*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).
| Node 1 | % Mutation Rate (Node 1) |
Node 2 | % Mutation Rate (Node 2) |
P Value (co-occurrence) |
P Value (mutual exclusive) |
|---|---|---|---|---|---|
| ACTB | 4.3 | ACTL6A | 1.5 | 0.234 | 0.976 |
| ACTB | 4.3 | ACTL6B | 1.8 | 1 | 0.733 |
| ACTB | 4.3 | BRD8 | 2.5 | 0.0644 | 0.993 |
| ACTB | 4.3 | CTNNB1 | 3.6 | 1 | 0.534 |
| ACTB | 4.3 | DMAP1 | 0.3 | 1 | 0.957 |
| ACTB | 4.3 | EP400 | 5.6 | 0.244 | 0.938 |
| ACTB | 4.3 | EPC1 | 2.8 | 0.0767 | 0.991 |
| ACTB | 4.3 | ING3 | 1.5 | 1 | 0.766 |
| ACTB | 4.3 | KAT5 | 1 | 1 | 0.838 |
| ACTB | 4.3 | MEAF6 | 0 | 1 | 1 |
| ACTB | 4.3 | MORF4L1 | 1.3 | 1 | 0.801 |
| ACTB | 4.3 | MORF4L2 | 0 | 1 | 1 |
| ACTB | 4.3 | MRGBP | 0.8 | 1 | 0.876 |
| ACTB | 4.3 | RUVBL1 | 1.5 | 1 | 0.766 |
| ACTB | 4.3 | RUVBL2 | 0.5 | 1 | 0.915 |
| ACTB | 4.3 | TRRAP | 8.6 | 0.173 | 0.951 |
| ACTB | 4.3 | VPS72 | 1.3 | 1 | 0.801 |
| ACTB | 4.3 | YEATS4 | 0.3 | 1 | 0.957 |
| ACTL6A | 1.5 | ACTL6B | 1.8 | 1 | 0.897 |
| ACTL6A | 1.5 | BRD8 | 2.5 | 1 | 0.856 |
| ACTL6A | 1.5 | DMAP1 | 0.3 | 1 | 0.985 |
| ACTL6A | 1.5 | EP400 | 5.6 | 0.039 | 0.997 |
| ACTL6A | 1.5 | EPC1 | 2.8 | 0.157 | 0.99 |
| ACTL6A | 1.5 | EPC2 | 1.8 | 1 | 0.897 |
| ACTL6A | 1.5 | ING3 | 1.5 | 0.0885 | 0.997 |
| ACTL6A | 1.5 | KAT5 | 1 | 1 | 0.94 |
| ACTL6A | 1.5 | MEAF6 | 0 | 1 | 1 |
| ACTL6A | 1.5 | MORF4L1 | 1.3 | 0.0742 | 0.998 |
| ACTL6A | 1.5 | MORF4L2 | 0 | 1 | 1 |
| ACTL6A | 1.5 | MRGBP | 0.8 | 1 | 0.955 |
| ACTL6A | 1.5 | RUVBL1 | 1.5 | 0.0885 | 0.997 |
| ACTL6A | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| ACTL6A | 1.5 | SRCAP | 8.6 | 0.42 | 0.913 |
| ACTL6A | 1.5 | TRRAP | 8.6 | 0.0871 | 0.99 |
| ACTL6A | 1.5 | VPS72 | 1.3 | 1 | 0.926 |
| ACTL6A | 1.5 | YEATS4 | 0.3 | 1 | 0.985 |
| ACTL6B | 1.8 | EP400 | 5.6 | 0.333 | 0.947 |
| ACTL6B | 1.8 | RUVBL1 | 1.5 | 1 | 0.897 |
| ACTL6B | 1.8 | RUVBL2 | 0.5 | 1 | 0.965 |
| ACTL6B | 1.8 | TRRAP | 8.6 | 1 | 0.529 |
