*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).
| Node 1 | % Mutation Rate (Node 1) |
Node 2 | % Mutation Rate (Node 2) |
P Value (co-occurrence) |
P Value (mutual exclusive) |
|---|---|---|---|---|---|
| ARNT | 2.3 | CREBBP | 12.2 | 1 | 0.307 |
| ARNT | 2.3 | EP300 | 15.5 | 0.784 | 0.582 |
| ARNT | 2.3 | HDAC7 | 0.8 | 1 | 0.933 |
| ARNT | 2.3 | HIF1A | 1.5 | 1 | 0.87 |
| ARNT | 2.3 | SMAD3 | 1.3 | 1 | 0.89 |
| ARNT | 2.3 | SMAD4 | 2 | 1 | 0.83 |
| BCL6 | 0.3 | HDAC7 | 0.8 | 1 | 0.992 |
| CREBBP | 12.2 | EP300 | 15.5 | 0.642 | 0.527 |
| CREBBP | 12.2 | HDAC7 | 0.8 | 0.323 | 0.96 |
| CREBBP | 12.2 | HIF1A | 1.5 | 1 | 0.456 |
| CREBBP | 12.2 | RBPJ | 0.8 | 1 | 0.677 |
| CREBBP | 12.2 | SMAD1 | 1.3 | 0.48 | 0.886 |
| CREBBP | 12.2 | SMAD2 | 1 | 0.0743 | 0.994 |
| CREBBP | 12.2 | SMAD3 | 1.3 | 1 | 0.52 |
| CREBBP | 12.2 | SMAD4 | 2 | 0.65 | 0.747 |
| CREBBP | 12.2 | SMAD5 | 0 | 1 | 1 |
| CREBBP | 12.2 | SMAD9 | 0.8 | 1 | 0.677 |
| CREBBP | 12.2 | SNW1 | 1.8 | 0.205 | 0.958 |
| CREBBP | 12.2 | TBL1XR1 | 2 | 1 | 0.35 |
| CREBBP | 12.2 | TBL1X | 1.3 | 1 | 0.52 |
| CREBBP | 12.2 | TLE1 | 1.5 | 0.544 | 0.842 |
| EP300 | 15.5 | HDAC7 | 0.8 | 0.397 | 0.936 |
| EP300 | 15.5 | HIF1A | 1.5 | 0.638 | 0.766 |
| EP300 | 15.5 | RBPJ | 0.8 | 0.0638 | 0.996 |
| EP300 | 15.5 | SMAD1 | 1.3 | 0.173 | 0.972 |
| EP300 | 15.5 | SMAD2 | 1 | 0.491 | 0.885 |
| EP300 | 15.5 | SMAD3 | 1.3 | 1 | 0.429 |
| EP300 | 15.5 | SMAD4 | 2 | 1 | 0.257 |
| EP300 | 15.5 | SMAD5 | 0 | 1 | 1 |
| EP300 | 15.5 | SMAD9 | 0.8 | 1 | 0.603 |
| EP300 | 15.5 | SNW1 | 1.8 | 0.695 | 0.703 |
| HDAC3 | 0.3 | HDAC7 | 0.8 | 1 | 0.992 |
| HDAC3 | 0.3 | NCOR1 | 8.6 | 0.0863 | 1 |
| HDAC3 | 0.3 | NCOR2 | 4.6 | 1 | 0.954 |
| HDAC3 | 0.3 | RBPJ | 0.8 | 1 | 0.992 |
| HDAC3 | 0.3 | SKIL | 3.3 | 1 | 0.967 |
| HDAC3 | 0.3 | SKI | 0.3 | 1 | 0.997 |
| HDAC3 | 0.3 | SMAD1 | 1.3 | 1 | 0.987 |
| HDAC3 | 0.3 | SMAD2 | 1 | 1 | 0.99 |
| HDAC3 | 0.3 | SMAD3 | 1.3 | 1 | 0.987 |
| HDAC3 | 0.3 | SMAD4 | 2 | 1 | 0.98 |
| HDAC3 | 0.3 | SMAD5 | 0 | 1 | 1 |
| HDAC3 | 0.3 | SMAD9 | 0.8 | 1 | 0.992 |
| HDAC3 | 0.3 | SNW1 | 1.8 | 1 | 0.982 |
| HDAC3 | 0.3 | TBL1XR1 | 2 | 1 | 0.98 |
