Symbol	Name	mut_rate	expr_median
TAF1L	TATA-box binding protein associated factor 1 like	24	4.3
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	20	9
NCOA3	nuclear receptor coactivator 3	20	8.7
CREBBP	CREB binding protein	16	6.8
EP300	E1A binding protein p300	16	8.1
MGA	MGA, MAX dimerization protein	16	8.2
TRRAP	transformation/transcription domain associated protein	16	8.2
TRIM28	tripartite motif containing 28	12	10.4
NCOA2	nuclear receptor coactivator 2	12	5
CHD8	chromodomain helicase DNA binding protein 8	12	8.5
KMT2C	lysine methyltransferase 2C	12	7.7
NSD2	nuclear receptor binding SET domain protein 2	12	7.6
NCOA1	nuclear receptor coactivator 1	12	7.9
KAT6A	lysine acetyltransferase 6A	12	NA
ERCC6	ERCC excision repair 6, chromatin remodeling factor	8	5.4
NIPBL	NIPBL, cohesin loading factor	8	8.9
KMT2A	lysine methyltransferase 2A	8	7.5
TET2	tet methylcytosine dioxygenase 2	8	6.2
KDM5A	lysine demethylase 5A	8	7.1
PRDM16	PR/SET domain 16	8	3.7
BRD3	bromodomain containing 3	8	9.4
MLLT10	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10	8	7.3
HDAC6	histone deacetylase 6	8	NA
ATRX	ATRX, chromatin remodeler	8	NA
KAT6B	lysine acetyltransferase 6B	8	NA
CHD1	chromodomain helicase DNA binding protein 1	4	9.3
PSIP1	PC4 and SFRS1 interacting protein 1	4	9.6
DNMT1	DNA methyltransferase 1	4	11.3
DNMT3B	DNA methyltransferase 3 beta	4	8
SUZ12	SUZ12 polycomb repressive complex 2 subunit	4	10.5
CHD5	chromodomain helicase DNA binding protein 5	4	4.1
MSH6	mutS homolog 6	4	9.9
TFPT	TCF3 fusion partner	4	7.2
HDAC2	histone deacetylase 2	4	7
LMNA	lamin A/C	4	9.6
MLLT6	MLLT6, PHD finger domain containing	4	7.7
PCNA	proliferating cell nuclear antigen	4	12.5
NSD3	nuclear receptor binding SET domain protein 3	4	7.1
PHIP	pleckstrin homology domain interacting protein	4	9.4
STK31	serine/threonine kinase 31	4	5
EP400	E1A binding protein p400	4	7.5
BRD2	bromodomain containing 2	4	9.9
NSD1	nuclear receptor binding SET domain protein 1	4	6
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	4	6.9
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	4	9.4
BRDT	bromodomain testis associated	4	3.8
HNF1A	HNF1 homeobox A	4	4.2
TP53BP1	tumor protein p53 binding protein 1	4	6.9
CHD9	chromodomain helicase DNA binding protein 9	4	9
ARID1A	AT-rich interaction domain 1A	4	8.6
LMNB2	lamin B2	4	7.8
HDAC3	histone deacetylase 3	4	8.9
SETDB1	SET domain bifurcated 1	4	6.6
TAF1	TATA-box binding protein associated factor 1	4	NA
KDM6A	lysine demethylase 6A	4	NA
HDAC5	histone deacetylase 5	0	5.6
PRMT3	protein arginine methyltransferase 3	0	9.8
SMNDC1	survival motor neuron domain containing 1	0	10.4
IKZF1	IKAROS family zinc finger 1	0	3.9
SMYD5	SMYD family member 5	0	7
PRMT5	protein arginine methyltransferase 5	0	10.4
CARM1	coactivator associated arginine methyltransferase 1	0	8.9
