*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).
| Node 1 | % Mutation Rate (Node 1) |
Node 2 | % Mutation Rate (Node 2) |
P Value (co-occurrence) |
P Value (mutual exclusive) |
|---|---|---|---|---|---|
| ACTB | 4.3 | ACTL6A | 1.5 | 0.234 | 0.976 |
| ACTB | 4.3 | ACTR5 | 0.5 | 1 | 0.915 |
| ACTB | 4.3 | ACTR8 | 1.8 | 0.267 | 0.968 |
| ACTB | 4.3 | CTNNB1 | 3.6 | 1 | 0.534 |
| ACTB | 4.3 | INO80B | 0.3 | 1 | 0.957 |
| ACTB | 4.3 | INO80C | 0 | 1 | 1 |
| ACTB | 4.3 | INO80D | 2 | 0.3 | 0.958 |
| ACTB | 4.3 | INO80E | 1 | 1 | 0.838 |
| ACTB | 4.3 | INO80 | 5.8 | 1 | 0.352 |
| ACTB | 4.3 | MCRS1 | 1.5 | 0.0238 | 0.999 |
| ACTB | 4.3 | NFRKB | 2.3 | 1 | 0.67 |
| ACTB | 4.3 | RUVBL1 | 1.5 | 1 | 0.766 |
| ACTB | 4.3 | RUVBL2 | 0.5 | 1 | 0.915 |
| ACTB | 4.3 | TFPT | 0.8 | 1 | 0.876 |
| ACTB | 4.3 | YY1 | 1.3 | 0.199 | 0.984 |
| ACTL6A | 1.5 | ACTR5 | 0.5 | 1 | 0.97 |
| ACTL6A | 1.5 | ACTR8 | 1.8 | 0.103 | 0.996 |
| ACTL6A | 1.5 | INO80B | 0.3 | 1 | 0.985 |
| ACTL6A | 1.5 | INO80C | 0 | 1 | 1 |
| ACTL6A | 1.5 | INO80D | 2 | 0.117 | 0.995 |
| ACTL6A | 1.5 | INO80E | 1 | 1 | 0.94 |
| ACTL6A | 1.5 | INO80 | 5.8 | 0.305 | 0.958 |
| ACTL6A | 1.5 | MCRS1 | 1.5 | 0.0885 | 0.997 |
| ACTL6A | 1.5 | NFRKB | 2.3 | 0.13 | 0.993 |
| ACTL6A | 1.5 | RUVBL1 | 1.5 | 0.0885 | 0.997 |
| ACTL6A | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| ACTL6A | 1.5 | TCF3 | 0.8 | 1 | 0.955 |
| ACTL6A | 1.5 | TFPT | 0.8 | 1 | 0.955 |
| ACTL6A | 1.5 | YY1 | 1.3 | 1 | 0.926 |
| ACTR5 | 0.5 | ACTR8 | 1.8 | 1 | 0.965 |
| ACTR5 | 0.5 | INO80B | 0.3 | 1 | 0.995 |
| ACTR5 | 0.5 | INO80C | 0 | 1 | 1 |
| ACTR5 | 0.5 | INO80D | 2 | 1 | 0.96 |
| ACTR5 | 0.5 | INO80E | 1 | 1 | 0.98 |
| ACTR5 | 0.5 | INO80 | 5.8 | 1 | 0.887 |
| ACTR5 | 0.5 | MCRS1 | 1.5 | 1 | 0.97 |
| ACTR5 | 0.5 | NFRKB | 2.3 | 0.0452 | 1 |
| ACTR5 | 0.5 | RUVBL1 | 1.5 | 1 | 0.97 |
| ACTR5 | 0.5 | RUVBL2 | 0.5 | 1 | 0.99 |
| ACTR5 | 0.5 | TCF3 | 0.8 | 1 | 0.985 |
| ACTR5 | 0.5 | TFPT | 0.8 | 1 | 0.985 |
| ACTR5 | 0.5 | YY1 | 1.3 | 1 | 0.975 |
| ACTR8 | 1.8 | INO80B | 0.3 | 1 | 0.982 |
| ACTR8 | 1.8 | INO80C | 0 | 1 | 1 |
| ACTR8 | 1.8 | INO80D | 2 | 0.135 | 0.993 |