| BCL9 | 3.8 | CREBBP | 12.2 | 0.565 | 0.728 |
| BCL9 | 3.8 | CTNNB1 | 3.6 | 1 | 0.575 |
| BCL9 | 3.8 | EP300 | 15.5 | 0.189 | 0.935 |
| BCL9 | 3.8 | EP400 | 5.6 | 1 | 0.416 |
| BCL9 | 3.8 | LEF1 | 0.8 | 1 | 0.89 |
| BCL9 | 3.8 | PYGO1 | 1.8 | 1 | 0.76 |
| BCL9 | 3.8 | PYGO2 | 1.5 | 1 | 0.791 |
| BCL9 | 3.8 | SMAD1 | 1.3 | 0.177 | 0.987 |
| BCL9 | 3.8 | SMAD4 | 2 | 0.0332 | 0.998 |
| BCL9 | 3.8 | SMAD5 | 0 | 1 | 1 |
| BCL9 | 3.8 | SRCAP | 8.6 | 0.0057 | 0.999 |
| BCL9 | 3.8 | TCF7L1 | 0 | 1 | 1 |
| BCL9 | 3.8 | TCF7L2 | 0.3 | 1 | 0.962 |
| BRD8 | 2.5 | DMAP1 | 0.3 | 1 | 0.975 |
| BRD8 | 2.5 | EP400 | 5.6 | 0.102 | 0.986 |
| BRD8 | 2.5 | EPC1 | 2.8 | 0.249 | 0.972 |
| BRD8 | 2.5 | EPC2 | 1.8 | 1 | 0.834 |
| BRD8 | 2.5 | ING3 | 1.5 | 1 | 0.856 |
| BRD8 | 2.5 | KAT5 | 1 | 1 | 0.902 |
| BRD8 | 2.5 | MEAF6 | 0 | 1 | 1 |
| BRD8 | 2.5 | MORF4L1 | 1.3 | 1 | 0.879 |
| BRD8 | 2.5 | MORF4L2 | 0 | 1 | 1 |
| BRD8 | 2.5 | MRGBP | 0.8 | 1 | 0.926 |
| BRD8 | 2.5 | RUVBL1 | 1.5 | 1 | 0.856 |
| BRD8 | 2.5 | RUVBL2 | 0.5 | 1 | 0.95 |
| BRD8 | 2.5 | SRCAP | 8.6 | 0.599 | 0.79 |
| BRD8 | 2.5 | TRRAP | 8.6 | 0.599 | 0.79 |
| BRD8 | 2.5 | VPS72 | 1.3 | 0.121 | 0.994 |
| BRD8 | 2.5 | YEATS4 | 0.3 | 1 | 0.975 |
| CDKN1A | 8.9 | CREBBP | 12.2 | 0.642 | 0.573 |
| CDKN1A | 8.9 | EP400 | 5.6 | 0.12 | 0.964 |
| CDKN1A | 8.9 | TP53 | 49.7 | 0.993 | 0.0175 |
| CREBBP | 12.2 | CTNNB1 | 3.6 | 0.526 | 0.764 |
| CREBBP | 12.2 | EP300 | 15.5 | 0.642 | 0.527 |
| CREBBP | 12.2 | EP400 | 5.6 | 0.517 | 0.727 |
| CREBBP | 12.2 | LEF1 | 0.8 | 0.323 | 0.96 |
| CREBBP | 12.2 | PYGO1 | 1.8 | 1 | 0.4 |
| CREBBP | 12.2 | PYGO2 | 1.5 | 1 | 0.456 |
| CREBBP | 12.2 | SMAD1 | 1.3 | 0.48 | 0.886 |
| CREBBP | 12.2 | SMAD4 | 2 | 0.65 | 0.747 |
| CREBBP | 12.2 | SMAD5 | 0 | 1 | 1 |
| CREBBP | 12.2 | SRCAP | 8.6 | 0.99 | 0.0608 |
| CREBBP | 12.2 | TCF7L1 | 0 | 1 | 1 |
| CREBBP | 12.2 | TCF7L2 | 0.3 | 1 | 0.878 |
| CREBBP | 12.2 | TP53 | 49.7 | 0.132 | 0.923 |
