*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).


Node 1 % Mutation Rate
(Node 1)
Node 2 % Mutation Rate
(Node 2)
P Value
(co-occurrence)
P Value
(mutual exclusive)
APEX10.3FEN10.810.992
APEX10.3LIG1110.99
APEX10.3PCNA110.99
APEX10.3POLD11.810.982
APEX10.3POLD20.810.992
APEX10.3POLD31.310.987
APEX10.3POLD4011
APEX10.3POLE2110.99
APEX10.3POLE6.610.934
APEX10.3RFC1210.98
APEX10.3RFC21.310.987
APEX10.3RFC30.310.997
APEX10.3RFC42.310.977
APEX10.3RFC5110.99
APEX10.3RPA1011
APEX10.3RPA20.310.997
APEX10.3RPA30.810.992
AQR2.8CCNH0.80.08160.998
AQR2.8CDK71.510.843
AQR2.8CUL4A1.310.867
AQR2.8CUL4B2.510.751
AQR2.8DDB120.01810.999
AQR2.8EP30015.50.5290.766
AQR2.8ERCC10.810.918
AQR2.8ERCC29.60.07940.985
AQR2.8ERCC31.810.819
AQR2.8ERCC41.310.867
AQR2.8ERCC51.810.819
AQR2.8ERCC62.810.729
AQR2.8ERCC80.310.972
AQR2.8GTF2H1110.893
AQR2.8GTF2H2011
AQR2.8GTF2H31.310.867
AQR2.8GTF2H40.310.972
AQR2.8GTF2H5011
AQR2.8HMGN10.510.945
AQR2.8ISY10.310.972
AQR2.8MNAT110.1070.996
AQR2.8PCNA110.893
AQR2.8POLD11.810.819
AQR2.8POLD20.810.918
AQR2.8POLD31.310.867
AQR2.8POLD4011
AQR2.8POLE2110.893
AQR2.8POLE6.60.5330.84
AQR2.8POLK2.810.729
AQR2.8POLR2A2.510.751
AQR2.8POLR2B2.50.2490.972
AQR2.8POLR2C10.1070.996
AQR2.8POLR2D0.310.972
AQR2.8POLR2E0.50.05510.999
AQR2.8POLR2F0.510.945
AQR2.8POLR2G011
AQR2.8POLR2H0.50.05510.999
AQR2.8POLR2I0.510.945
AQR2.8POLR2J011
AQR2.8POLR2K011
AQR2.8POLR2L011
AQR2.8PPIE0.810.918
AQR2.8PRPF191.510.843
AQR2.8RBX10.310.972
AQR2.8RFC1210.796
AQR2.8RFC21.310.867
AQR2.8RFC30.310.972
AQR2.8RFC42.310.773
AQR2.8RFC5110.893
AQR2.8RPA1011
AQR2.8RPA20.310.972
AQR2.8RPA30.810.918
AQR2.8RPS27A0.310.972
AQR2.8TCEA1011
AQR2.8UBA521.310.867
AQR2.8UBB011
AQR2.8UBC1.510.843
AQR2.8USP73.80.3510.939
AQR2.8UVSSA2.80.2710.966
AQR2.8XAB2210.796
AQR2.8XPA0.510.945
AQR2.8ZNF8301.310.867
BARD12.5BRCA15.10.410.914
BARD12.5DNA22.50.2290.977
BARD12.5EXO11.810.834
BARD12.5MLH12.30.0190.999
BARD12.5MSH62.510.771
BARD12.5PCNA110.902
BARD12.5POLR2A2.50.2290.977
BARD12.5RAD511.810.834
BARD12.5RFC21.310.879
BARD12.5RFC30.310.975
BARD12.5RFC42.310.792
BARD12.5RFC5110.902
BARD12.5RPA1011
BARD12.5RPA20.310.975
BARD12.5RPA30.810.926
BARD12.5SUMO10.510.95
BARD12.5XRCC50.310.975
BARD12.5XRCC60.50.05020.999
BRCA15.1CCNH0.810.855
BRCA15.1CDK410.01381
BRCA15.1CDK71.510.73
BRCA15.1DNA22.50.08630.989
BRCA15.1DNMT12.310.623
BRCA15.1ERCC29.60.5940.698
BRCA15.1ERCC31.80.04410.997
BRCA15.1ESR11.30.230.978
BRCA15.1EXO11.810.692
BRCA15.1GTF2H1110.811
BRCA15.1GTF2H2011
BRCA15.1GTF2H31.310.77
BRCA15.1GTF2H40.310.949
BRCA15.1GTF2H5011
BRCA15.1MLH12.310.623
BRCA15.1MNAT1110.811
BRCA15.1MSH22.80.440.898
BRCA15.1MSH62.50.410.914
BRCA15.1PCNA10.1890.986
BRCA15.1POLR2A2.50.410.914
BRCA15.1POLR2B2.50.01070.999
BRCA15.1POLR2C110.811
BRCA15.1POLR2D0.310.949
BRCA15.1POLR2E0.510.901
BRCA15.1POLR2F0.510.901
BRCA15.1POLR2G011
BRCA15.1POLR2H0.510.901
BRCA15.1POLR2I0.510.901