KAT5	lysine acetyltransferase 5	0	8.1
CTCF	CCCTC-binding factor	0	9.9
RAI1	retinoic acid induced 1	0	7.6
KDM5B	lysine demethylase 5B	0	9.3
ZMYND11	zinc finger MYND-type containing 11	0	7.7
SRCAP	Snf2 related CREBBP activator protein	0	5.3
RUVBL2	RuvB like AAA ATPase 2	0	11.3
BRD8	bromodomain containing 8	0	7.7
EHMT2	euchromatic histone lysine methyltransferase 2	0	7
MORF4L1	mortality factor 4 like 1	0	12.9
TDRKH	tudor and KH domain containing	0	4.9
CHD2	chromodomain helicase DNA binding protein 2	0	8.3
CHD3	chromodomain helicase DNA binding protein 3	0	7.4
DIDO1	death inducer-obliterator 1	0	7.1
CHD4	chromodomain helicase DNA binding protein 4	0	9.7
WDR5	WD repeat domain 5	0	8.4
PRDM7	PR/SET domain 7	0	4
PRDM5	PR/SET domain 5	0	4.2
PRDM4	PR/SET domain 4	0	7.8
BAZ2A	bromodomain adjacent to zinc finger domain 2A	0	6.6
BAZ1A	bromodomain adjacent to zinc finger domain 1A	0	10.1
SP140	SP140 nuclear body protein	0	4
SGF29	SAGA complex associated factor 29	0	8
PHF21B	PHD finger protein 21B	0	3.9
CBX3	chromobox 3	0	12.2
MBD6	methyl-CpG binding domain protein 6	0	7.9
SMYD4	SET and MYND domain containing 4	0	7.8
UHRF2	ubiquitin like with PHD and ring finger domains 2	0	9.8
AEBP2	AE binding protein 2	0	7
TDRD9	tudor domain containing 9	0	3.7
CDYL2	chromodomain Y like 2	0	5.2
INO80C	INO80 complex subunit C	0	9.5
TDRD10	tudor domain containing 10	0	4.5
SETD9	SET domain containing 9	0	7.3
NCOA7	nuclear receptor coactivator 7	0	10.4
ATF2	activating transcription factor 2	0	5.8
PHF13	PHD finger protein 13	0	9.1
SMYD1	SET and MYND domain containing 1	0	3.9
ZCWPW2	zinc finger CW-type and PWWP domain containing 2	0	3.5
KIAA2026	KIAA2026	0	7.4
DAXX	death domain associated protein	0	8.1
TDRD5	tudor domain containing 5	0	4.3
PWWP2B	PWWP domain containing 2B	0	5.6
ASXL1	additional sex combs like 1, transcriptional regulator	0	8.3
TRDMT1	tRNA aspartic acid methyltransferase 1	0	6
DNMT3A	DNA methyltransferase 3 alpha	0	5.5
DUSP1	dual specificity phosphatase 1	0	7.9
PHC2	polyhomeotic homolog 2	0	9.2
ARID2	AT-rich interaction domain 2	0	8.6
TET3	tet methylcytosine dioxygenase 3	0	6.9
EYA4	EYA transcriptional coactivator and phosphatase 4	0	4.3
MECOM	MDS1 and EVI1 complex locus	0	7.8
EYA1	EYA transcriptional coactivator and phosphatase 1	0	4.4
EYA2	EYA transcriptional coactivator and phosphatase 2	0	6.3
EYA3	EYA transcriptional coactivator and phosphatase 3	0	6.9
EZH1	enhancer of zeste 1 polycomb repressive complex 2 subunit	0	6.9
EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	0	9
BPTF	bromodomain PHD finger transcription factor	0	8.3
JMJD1C	jumonji domain containing 1C	0	7.9
ALKBH3	alkB homolog 3, alpha-ketoglutaratedependent dioxygenase	0	8.7
TDRD6	tudor domain containing 6	0	3.8
KDM1B	lysine demethylase 1B	0	5.9