| CTNNB1 | 3.6 | EP300 | 15.5 | 0.909 | 0.333 |
| CTNNB1 | 3.6 | EP400 | 5.6 | 1 | 0.441 |
| CTNNB1 | 3.6 | KAT5 | 1 | 1 | 0.865 |
| CTNNB1 | 3.6 | LEF1 | 0.8 | 1 | 0.897 |
| CTNNB1 | 3.6 | PYGO1 | 1.8 | 1 | 0.775 |
| CTNNB1 | 3.6 | PYGO2 | 1.5 | 1 | 0.804 |
| CTNNB1 | 3.6 | RUVBL1 | 1.5 | 0.196 | 0.984 |
| CTNNB1 | 3.6 | RUVBL2 | 0.5 | 1 | 0.93 |
| CTNNB1 | 3.6 | SMAD1 | 1.3 | 1 | 0.834 |
| CTNNB1 | 3.6 | SMAD4 | 2 | 1 | 0.747 |
| CTNNB1 | 3.6 | SMAD5 | 0 | 1 | 1 |
| CTNNB1 | 3.6 | SRCAP | 8.6 | 0.724 | 0.656 |
| CTNNB1 | 3.6 | TCF7L1 | 0 | 1 | 1 |
| CTNNB1 | 3.6 | TCF7L2 | 0.3 | 1 | 0.964 |
| CTNNB1 | 3.6 | TRRAP | 8.6 | 0.344 | 0.889 |
| DMAP1 | 0.3 | EP400 | 5.6 | 0.0558 | 1 |
| DMAP1 | 0.3 | EPC1 | 2.8 | 1 | 0.972 |
| DMAP1 | 0.3 | EPC2 | 1.8 | 1 | 0.982 |
| DMAP1 | 0.3 | ING3 | 1.5 | 1 | 0.985 |
| DMAP1 | 0.3 | KAT5 | 1 | 1 | 0.99 |
| DMAP1 | 0.3 | MEAF6 | 0 | 1 | 1 |
| DMAP1 | 0.3 | MORF4L1 | 1.3 | 1 | 0.987 |
| DMAP1 | 0.3 | MORF4L2 | 0 | 1 | 1 |
| DMAP1 | 0.3 | MRGBP | 0.8 | 1 | 0.992 |
| DMAP1 | 0.3 | RUVBL1 | 1.5 | 1 | 0.985 |
| DMAP1 | 0.3 | RUVBL2 | 0.5 | 1 | 0.995 |
| DMAP1 | 0.3 | SRCAP | 8.6 | 1 | 0.914 |
| DMAP1 | 0.3 | TRRAP | 8.6 | 1 | 0.914 |
| DMAP1 | 0.3 | VPS72 | 1.3 | 0.0127 | 1 |
| DMAP1 | 0.3 | YEATS4 | 0.3 | 1 | 0.997 |
| EP300 | 15.5 | EP400 | 5.6 | 0.106 | 0.962 |
| EP300 | 15.5 | LEF1 | 0.8 | 0.397 | 0.936 |
| EP300 | 15.5 | PYGO1 | 1.8 | 1 | 0.305 |
| EP300 | 15.5 | PYGO2 | 1.5 | 0.638 | 0.766 |
| EP300 | 15.5 | SMAD1 | 1.3 | 0.173 | 0.972 |
| EP300 | 15.5 | SMAD4 | 2 | 1 | 0.257 |
| EP300 | 15.5 | SMAD5 | 0 | 1 | 1 |
| EP300 | 15.5 | SRCAP | 8.6 | 0.806 | 0.369 |
| EP300 | 15.5 | TCF7L1 | 0 | 1 | 1 |
| EP300 | 15.5 | TCF7L2 | 0.3 | 1 | 0.845 |
| EP300 | 15.5 | TP53 | 49.7 | 0.124 | 0.925 |
| EP400 | 5.6 | EPC1 | 2.8 | 1 | 0.527 |
| EP400 | 5.6 | EPC2 | 1.8 | 1 | 0.667 |
| EP400 | 5.6 | ING3 | 1.5 | 0.293 | 0.961 |
| EP400 | 5.6 | KAT5 | 1 | 1 | 0.794 |
| EP400 | 5.6 | LEF1 | 0.8 | 0.159 | 0.991 |