| HDAC3 | 0.3 | TBL1X | 1.3 | 1 | 0.987 |
| HDAC3 | 0.3 | TLE1 | 1.5 | 1 | 0.985 |
| HDAC3 | 0.3 | TLE2 | 0.8 | 1 | 0.992 |
| HDAC3 | 0.3 | TLE3 | 1 | 1 | 0.99 |
| HDAC3 | 0.3 | TLE4 | 1 | 1 | 0.99 |
| HDAC7 | 0.8 | HIF1A | 1.5 | 1 | 0.955 |
| HDAC7 | 0.8 | NCOR1 | 8.6 | 1 | 0.762 |
| HDAC7 | 0.8 | NCOR2 | 4.6 | 0.131 | 0.994 |
| HDAC7 | 0.8 | RBPJ | 0.8 | 1 | 0.977 |
| HDAC7 | 0.8 | SKIL | 3.3 | 1 | 0.904 |
| HDAC7 | 0.8 | SKI | 0.3 | 1 | 0.992 |
| HDAC7 | 0.8 | SMAD1 | 1.3 | 1 | 0.962 |
| HDAC7 | 0.8 | SMAD2 | 1 | 1 | 0.97 |
| HDAC7 | 0.8 | SMAD3 | 1.3 | 1 | 0.962 |
| HDAC7 | 0.8 | SMAD4 | 2 | 1 | 0.94 |
| HDAC7 | 0.8 | SMAD5 | 0 | 1 | 1 |
| HDAC7 | 0.8 | SMAD9 | 0.8 | 1 | 0.977 |
| HDAC7 | 0.8 | SNW1 | 1.8 | 1 | 0.948 |
| HDAC7 | 0.8 | TBL1XR1 | 2 | 1 | 0.94 |
| HDAC7 | 0.8 | TBL1X | 1.3 | 1 | 0.962 |
| HDAC7 | 0.8 | TLE1 | 1.5 | 1 | 0.955 |
| HDAC7 | 0.8 | TLE2 | 0.8 | 1 | 0.977 |
| HDAC7 | 0.8 | TLE3 | 1 | 1 | 0.97 |
| HDAC7 | 0.8 | TLE4 | 1 | 1 | 0.97 |
| HIF1A | 1.5 | SMAD3 | 1.3 | 1 | 0.926 |
| HIF1A | 1.5 | SMAD4 | 2 | 0.117 | 0.995 |
| NCOR1 | 8.6 | NCOR2 | 4.6 | 0.196 | 0.941 |
| NCOR1 | 8.6 | RBPJ | 0.8 | 0.0206 | 0.999 |
| NCOR1 | 8.6 | SKIL | 3.3 | 0.311 | 0.908 |
| NCOR1 | 8.6 | SKI | 0.3 | 1 | 0.914 |
| NCOR1 | 8.6 | SMAD2 | 1 | 1 | 0.696 |
| NCOR1 | 8.6 | SMAD3 | 1.3 | 0.365 | 0.939 |
| NCOR1 | 8.6 | SMAD4 | 2 | 0.146 | 0.976 |
| NCOR1 | 8.6 | SNW1 | 1.8 | 0.471 | 0.885 |
| NCOR1 | 8.6 | TBL1XR1 | 2 | 1 | 0.482 |
| NCOR1 | 8.6 | TBL1X | 1.3 | 1 | 0.635 |
| NCOR2 | 4.6 | RBPJ | 0.8 | 1 | 0.869 |
| NCOR2 | 4.6 | SKIL | 3.3 | 0.114 | 0.983 |
| NCOR2 | 4.6 | SKI | 0.3 | 1 | 0.954 |
| NCOR2 | 4.6 | SMAD2 | 1 | 1 | 0.829 |
| NCOR2 | 4.6 | SMAD3 | 1.3 | 0.209 | 0.982 |
| NCOR2 | 4.6 | SMAD4 | 2 | 1 | 0.686 |
| NCOR2 | 4.6 | SNW1 | 1.8 | 1 | 0.719 |
| NCOR2 | 4.6 | TBL1XR1 | 2 | 1 | 0.686 |
| NCOR2 | 4.6 | TBL1X | 1.3 | 1 | 0.791 |
| RBPJ | 0.8 | SKIL | 3.3 | 0.096 | 0.997 |
| RBPJ | 0.8 | SKI | 0.3 | 1 | 0.992 |
| RBPJ | 0.8 | SNW1 | 1.8 | 1 | 0.948 |
| RBPJ | 0.8 | TBL1XR1 | 2 | 1 | 0.94 |
| RBPJ | 0.8 | TBL1X | 1.3 | 1 | 0.962 |
| RBPJ | 0.8 | TLE1 | 1.5 | 1 | 0.955 |