| ACTR8 | 1.8 | INO80E | 1 | 1 | 0.931 |
| ACTR8 | 1.8 | INO80 | 5.8 | 0.346 | 0.943 |
| ACTR8 | 1.8 | MCRS1 | 1.5 | 0.103 | 0.996 |
| ACTR8 | 1.8 | NFRKB | 2.3 | 0.15 | 0.991 |
| ACTR8 | 1.8 | RUVBL1 | 1.5 | 0.103 | 0.996 |
| ACTR8 | 1.8 | RUVBL2 | 0.5 | 1 | 0.965 |
| ACTR8 | 1.8 | TCF3 | 0.8 | 1 | 0.948 |
| ACTR8 | 1.8 | TFPT | 0.8 | 1 | 0.948 |
| ACTR8 | 1.8 | YY1 | 1.3 | 1 | 0.914 |
| BCL9 | 3.8 | CREBBP | 12.2 | 0.565 | 0.728 |
| BCL9 | 3.8 | CTNNB1 | 3.6 | 1 | 0.575 |
| BCL9 | 3.8 | EP300 | 15.5 | 0.189 | 0.935 |
| BCL9 | 3.8 | INO80 | 5.8 | 0.216 | 0.95 |
| BCL9 | 3.8 | LEF1 | 0.8 | 1 | 0.89 |
| BCL9 | 3.8 | PYGO1 | 1.8 | 1 | 0.76 |
| BCL9 | 3.8 | PYGO2 | 1.5 | 1 | 0.791 |
| BCL9 | 3.8 | SMAD1 | 1.3 | 0.177 | 0.987 |
| BCL9 | 3.8 | SMAD4 | 2 | 0.0332 | 0.998 |
| BCL9 | 3.8 | SMAD5 | 0 | 1 | 1 |
| BCL9 | 3.8 | TCF7L1 | 0 | 1 | 1 |
| BCL9 | 3.8 | TCF7L2 | 0.3 | 1 | 0.962 |
| CREBBP | 12.2 | CTNNB1 | 3.6 | 0.526 | 0.764 |
| CREBBP | 12.2 | EP300 | 15.5 | 0.642 | 0.527 |
| CREBBP | 12.2 | INO80 | 5.8 | 0.549 | 0.697 |
| CREBBP | 12.2 | LEF1 | 0.8 | 0.323 | 0.96 |
| CREBBP | 12.2 | PYGO1 | 1.8 | 1 | 0.4 |
| CREBBP | 12.2 | PYGO2 | 1.5 | 1 | 0.456 |
| CREBBP | 12.2 | SMAD1 | 1.3 | 0.48 | 0.886 |
| CREBBP | 12.2 | SMAD4 | 2 | 0.65 | 0.747 |
| CREBBP | 12.2 | SMAD5 | 0 | 1 | 1 |
| CREBBP | 12.2 | TCF7L1 | 0 | 1 | 1 |
| CREBBP | 12.2 | TCF7L2 | 0.3 | 1 | 0.878 |
| CREBBP | 12.2 | YY1 | 1.3 | 1 | 0.52 |
| CTNNB1 | 3.6 | EP300 | 15.5 | 0.909 | 0.333 |
| CTNNB1 | 3.6 | INO80 | 5.8 | 0.575 | 0.806 |
| CTNNB1 | 3.6 | LEF1 | 0.8 | 1 | 0.897 |
| CTNNB1 | 3.6 | PYGO1 | 1.8 | 1 | 0.775 |
| CTNNB1 | 3.6 | PYGO2 | 1.5 | 1 | 0.804 |
| CTNNB1 | 3.6 | RUVBL1 | 1.5 | 0.196 | 0.984 |
| CTNNB1 | 3.6 | RUVBL2 | 0.5 | 1 | 0.93 |
| CTNNB1 | 3.6 | SMAD1 | 1.3 | 1 | 0.834 |
| CTNNB1 | 3.6 | SMAD4 | 2 | 1 | 0.747 |
| CTNNB1 | 3.6 | SMAD5 | 0 | 1 | 1 |
| CTNNB1 | 3.6 | TCF7L1 | 0 | 1 | 1 |
| CTNNB1 | 3.6 | TCF7L2 | 0.3 | 1 | 0.964 |
| EP300 | 15.5 | INO80 | 5.8 | 0.127 | 0.952 |
| EP300 | 15.5 | LEF1 | 0.8 | 0.397 | 0.936 |
| EP300 | 15.5 | PYGO1 | 1.8 | 1 | 0.305 |