| EP400 | 5.6 | MEAF6 | 0 | 1 | 1 |
| EP400 | 5.6 | MORF4L1 | 1.3 | 1 | 0.749 |
| EP400 | 5.6 | MORF4L2 | 0 | 1 | 1 |
| EP400 | 5.6 | MRGBP | 0.8 | 0.159 | 0.991 |
| EP400 | 5.6 | PYGO1 | 1.8 | 1 | 0.667 |
| EP400 | 5.6 | PYGO2 | 1.5 | 1 | 0.707 |
| EP400 | 5.6 | RUVBL1 | 1.5 | 0.293 | 0.961 |
| EP400 | 5.6 | RUVBL2 | 0.5 | 1 | 0.891 |
| EP400 | 5.6 | SMAD1 | 1.3 | 0.251 | 0.973 |
| EP400 | 5.6 | SMAD4 | 2 | 1 | 0.629 |
| EP400 | 5.6 | SMAD5 | 0 | 1 | 1 |
| EP400 | 5.6 | SRCAP | 8.6 | 0.584 | 0.707 |
| EP400 | 5.6 | TCF7L1 | 0 | 1 | 1 |
| EP400 | 5.6 | TCF7L2 | 0.3 | 1 | 0.944 |
| EP400 | 5.6 | TP53 | 49.7 | 0.0585 | 0.978 |
| EP400 | 5.6 | TRRAP | 8.6 | 0.11 | 0.968 |
| EP400 | 5.6 | VPS72 | 1.3 | 0.0269 | 0.999 |
| EP400 | 5.6 | YEATS4 | 0.3 | 1 | 0.944 |
| EPC1 | 2.8 | EPC2 | 1.8 | 1 | 0.819 |
| EPC1 | 2.8 | ING3 | 1.5 | 1 | 0.843 |
| EPC1 | 2.8 | KAT5 | 1 | 1 | 0.893 |
| EPC1 | 2.8 | MEAF6 | 0 | 1 | 1 |
| EPC1 | 2.8 | MORF4L1 | 1.3 | 1 | 0.867 |
| EPC1 | 2.8 | MORF4L2 | 0 | 1 | 1 |
| EPC1 | 2.8 | MRGBP | 0.8 | 1 | 0.918 |
| EPC1 | 2.8 | RUVBL1 | 1.5 | 1 | 0.843 |
| EPC1 | 2.8 | RUVBL2 | 0.5 | 1 | 0.945 |
| EPC1 | 2.8 | SRCAP | 8.6 | 0.634 | 0.756 |
| EPC1 | 2.8 | TRRAP | 8.6 | 0.06 | 0.99 |
| EPC1 | 2.8 | VPS72 | 1.3 | 0.133 | 0.993 |
| EPC1 | 2.8 | YEATS4 | 0.3 | 1 | 0.972 |
| EPC2 | 1.8 | ING3 | 1.5 | 0.103 | 0.996 |
| EPC2 | 1.8 | KAT5 | 1 | 1 | 0.931 |
| EPC2 | 1.8 | MEAF6 | 0 | 1 | 1 |
| EPC2 | 1.8 | MORF4L1 | 1.3 | 1 | 0.914 |
| EPC2 | 1.8 | MRGBP | 0.8 | 1 | 0.948 |
| EPC2 | 1.8 | RUVBL1 | 1.5 | 1 | 0.897 |
| EPC2 | 1.8 | RUVBL2 | 0.5 | 1 | 0.965 |
| EPC2 | 1.8 | TRRAP | 8.6 | 1 | 0.529 |
| EPC2 | 1.8 | YEATS4 | 0.3 | 1 | 0.982 |
| ING3 | 1.5 | KAT5 | 1 | 1 | 0.94 |
| ING3 | 1.5 | MEAF6 | 0 | 1 | 1 |
| ING3 | 1.5 | MORF4L1 | 1.3 | 1 | 0.926 |
| ING3 | 1.5 | MORF4L2 | 0 | 1 | 1 |
| ING3 | 1.5 | MRGBP | 0.8 | 1 | 0.955 |
| ING3 | 1.5 | RUVBL1 | 1.5 | 0.0885 | 0.997 |