MTF2	metal response element binding transcription factor 2	0	8.3
BAHD1	bromo adjacent homology domain containing 1	0	5.6
DHX30	DExH-box helicase 30	0	8.7
SIRT2	sirtuin 2	0	7.5
SCMH1	sex comb on midleg homolog 1 (Drosophila)	0	6.8
KDM2A	lysine demethylase 2A	0	8.4
KDM1A	lysine demethylase 1A	0	9.2
KDM4B	lysine demethylase 4B	0	7.2
NCOA6	nuclear receptor coactivator 6	0	9.7
SETD1B	SET domain containing 1B	0	9
KDM4C	lysine demethylase 4C	0	5.8
POGZ	pogo transposable element derived with ZNF domain	0	8.8
KDM6B	lysine demethylase 6B	0	5.9
RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component	0	7.2
JMJD6	arginine demethylase and lysine hydroxylase	0	6.1
JADE2	jade family PHD finger 2	0	7.8
SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	0	8.7
PHF24	PHD finger protein 24	0	3.9
ADNP	activity dependent neuroprotector homeobox	0	10.4
SIRT5	sirtuin 5	0	6.6
SIRT4	sirtuin 4	0	4.1
SIRT3	sirtuin 3	0	6.8
SIRT1	sirtuin 1	0	8.5
TDRD7	tudor domain containing 7	0	8.3
CBX6	chromobox 6	0	9.4
CBX5	chromobox 5	0	8.4
PHF3	PHD finger protein 3	0	8.5
BRD4	bromodomain containing 4	0	8.2
CBX7	chromobox 7	0	6.5
ZMYND8	zinc finger MYND-type containing 8	0	9.2
BRD1	bromodomain containing 1	0	7.7
ZBTB38	zinc finger and BTB domain containing 38	0	7.9
GABRG1	gamma-aminobutyric acid type A receptor gamma1 subunit	0	3.6
SHPRH	SNF2 histone linker PHD RING helicase	0	8.1
SETBP1	SET binding protein 1	0	6.4
EPC2	enhancer of polycomb homolog 2	0	7.6
PHF19	PHD finger protein 19	0	9.1
KAT2A	lysine acetyltransferase 2A	0	8.3
SND1	staphylococcal nuclease and tudor domain containing 1	0	9.6
BRPF3	bromodomain and PHD finger containing 3	0	6.2
CECR2	CECR2, histone acetyl-lysine reader	0	4.2
ATAD2	ATPase family, AAA domain containing 2	0	9.8
SETD2	SET domain containing 2	0	7.4
BRD7	bromodomain containing 7	0	9.5
GTF3C1	general transcription factor IIIC subunit 1	0	8.2
HCFC2	host cell factor C2	0	6
DNMT3L	DNA methyltransferase 3 like	0	4.2
BAZ2B	bromodomain adjacent to zinc finger domain 2B	0	8.5
HDAC1	histone deacetylase 1	0	10.6
HDGF	heparin binding growth factor	0	11.3
HELLS	helicase, lymphoid-specific	0	9.1
CXXC1	CXXC finger protein 1	0	7.9
AIRE	autoimmune regulator	0	4.6
PRMT2	protein arginine methyltransferase 2	0	7.2
PRMT1	protein arginine methyltransferase 1	0	12.2
APOBEC1	apolipoprotein B mRNA editing enzyme catalytic subunit 1	0	3.9
IDH1	isocitrate dehydrogenase (NADP(+)) 1, cytosolic	0	12.4
IDH2	isocitrate dehydrogenase (NADP(+)) 2, mitochondrial	0	9.2
SP110	SP110 nuclear body protein	0	7
ING1	inhibitor of growth family member 1	0	7.5
ING2	inhibitor of growth family member 2	0	9.1
JARID2	jumonji and AT-rich interaction domain containing 2	0	7.9
KMT5A	lysine methyltransferase 5A	0	7.5
LBR	lamin B receptor	0	10.8
LMNB1	lamin B1	0	9.7