| EP300 | 15.5 | PYGO2 | 1.5 | 0.638 | 0.766 |
| EP300 | 15.5 | SMAD1 | 1.3 | 0.173 | 0.972 |
| EP300 | 15.5 | SMAD4 | 2 | 1 | 0.257 |
| EP300 | 15.5 | SMAD5 | 0 | 1 | 1 |
| EP300 | 15.5 | TCF7L1 | 0 | 1 | 1 |
| EP300 | 15.5 | TCF7L2 | 0.3 | 1 | 0.845 |
| EP300 | 15.5 | YY1 | 1.3 | 0.571 | 0.827 |
| INO80B | 0.3 | INO80C | 0 | 1 | 1 |
| INO80B | 0.3 | INO80D | 2 | 1 | 0.98 |
| INO80B | 0.3 | INO80E | 1 | 1 | 0.99 |
| INO80B | 0.3 | MCRS1 | 1.5 | 1 | 0.985 |
| INO80B | 0.3 | NFRKB | 2.3 | 1 | 0.977 |
| INO80B | 0.3 | RUVBL1 | 1.5 | 1 | 0.985 |
| INO80B | 0.3 | RUVBL2 | 0.5 | 1 | 0.995 |
| INO80B | 0.3 | TCF3 | 0.8 | 1 | 0.992 |
| INO80B | 0.3 | TFPT | 0.8 | 1 | 0.992 |
| INO80B | 0.3 | YY1 | 1.3 | 1 | 0.987 |
| INO80C | 0 | INO80D | 2 | 1 | 1 |
| INO80C | 0 | INO80E | 1 | 1 | 1 |
| INO80C | 0 | MCRS1 | 1.5 | 1 | 1 |
| INO80C | 0 | NFRKB | 2.3 | 1 | 1 |
| INO80C | 0 | RUVBL1 | 1.5 | 1 | 1 |
| INO80C | 0 | RUVBL2 | 0.5 | 1 | 1 |
| INO80C | 0 | TCF3 | 0.8 | 1 | 1 |
| INO80C | 0 | TFPT | 0.8 | 1 | 1 |
| INO80C | 0 | YY1 | 1.3 | 1 | 1 |
| INO80D | 2 | INO80E | 1 | 0.0791 | 0.998 |
| INO80D | 2 | MCRS1 | 1.5 | 0.117 | 0.995 |
| INO80D | 2 | NFRKB | 2.3 | 1 | 0.83 |
| INO80D | 2 | RUVBL1 | 1.5 | 0.117 | 0.995 |
| INO80D | 2 | RUVBL2 | 0.5 | 1 | 0.96 |
| INO80D | 2 | TCF3 | 0.8 | 1 | 0.94 |
| INO80D | 2 | TFPT | 0.8 | 1 | 0.94 |
| INO80D | 2 | YY1 | 1.3 | 1 | 0.902 |
| INO80E | 1 | MCRS1 | 1.5 | 1 | 0.94 |
| INO80E | 1 | NFRKB | 2.3 | 1 | 0.911 |
| INO80E | 1 | RUVBL1 | 1.5 | 1 | 0.94 |
| INO80E | 1 | RUVBL2 | 0.5 | 1 | 0.98 |
| INO80E | 1 | TCF3 | 0.8 | 1 | 0.97 |
| INO80E | 1 | TFPT | 0.8 | 1 | 0.97 |
| INO80E | 1 | YY1 | 1.3 | 1 | 0.95 |
| INO80 | 5.8 | INO80B | 0.3 | 0.0584 | 1 |
| INO80 | 5.8 | INO80C | 0 | 1 | 1 |
| INO80 | 5.8 | INO80D | 2 | 0.0737 | 0.992 |
| INO80 | 5.8 | INO80E | 1 | 1 | 0.785 |
| INO80 | 5.8 | LEF1 | 0.8 | 1 | 0.835 |
| INO80 | 5.8 | MCRS1 | 1.5 | 1 | 0.695 |
| INO80 | 5.8 | NFRKB | 2.3 | 1 | 0.579 |
| INO80 | 5.8 | PYGO1 | 1.8 | 1 | 0.654 |
| INO80 | 5.8 | PYGO2 | 1.5 | 0.305 | 0.958 |
| INO80 | 5.8 | RUVBL1 | 1.5 | 1 | 0.695 |
| INO80 | 5.8 | RUVBL2 | 0.5 | 1 | 0.887 |