| ING3 | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| ING3 | 1.5 | TRRAP | 8.6 | 1 | 0.58 |
| ING3 | 1.5 | VPS72 | 1.3 | 1 | 0.926 |
| ING3 | 1.5 | YEATS4 | 0.3 | 1 | 0.985 |
| KAT5 | 1 | LEF1 | 0.8 | 1 | 0.97 |
| KAT5 | 1 | MEAF6 | 0 | 1 | 1 |
| KAT5 | 1 | MORF4L1 | 1.3 | 1 | 0.95 |
| KAT5 | 1 | MORF4L2 | 0 | 1 | 1 |
| KAT5 | 1 | MRGBP | 0.8 | 1 | 0.97 |
| KAT5 | 1 | RUVBL1 | 1.5 | 1 | 0.94 |
| KAT5 | 1 | RUVBL2 | 0.5 | 1 | 0.98 |
| KAT5 | 1 | TCF7L1 | 0 | 1 | 1 |
| KAT5 | 1 | TCF7L2 | 0.3 | 1 | 0.99 |
| KAT5 | 1 | TRRAP | 8.6 | 1 | 0.696 |
| KAT5 | 1 | VPS72 | 1.3 | 1 | 0.95 |
| KAT5 | 1 | YEATS4 | 0.3 | 1 | 0.99 |
| LEF1 | 0.8 | PYGO1 | 1.8 | 1 | 0.948 |
| LEF1 | 0.8 | PYGO2 | 1.5 | 1 | 0.955 |
| LEF1 | 0.8 | RUVBL1 | 1.5 | 0.0451 | 0.999 |
| LEF1 | 0.8 | SMAD1 | 1.3 | 0.0377 | 1 |
| LEF1 | 0.8 | SMAD4 | 2 | 1 | 0.94 |
| LEF1 | 0.8 | SMAD5 | 0 | 1 | 1 |
| LEF1 | 0.8 | SRCAP | 8.6 | 1 | 0.762 |
| LEF1 | 0.8 | TRRAP | 8.6 | 1 | 0.762 |
| MEAF6 | 0 | MORF4L1 | 1.3 | 1 | 1 |
| MEAF6 | 0 | MORF4L2 | 0 | 1 | 1 |
| MEAF6 | 0 | MRGBP | 0.8 | 1 | 1 |
| MEAF6 | 0 | RUVBL1 | 1.5 | 1 | 1 |
| MEAF6 | 0 | RUVBL2 | 0.5 | 1 | 1 |
| MEAF6 | 0 | TP53 | 49.7 | 1 | 1 |
| MEAF6 | 0 | TRRAP | 8.6 | 1 | 1 |
| MEAF6 | 0 | VPS72 | 1.3 | 1 | 1 |
| MEAF6 | 0 | YEATS4 | 0.3 | 1 | 1 |
| MORF4L1 | 1.3 | MORF4L2 | 0 | 1 | 1 |
| MORF4L1 | 1.3 | MRGBP | 0.8 | 0.0377 | 1 |
| MORF4L1 | 1.3 | RUVBL1 | 1.5 | 0.0742 | 0.998 |
| MORF4L1 | 1.3 | RUVBL2 | 0.5 | 1 | 0.975 |
| MORF4L1 | 1.3 | TRRAP | 8.6 | 0.0613 | 0.995 |
| MORF4L1 | 1.3 | VPS72 | 1.3 | 1 | 0.938 |
| MORF4L1 | 1.3 | YEATS4 | 0.3 | 1 | 0.987 |
| MORF4L2 | 0 | MRGBP | 0.8 | 1 | 1 |
| MORF4L2 | 0 | RUVBL1 | 1.5 | 1 | 1 |
| MORF4L2 | 0 | RUVBL2 | 0.5 | 1 | 1 |
| MORF4L2 | 0 | TRRAP | 8.6 | 1 | 1 |
| MORF4L2 | 0 | VPS72 | 1.3 | 1 | 1 |
| MORF4L2 | 0 | YEATS4 | 0.3 | 1 | 1 |
| MRGBP | 0.8 | RUVBL1 | 1.5 | 1 | 0.955 |
| MRGBP | 0.8 | RUVBL2 | 0.5 | 1 | 0.985 |
| MRGBP | 0.8 | TRRAP | 8.6 | 0.238 | 0.979 |