MBD1	methyl-CpG binding domain protein 1	0	6.4
MEN1	menin 1	0	8.9
MGMT	O-6-methylguanine-DNA methyltransferase	0	7.8
RERE	arginine-glutamic acid dipeptide repeats	0	5
PHF20L1	PHD finger protein 20-like 1	0	7.6
KMT5B	lysine methyltransferase 5B	0	9.3
PHF11	PHD finger protein 11	0	8.6
ING4	inhibitor of growth family member 4	0	7.2
PHF20	PHD finger protein 20	0	8.3
PHF21A	PHD finger protein 21A	0	6.4
ACTL6B	actin like 6B	0	4.2
SFMBT1	Scm-like with four mbt domains 1	0	5.9
PHF7	PHD finger protein 7	0	4.7
SIRT7	sirtuin 7	0	8.9
SIRT6	sirtuin 6	0	6
HDAC7	histone deacetylase 7	0	6.4
TRIM33	tripartite motif containing 33	0	8.8
ARID4B	AT-rich interaction domain 4B	0	8.6
RSF1	remodeling and spacing factor 1	0	8.1
KDM3B	lysine demethylase 3B	0	8.8
PHF1	PHD finger protein 1	0	7.8
PHF2	PHD finger protein 2	0	8.4
MBD3	methyl-CpG binding domain protein 3	0	8.3
BRWD1	bromodomain and WD repeat domain containing 1	0	6.1
SETD4	SET domain containing 4	0	6.9
POLE3	DNA polymerase epsilon 3, accessory subunit	0	10.6
CHRAC1	chromatin accessibility complex 1	0	7.6
ATAD2B	ATPase family, AAA domain containing 2B	0	6.5
PRMT7	protein arginine methyltransferase 7	0	6.6
ING3	inhibitor of growth family member 3	0	7
INO80	INO80 complex subunit	0	8
MPHOSPH8	M-phase phosphoprotein 8	0	8.4
MBTD1	mbt domain containing 1	0	7.7
GATAD2A	GATA zinc finger domain containing 2A	0	7.8
ZCWPW1	zinc finger CW-type and PWWP domain containing 1	0	5.5
ELP3	elongator acetyltransferase complex subunit 3	0	8.6
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	0	9.4
PRMT6	protein arginine methyltransferase 6	0	7.6
PBRM1	polybromo 1	0	7.1
SETD5	SET domain containing 5	0	7.6
ASXL2	additional sex combs like 2, transcriptional regulator	0	6.4
MRGBP	MRG domain binding protein	0	9.6
PHF10	PHD finger protein 10	0	9.3
CHD7	chromodomain helicase DNA binding protein 7	0	7.6
PPP4R3A	protein phosphatase 4 regulatory subunit 3A	0	8.4
KDM4D	lysine demethylase 4D	0	4.4
ATF7IP	activating transcription factor 7 interacting protein	0	9.4
MBD5	methyl-CpG binding domain protein 5	0	4.5
KDM3A	lysine demethylase 3A	0	9.5
ASH1L	ASH1 like histone lysine methyltransferase	0	9.5
KMT2E	lysine methyltransferase 2E	0	9.1
DMAP1	DNA methyltransferase 1 associated protein 1	0	7.8
RNF17	ring finger protein 17	0	4
TDRD1	tudor domain containing 1	0	3.7
PRMT8	protein arginine methyltransferase 8	0	4.3
SMYD2	SET and MYND domain containing 2	0	10.4
PRDM8	PR/SET domain 8	0	3.9
PRDM9	PR/SET domain 9	0	3.6
PRDM10	PR/SET domain 10	0	6.4
PRDM11	PR/SET domain 11	0	4.2
INTS12	integrator complex subunit 12	0	9.1
PPP4R3B	protein phosphatase 4 regulatory subunit 3B	0	9
CBX8	chromobox 8	0	5.7
AICDA	activation induced cytidine deaminase	0	3.7
GATAD2B	GATA zinc finger domain containing 2B	0	7.1