| INO80 | 5.8 | SMAD1 | 1.3 | 1 | 0.739 |
| INO80 | 5.8 | SMAD4 | 2 | 0.385 | 0.926 |
| INO80 | 5.8 | SMAD5 | 0 | 1 | 1 |
| INO80 | 5.8 | TCF3 | 0.8 | 1 | 0.835 |
| INO80 | 5.8 | TCF7L1 | 0 | 1 | 1 |
| INO80 | 5.8 | TCF7L2 | 0.3 | 1 | 0.942 |
| INO80 | 5.8 | TFPT | 0.8 | 1 | 0.835 |
| INO80 | 5.8 | YY1 | 1.3 | 1 | 0.739 |
| LEF1 | 0.8 | PYGO1 | 1.8 | 1 | 0.948 |
| LEF1 | 0.8 | PYGO2 | 1.5 | 1 | 0.955 |
| LEF1 | 0.8 | RUVBL1 | 1.5 | 0.0451 | 0.999 |
| LEF1 | 0.8 | SMAD1 | 1.3 | 0.0377 | 1 |
| LEF1 | 0.8 | SMAD4 | 2 | 1 | 0.94 |
| LEF1 | 0.8 | SMAD5 | 0 | 1 | 1 |
| MCRS1 | 1.5 | NFRKB | 2.3 | 1 | 0.87 |
| MCRS1 | 1.5 | RUVBL1 | 1.5 | 1 | 0.911 |
| MCRS1 | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| MCRS1 | 1.5 | TCF3 | 0.8 | 1 | 0.955 |
| MCRS1 | 1.5 | TFPT | 0.8 | 1 | 0.955 |
| MCRS1 | 1.5 | YY1 | 1.3 | 0.0742 | 0.998 |
| NFRKB | 2.3 | RUVBL1 | 1.5 | 0.13 | 0.993 |
| NFRKB | 2.3 | RUVBL2 | 0.5 | 1 | 0.955 |
| NFRKB | 2.3 | TCF3 | 0.8 | 1 | 0.933 |
| NFRKB | 2.3 | TFPT | 0.8 | 0.0671 | 0.999 |
| NFRKB | 2.3 | YY1 | 1.3 | 1 | 0.89 |
| PYGO1 | 1.8 | SMAD1 | 1.3 | 1 | 0.914 |
| PYGO1 | 1.8 | SMAD4 | 2 | 1 | 0.865 |
| PYGO1 | 1.8 | SMAD5 | 0 | 1 | 1 |
| PYGO1 | 1.8 | TCF7L1 | 0 | 1 | 1 |
| PYGO1 | 1.8 | TCF7L2 | 0.3 | 1 | 0.982 |
| PYGO2 | 1.5 | SMAD1 | 1.3 | 1 | 0.926 |
| PYGO2 | 1.5 | SMAD4 | 2 | 1 | 0.883 |
| PYGO2 | 1.5 | SMAD5 | 0 | 1 | 1 |
| PYGO2 | 1.5 | TCF7L1 | 0 | 1 | 1 |
| PYGO2 | 1.5 | TCF7L2 | 0.3 | 1 | 0.985 |
| RUVBL1 | 1.5 | RUVBL2 | 0.5 | 1 | 0.97 |
| RUVBL1 | 1.5 | TCF3 | 0.8 | 1 | 0.955 |
| RUVBL1 | 1.5 | TCF7L1 | 0 | 1 | 1 |
| RUVBL1 | 1.5 | TCF7L2 | 0.3 | 1 | 0.985 |
| RUVBL1 | 1.5 | TFPT | 0.8 | 1 | 0.955 |
| RUVBL1 | 1.5 | YY1 | 1.3 | 1 | 0.926 |
| RUVBL2 | 0.5 | TCF3 | 0.8 | 1 | 0.985 |
| RUVBL2 | 0.5 | TCF7L2 | 0.3 | 1 | 0.995 |
| SMAD1 | 1.3 | SMAD4 | 2 | 1 | 0.902 |
| SMAD1 | 1.3 | TCF7L1 | 0 | 1 | 1 |
| SMAD1 | 1.3 | TCF7L2 | 0.3 | 1 | 0.987 |
| SMAD4 | 2 | SMAD5 | 0 | 1 | 1 |
| SMAD4 | 2 | TCF7L1 | 0 | 1 | 1 |
| SMAD4 | 2 | TCF7L2 | 0.3 | 1 | 0.98 |
| SMAD5 | 0 | TCF7L1 | 0 | 1 | 1 |
| SMAD5 | 0 | TCF7L2 | 0.3 | 1 | 1 |
| TFPT | 0.8 | YY1 | 1.3 | 1 | 0.962 |