| RBPJ | 0.8 | TLE2 | 0.8 | 0.0227 | 1 |
| RBPJ | 0.8 | TLE3 | 1 | 1 | 0.97 |
| RBPJ | 0.8 | TLE4 | 1 | 1 | 0.97 |
| SKIL | 3.3 | SMAD1 | 1.3 | 0.155 | 0.99 |
| SKIL | 3.3 | SMAD2 | 1 | 1 | 0.874 |
| SKIL | 3.3 | SMAD3 | 1.3 | 1 | 0.845 |
| SKIL | 3.3 | SMAD4 | 2 | 0.237 | 0.975 |
| SKIL | 3.3 | SMAD5 | 0 | 1 | 1 |
| SKIL | 3.3 | SMAD9 | 0.8 | 1 | 0.904 |
| SKI | 0.3 | SKIL | 3.3 | 1 | 0.967 |
| SKI | 0.3 | SMAD1 | 1.3 | 1 | 0.987 |
| SKI | 0.3 | SMAD2 | 1 | 1 | 0.99 |
| SKI | 0.3 | SMAD3 | 1.3 | 1 | 0.987 |
| SKI | 0.3 | SMAD4 | 2 | 1 | 0.98 |
| SKI | 0.3 | SMAD5 | 0 | 1 | 1 |
| SKI | 0.3 | SMAD9 | 0.8 | 1 | 0.992 |
| SMAD1 | 1.3 | SMAD4 | 2 | 1 | 0.902 |
| SMAD1 | 1.3 | TLE1 | 1.5 | 0.0742 | 0.998 |
| SMAD1 | 1.3 | TLE2 | 0.8 | 1 | 0.962 |
| SMAD1 | 1.3 | TLE3 | 1 | 1 | 0.95 |
| SMAD1 | 1.3 | TLE4 | 1 | 1 | 0.95 |
| SMAD2 | 1 | SMAD3 | 1.3 | 1 | 0.95 |
| SMAD2 | 1 | SMAD4 | 2 | 0.0791 | 0.998 |
| SMAD2 | 1 | TLE1 | 1.5 | 1 | 0.94 |
| SMAD2 | 1 | TLE2 | 0.8 | 1 | 0.97 |
| SMAD2 | 1 | TLE3 | 1 | 1 | 0.96 |
| SMAD2 | 1 | TLE4 | 1 | 1 | 0.96 |
| SMAD3 | 1.3 | SMAD4 | 2 | 1 | 0.902 |
| SMAD3 | 1.3 | TLE1 | 1.5 | 0.0742 | 0.998 |
| SMAD3 | 1.3 | TLE2 | 0.8 | 1 | 0.962 |
| SMAD3 | 1.3 | TLE3 | 1 | 1 | 0.95 |
| SMAD3 | 1.3 | TLE4 | 1 | 1 | 0.95 |
| SMAD4 | 2 | SMAD5 | 0 | 1 | 1 |
| SMAD4 | 2 | SMAD9 | 0.8 | 1 | 0.94 |
| SMAD4 | 2 | TLE1 | 1.5 | 1 | 0.883 |
| SMAD4 | 2 | TLE2 | 0.8 | 1 | 0.94 |
| SMAD4 | 2 | TLE3 | 1 | 1 | 0.921 |
| SMAD4 | 2 | TLE4 | 1 | 1 | 0.921 |
| SMAD5 | 0 | TLE1 | 1.5 | 1 | 1 |
| SMAD5 | 0 | TLE2 | 0.8 | 1 | 1 |
| SMAD5 | 0 | TLE3 | 1 | 1 | 1 |
| SMAD5 | 0 | TLE4 | 1 | 1 | 1 |
| SMAD9 | 0.8 | TLE1 | 1.5 | 1 | 0.955 |
| SMAD9 | 0.8 | TLE2 | 0.8 | 1 | 0.977 |
| SMAD9 | 0.8 | TLE3 | 1 | 1 | 0.97 |
| SMAD9 | 0.8 | TLE4 | 1 | 1 | 0.97 |
| SNW1 | 1.8 | TBL1XR1 | 2 | 1 | 0.865 |
| SNW1 | 1.8 | TBL1X | 1.3 | 1 | 0.914 |
| TBL1X | 1.3 | TBL1XR1 | 2 | 1 | 0.902 |
| TLE1 | 1.5 | TLE2 | 0.8 | 1 | 0.955 |
| TLE1 | 1.5 | TLE3 | 1 | 0.0598 | 0.999 |
| TLE1 | 1.5 | TLE4 | 1 | 0.0598 | 0.999 |
| TLE2 | 0.8 | TLE3 | 1 | 1 | 0.97 |
| TLE2 | 0.8 | TLE4 | 1 | 1 | 0.97 |
| TLE3 | 1 | TLE4 | 1 | 1 | 0.96 |