| MRGBP | 0.8 | VPS72 | 1.3 | 1 | 0.962 |
| MRGBP | 0.8 | YEATS4 | 0.3 | 1 | 0.992 |
| PYGO1 | 1.8 | SMAD1 | 1.3 | 1 | 0.914 |
| PYGO1 | 1.8 | SMAD4 | 2 | 1 | 0.865 |
| PYGO1 | 1.8 | SMAD5 | 0 | 1 | 1 |
| PYGO1 | 1.8 | SRCAP | 8.6 | 1 | 0.529 |
| PYGO1 | 1.8 | TCF7L1 | 0 | 1 | 1 |
| PYGO1 | 1.8 | TCF7L2 | 0.3 | 1 | 0.982 |
| PYGO2 | 1.5 | SMAD1 | 1.3 | 1 | 0.926 |
| PYGO2 | 1.5 | SMAD4 | 2 | 1 | 0.883 |
| PYGO2 | 1.5 | SMAD5 | 0 | 1 | 1 |
| PYGO2 | 1.5 | SRCAP | 8.6 | 1 | 0.58 |
| PYGO2 | 1.5 | TCF7L1 | 0 | 1 | 1 |
| PYGO2 | 1.5 | TCF7L2 | 0.3 | 1 | 0.985 |
| RUVBL1 | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| RUVBL1 | 1.5 | SRCAP | 8.6 | 0.0871 | 0.99 |
| RUVBL1 | 1.5 | TCF7L1 | 0 | 1 | 1 |
| RUVBL1 | 1.5 | TCF7L2 | 0.3 | 1 | 0.985 |
| RUVBL1 | 1.5 | TRRAP | 8.6 | 1 | 0.58 |
| RUVBL1 | 1.5 | VPS72 | 1.3 | 1 | 0.926 |
| RUVBL1 | 1.5 | YEATS4 | 0.3 | 1 | 0.985 |
| RUVBL2 | 0.5 | SRCAP | 8.6 | 0.165 | 0.993 |
| RUVBL2 | 0.5 | TCF7L2 | 0.3 | 1 | 0.995 |
| RUVBL2 | 0.5 | TRRAP | 8.6 | 1 | 0.835 |
| RUVBL2 | 0.5 | VPS72 | 1.3 | 1 | 0.975 |
| RUVBL2 | 0.5 | YEATS4 | 0.3 | 1 | 0.995 |
| SMAD1 | 1.3 | SMAD4 | 2 | 1 | 0.902 |
| SMAD1 | 1.3 | SRCAP | 8.6 | 1 | 0.635 |
| SMAD1 | 1.3 | TCF7L1 | 0 | 1 | 1 |
| SMAD1 | 1.3 | TCF7L2 | 0.3 | 1 | 0.987 |
| SMAD4 | 2 | SMAD5 | 0 | 1 | 1 |
| SMAD4 | 2 | SRCAP | 8.6 | 0.146 | 0.976 |
| SMAD4 | 2 | TCF7L1 | 0 | 1 | 1 |
| SMAD4 | 2 | TCF7L2 | 0.3 | 1 | 0.98 |
| SMAD5 | 0 | SRCAP | 8.6 | 1 | 1 |
| SMAD5 | 0 | TCF7L1 | 0 | 1 | 1 |
| SMAD5 | 0 | TCF7L2 | 0.3 | 1 | 1 |
| SRCAP | 8.6 | TCF7L1 | 0 | 1 | 1 |
| SRCAP | 8.6 | TCF7L2 | 0.3 | 1 | 0.914 |
| SRCAP | 8.6 | TRRAP | 8.6 | 0.335 | 0.843 |
| SRCAP | 8.6 | VPS72 | 1.3 | 0.365 | 0.939 |
| SRCAP | 8.6 | YEATS4 | 0.3 | 1 | 0.914 |
| TCF7L1 | 0 | TRRAP | 8.6 | 1 | 1 |
| TCF7L2 | 0.3 | TRRAP | 8.6 | 0.0863 | 1 |
| TRRAP | 8.6 | VPS72 | 1.3 | 0.365 | 0.939 |
| TRRAP | 8.6 | YEATS4 | 0.3 | 0.0863 | 1 |
| VPS72 | 1.3 | YEATS4 | 0.3 | 1 | 0.987 |