ARID1B	AT-rich interaction domain 1B	0	6.6
MTA3	metastasis associated 1 family member 3	0	8.4
BAHCC1	BAH domain and coiled-coil containing 1	0	4.9
PHF12	PHD finger protein 12	0	5.9
ZBTB4	zinc finger and BTB domain containing 4	0	8.8
PHRF1	PHD and ring finger domains 1	0	6.6
SFMBT2	Scm-like with four mbt domains 2	0	4.6
NCOA5	nuclear receptor coactivator 5	0	6.7
RAG2	recombination activating 2	0	3.5
ACTA1	actin, alpha 1, skeletal muscle	0	4
ARID4A	AT-rich interaction domain 4A	0	6.7
RBBP4	RB binding protein 4, chromatin remodeling factor	0	7.3
RBBP5	RB binding protein 5, histone lysine methyltransferase complex subunit	0	7.2
PRDM12	PR/SET domain 12	0	3.9
PRDM13	PR/SET domain 13	0	4.8
DPF2	double PHD fingers 2	0	9.2
RING1	ring finger protein 1	0	9.3
RNF2	ring finger protein 2	0	7
ACTB	actin beta	0	12.9
ATXN7	ataxin 7	0	6.5
PRDM15	PR/SET domain 15	0	4.6
PRDM14	PR/SET domain 14	0	5
PRDM1	PR/SET domain 1	0	5.5
SET	SET nuclear proto-oncogene	0	12.4
SETMAR	SET domain and mariner transposase fusion gene	0	7.5
ACTR6	ARP6 actin related protein 6 homolog	0	10
SMYD3	SET and MYND domain containing 3	0	8.5
MEAF6	MYST/Esa1 associated factor 6	0	6.5
BRD9	bromodomain containing 9	0	7.7
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	0	8.6
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	0	8.1
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0	6.5
SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	0	8
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0	6.3
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0	10.5
SP100	SP100 nuclear antigen	0	6.7
TCF19	transcription factor 19	0	7.1
TCF20	transcription factor 20	0	8.4
VPS72	vacuolar protein sorting 72 homolog	0	10
YY1	YY1 transcription factor	0	12
PCGF2	polycomb group ring finger 2	0	6.6
ZMYM2	zinc finger MYM-type containing 2	0	5.6
PRDM2	PR/SET domain 2	0	6.3
BRPF1	bromodomain and PHD finger containing 1	0	7.4
FTO	FTO, alpha-ketoglutarate dependent dioxygenase	0	9.1
PHF23	PHD finger protein 23	0	8.7
RIOX1	ribosomal oxygenase 1	0	8.5
TBL1XR1	transducin beta like 1 X-linked receptor 1	0	10
SUV39H2	suppressor of variegation 3-9 homolog 2	0	7.2
EHMT1	euchromatic histone lysine methyltransferase 1	0	7.2
ZMYM1	zinc finger MYM-type containing 1	0	8
KDM8	lysine demethylase 8	0	4.3
HDAC11	histone deacetylase 11	0	6.1
ACTR5	ARP5 actin related protein 5 homolog	0	7
SETD6	SET domain containing 6	0	8.2
JADE1	jade family PHD finger 1	0	7.2
PHC3	polyhomeotic homolog 3	0	7.9
TET1	tet methylcytosine dioxygenase 1	0	6.2
EPC1	enhancer of polycomb homolog 1	0	4.8
NCOA4	nuclear receptor coactivator 4	0	12
ASXL3	additional sex combs like 3, transcriptional regulator	0	4
KDM7A	lysine demethylase 7A	0	5.1
SETD7	SET domain containing lysine methyltransferase 7	0	9.6
KMT2D	lysine methyltransferase 2D	0	6.9
