15 PHF10 PHD finger protein 10 0 9.5 CHD7 chromodomain helicase DNA binding protein 7 0 8 PPP4R3A protein phosphatase 4 regulatory subunit 3A 0 8.45 KDM4D lysine demethylase 4D 0 4.55 ATF7IP activating transcription factor 7 interacting protein 0 9.1 MBD5 methyl-CpG binding domain protein 5 0 5.1 KDM3A lysine demethylase 3A 0 9.5 ASH1L ASH1 like histone lysine methyltransferase 0 9.5 KMT2E lysine methyltransferase 2E 0 9.4 DMAP1 DNA methyltransferase 1 associated protein 1 0 8 RNF17 ring finger protein 17 0 3.9 TDRD1 tudor domain containing 1 0 3.7 PRMT8 protein arginine methyltransferase 8 0 4.35 SMYD2 SET and MYND domain containing 2 0 10.5 PRDM8 PR/SET domain 8 0 3.8 PRDM9 PR/SET domain 9 0 3.6 PRDM10 PR/SET domain 10 0 6.5 PRDM11 PR/SET domain 11 0 4.2 INTS12 integrator complex subunit 12 0 9.2 PPP4R3B protein phosphatase 4 regulatory subunit 3B 0 8.8 CBX8 chromobox 8 0 5.9 AICDA activation induced cytidine deaminase 0 3.7 GATAD2B GATA zinc finger domain containing 2B 0 7.1 ARID1B AT-rich interaction domain 1B 0 6.8 MTA3 metastasis associated 1 family member 3 0 8.4 BAHCC1 BAH domain and coiled-coil containing 1 0 4.9 PHF12 PHD finger protein 12 0 5.9 ZBTB4 zinc finger and BTB domain containing 4 0 8.3 PHRF1 PHD and ring finger domains 1 0 6.6 SFMBT2 Scm-like with four mbt domains 2 0 4.3 NCOA5 nuclear receptor coactivator 5 0 6.7 RAG2 recombination activating 2 0 3.5 ACTA1 actin, alpha 1, skeletal muscle 0 4 ARID4A AT-rich interaction domain 4A 0 6.7 RBBP4 RB binding protein 4, chromatin remodeling factor 0 7.7 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 0 7.3 PRDM12 PR/SET domain 12 0 4 PRDM13 PR/SET domain 13 0 5 DPF2 double PHD fingers 2 0 9 RING1 ring finger protein 1 0 9.2 RNF2 ring finger protein 2 0 7.15 ACTB actin beta 0 13 ATXN7 ataxin 7 0 6.2 PRDM15 PR/SET domain 15 0 4.8 PRDM14 PR/SET domain 14 0 4.9 PRDM1 PR/SET domain 1 0 5.2 SETMAR SET domain and mariner transposase fusion gene 0 7.9 ACTR6 ARP6 actin related protein 6 homolog 0 10.1 SMYD3 SET and MYND domain containing 3 0 9.1 MEAF6 MYST/Esa1 associated factor 6 0 7 BRD9 bromodomain containing 9 0 8 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 0 8.6 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 0 8.1 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0 6.4 SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0 7.6 SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0 6 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0 10.9 SP100 SP100 nuclear antigen 0 6.8 TCF19 transcription factor 19 0 7.7 TCF20 transcription factor 20 0 8.3 VPS72 vacuolar protein sorting 72 homolog 0 10.2 YY1 YY1 transcription factor 0 11.8 PCGF2 polycomb group ring finger 2 0 6.75 PRDM2 PR/SET domain 2 0 6.2 BRPF1 bromodomain and PHD finger containing 1 0 7.7 FTO FTO, alpha-ketoglutarate dependent dioxygenase 0 9.2 PHF23 PHD finger protein 23 0 8.5 RIOX1 ribosomal oxygenase 1 0 8.5 TBL1XR1 transducin beta like 1 X-linked receptor 1 0 9.5 SUV39H2 suppressor of variegation 3-9 homolog 2 0 