FXR1	FMR1 autosomal homolog 1	0	7.5
YEATS4	YEATS domain containing 4	0	7.9
TDRD3	tudor domain containing 3	0	7.2
AKAP1	A-kinase anchoring protein 1	0	9.1
DPF1	double PHD fingers 1	0	5.7
BAP1	BRCA1 associated protein 1	0	7.2
L3MBTL2	L3MBTL2 polycomb repressive complex 1 subunit	0	7.2
SETDB2	SET domain bifurcated 2	0	5.1
TAF3	TATA-box binding protein associated factor 3	0	6.6
HDAC10	histone deacetylase 10	0	4.7
CHD6	chromodomain helicase DNA binding protein 6	0	4.8
SETD3	SET domain containing 3	0	7.7
ING5	inhibitor of growth family member 5	0	6.5
RAD54L	RAD54 like (S. cerevisiae)	0	7.5
DOT1L	DOT1 like histone lysine methyltransferase	0	6.1
L3MBTL3	l(3)mbt-like 3 (Drosophila)	0	6.2
TTF2	transcription termination factor 2	0	8.8
ZGPAT	zinc finger CCCH-type and G-patch domain containing	0	7.7
TNRC18	trinucleotide repeat containing 18	0	6.3
GLYR1	glyoxylate reductase 1 homolog	0	6.6
KDM2B	lysine demethylase 2B	0	8.6
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0	9.6
CBX2	chromobox 2	0	5.4
PCGF1	polycomb group ring finger 1	0	8.8
KMT5C	lysine methyltransferase 5C	0	5.5
RIOX2	ribosomal oxygenase 2	0	8.9
MUM1	melanoma associated antigen (mutated) 1	0	7
HAT1	histone acetyltransferase 1	0	11.2
CBX4	chromobox 4	0	8.8
RUVBL1	RuvB like AAA ATPase 1	0	10.5
ACTL6A	actin like 6A	0	11
EED	embryonic ectoderm development	0	6.1
TRIM24	tripartite motif containing 24	0	8.7
ALKBH1	alkB homolog 1, histone H2A dioxygenase	0	7.7
KAT2B	lysine acetyltransferase 2B	0	6.5
MBD4	methyl-CpG binding domain 4, DNA glycosylase	0	9.9
MBD2	methyl-CpG binding domain protein 2	0	4.2
BAZ1B	bromodomain adjacent to zinc finger domain 1B	0	7.8
BTAF1	B-TFIID TATA-box binding protein associated factor 1	0	9.4
ASH2L	ASH2 like histone lysine methyltransferase complex subunit	0	9.8
PYGO2	pygopus family PHD finger 2	0	7.1
PRMT9	protein arginine methyltransferase 9	0	8.1
MTA1	metastasis associated 1	0	7.6
L3MBTL4	l(3)mbt-like 4 (Drosophila)	0	4.2
ZMYM4	zinc finger MYM-type containing 4	0	8.7
ZMYM6	zinc finger MYM-type containing 6	0	6.3
ZMYM5	zinc finger MYM-type containing 5	0	6.3
MTA2	metastasis associated 1 family member 2	0	5.1
GLYATL1	glycine-N-acyltransferase like 1	0	3.8
PRDM6	PR/SET domain 6	0	5
GTF3C4	general transcription factor IIIC subunit 4	0	9
SP140L	SP140 nuclear body protein like	0	8.5
ACTR8	ARP8 actin related protein 8 homolog	0	6.6
CDYL	chromodomain Y like	0	8.8
FXR2	FMR1 autosomal homolog 2	0	7.6
CLOCK	clock circadian regulator	0	8.7
NCOR1	nuclear receptor corepressor 1	0	7.9
PHF14	PHD finger protein 14	0	6.9
KDM4A	lysine demethylase 4A	0	7.4
HDAC9	histone deacetylase 9	0	4.6
SETD1A	SET domain containing 1A	0	5.6
KMT2B	lysine methyltransferase 2B	0	5.1
HDAC4	histone deacetylase 4	0	5.7
TRIM66	tripartite motif containing 66	0	5.5