7.3 EHMT1 euchromatic histone lysine methyltransferase 1 0 7 ZMYM1 zinc finger MYM-type containing 1 0 7.8 KDM8 lysine demethylase 8 0 4.4 HDAC11 histone deacetylase 11 0 5.9 ACTR5 ARP5 actin related protein 5 homolog 0 7 SETD6 SET domain containing 6 0 8.3 JADE1 jade family PHD finger 1 0 8.1 PHC3 polyhomeotic homolog 3 0 7.4 EPC1 enhancer of polycomb homolog 1 0 4.7 ASXL3 additional sex combs like 3, transcriptional regulator 0 4.1 KDM7A lysine demethylase 7A 0 5.55 SETD7 SET domain containing lysine methyltransferase 7 0 10 FXR1 FMR1 autosomal homolog 1 0 7.2 YEATS4 YEATS domain containing 4 0 8.1 TDRD3 tudor domain containing 3 0 7.1 AKAP1 A-kinase anchoring protein 1 0 9.25 DPF1 double PHD fingers 1 0 5.9 L3MBTL2 L3MBTL2 polycomb repressive complex 1 subunit 0 7.3 SETDB2 SET domain bifurcated 2 0 5.1 TAF3 TATA-box binding protein associated factor 3 0 6.7 HDAC10 histone deacetylase 10 0 4.7 CHD6 chromodomain helicase DNA binding protein 6 0 4.8 SETD3 SET domain containing 3 0 7.7 ING5 inhibitor of growth family member 5 0 6.6 RAD54L RAD54 like (S. cerevisiae) 0 8.05 DOT1L DOT1 like histone lysine methyltransferase 0 6.3 L3MBTL3 l(3)mbt-like 3 (Drosophila) 0 5.9 TTF2 transcription termination factor 2 0 8.7 ZGPAT zinc finger CCCH-type and G-patch domain containing 0 7.6 GLYR1 glyoxylate reductase 1 homolog 0 6.5 KDM2B lysine demethylase 2B 0 8.65 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0 9.7 CBX2 chromobox 2 0 5.5 PCGF1 polycomb group ring finger 1 0 8.8 KMT5C lysine methyltransferase 5C 0 5.5 RIOX2 ribosomal oxygenase 2 0 8.65 MUM1 melanoma associated antigen (mutated) 1 0 6.8 HAT1 histone acetyltransferase 1 0 11.3 CBX4 chromobox 4 0 8.3 RUVBL1 RuvB like AAA ATPase 1 0 10.4 ACTL6A actin like 6A 0 10.6 EED embryonic ectoderm development 0 6.1 ALKBH1 alkB homolog 1, histone H2A dioxygenase 0 7.4 KAT2B lysine acetyltransferase 2B 0 7.2 MBD4 methyl-CpG binding domain 4, DNA glycosylase 0 9.9 MBD2 methyl-CpG binding domain protein 2 0 4.3 BAZ1B bromodomain adjacent to zinc finger domain 1B 0 8.1 BTAF1 B-TFIID TATA-box binding protein associated factor 1 0 9.2 PYGO2 pygopus family PHD finger 2 0 7.2 PRMT9 protein arginine methyltransferase 9 0 8.1 MTA1 metastasis associated 1 0 7.3 L3MBTL4 l(3)mbt-like 4 (Drosophila) 0 4.3 ZMYM4 zinc finger MYM-type containing 4 0 8.9 ZMYM6 zinc finger MYM-type containing 6 0 6.5 ZMYM5 zinc finger MYM-type containing 5 0 6.1 MTA2 metastasis associated 1 family member 2 0 5 GLYATL1 glycine-N-acyltransferase like 1 0 3.8 PRDM6 PR/SET domain 6 0 4.9 GTF3C4 general transcription factor IIIC subunit 4 0 8.8 ACTR8 ARP8 actin related protein 8 homolog 0 6.8 CDYL chromodomain Y like 0 8.65 FXR2 FMR1 autosomal homolog 2 0 7.5 CLOCK clock circadian regulator 0 8.8 NCOR1 nuclear receptor corepressor 1 0 7.8 PHF14 PHD finger protein 14 0 7.1 KDM4A lysine demethylase 4A 0 7.5 HDAC9 histone deacetylase 9 0 4.6 SETD1A SET domain containing 1A 0 5.5 KMT2B lysine methyltransferase 2B 0 5.2 TRIM66 tripartite motif containing 66 0 5.4