BRCA15.1POLR2J011
BRCA15.1POLR2K011
BRCA15.1POLR2L011
BRCA15.1RAD511.80.3080.956
BRCA15.1RFC1210.657
BRCA15.1RFC21.30.230.978
BRCA15.1RFC30.310.949
BRCA15.1RFC42.310.623
BRCA15.1RFC5110.811
BRCA15.1RPA1011
BRCA15.1RPA20.310.949
BRCA15.1RPA30.810.855
BRCA15.1SUMO10.510.901
BRCA15.1TCEA1011
BRCA15.1VCP110.811
CCNB11CCNB2011
CCNB11CCND1110.96
CCNB11CDK10.310.99
CCNB11CDK20.310.99
CCNB11CDKN1A8.910.688
CCNB11GADD45A0.310.99
CCNB11GADD45B011
CCNB11GADD45G0.310.99
CCNB11PARP12.510.902
CCNB11PCNA110.96
CCNB11POLA1210.921
CCNB11POLD11.810.931
CCNB11POLE6.60.02320.999
CCNB11RFC1210.921
CCNB11RFC21.310.95
CCNB11RPA1011
CCNB11RPA20.310.99
CCNB11RPA30.810.97
CCNB11RPS27A0.310.99
CCNB11TOP11.50.05980.999
CCNB11UBA521.30.050.999
CCNB11UBB011
CCNB11UBC1.510.94
CCNB20CCND1111
CCNB20CDK10.311
CCNB20CDKN1A8.911
CCNB20PCNA111
CCND11CCND31.310.95
CCND11CDK10.310.99
CCND11CDK20.310.99
CCND11CDK4110.96
CCND11CDK50.810.97
CCND11CDKN1A8.910.688
CCND11PCNA110.96
CCND11RPS27A0.310.99
CCND11UBA521.310.95
CCND11UBB011
CCND11UBC1.510.94
CCND31.3CDK4110.95
CCND31.3CDK50.810.962
CCND31.3CDKN1A8.90.3740.935
CCND31.3PCNA110.95
CCNH0.8CDK71.510.955
CCNH0.8CUL4A1.310.962
CCNH0.8CUL4B2.510.926
CCNH0.8DDB120.05980.999
CCNH0.8DDB2210.94
CCNH0.8EP30015.510.603
CCNH0.8ERCC10.810.977
CCNH0.8ERCC29.60.2630.974
CCNH0.8ERCC31.810.948
CCNH0.8ERCC41.310.962
CCNH0.8ERCC51.810.948
CCNH0.8ERCC62.810.918
CCNH0.8ERCC80.310.992
CCNH0.8ESR11.310.962
CCNH0.8GTF2H1110.97
CCNH0.8GTF2H2011
CCNH0.8GTF2H31.310.962
CCNH0.8GTF2H40.310.992
CCNH0.8GTF2H5011
CCNH0.8HMGN10.510.985
CCNH0.8ISY10.310.992
CCNH0.8MNAT110.03021
CCNH0.8PARP12.510.926
CCNH0.8PARP20.80.02271
CCNH0.8PCNA110.97
CCNH0.8POLD11.810.948
CCNH0.8POLD20.810.977
CCNH0.8POLD31.310.962
CCNH0.8POLD4011
CCNH0.8POLE2110.97
CCNH0.8POLE6.610.814
CCNH0.8POLK2.810.918
CCNH0.8POLR2A2.510.926
CCNH0.8POLR2B2.510.926
CCNH0.8POLR2C110.97
CCNH0.8POLR2D0.310.992
CCNH0.8POLR2E0.50.01521
CCNH0.8POLR2F0.510.985
CCNH0.8POLR2G011
CCNH0.8POLR2H0.510.985
CCNH0.8POLR2I0.510.985
CCNH0.8POLR2J011
CCNH0.8POLR2K011
CCNH0.8POLR2L011
CCNH0.8PPIE0.810.977
CCNH0.8PRPF191.510.955
CCNH0.8RARA1.510.955
CCNH0.8RBX10.310.992
CCNH0.8RFC1210.94
CCNH0.8RFC21.310.962
CCNH0.8RFC30.310.992
CCNH0.8RFC42.310.933
CCNH0.8RFC5110.97
CCNH0.8RPA1011
CCNH0.8RPA20.310.992
CCNH0.8RPA30.810.977
CCNH0.8RPS27A0.310.992
CCNH0.8TCEA1011
CCNH0.8UBA521.310.962
CCNH0.8UBB011
CCNH0.8UBC1.510.955
CCNH0.8USP73.80.110.996
CCNH0.8UVSSA2.810.918
CCNH0.8XAB2210.94
CCNH0.8XPA0.510.985
CCNH0.8ZNF8301.310.962
CDK10.3CDK20.310.997
CDK10.3CDKN1A8.910.911
CDK10.3GADD45A0.310.997
CDK10.3GADD45B011
CDK10.3GADD45G0.310.997
CDK10.3PARP12.50.02541
CDK10.3PCNA110.99
CDK10.3POLA1210.98
CDK10.3POLD11.810.982
CDK10.3POLE6.610.934
CDK10.3RFC1210.98
CDK10.3RFC21.310.987
CDK10.3RPA1011
CDK10.3RPA20.310.997
CDK10.3RPA30.810.992
CDK10.3RPS27A0.310.997
CDK10.3TOP11.510.985
CDK10.3UBA521.30.01271
CDK10.3UBB011
CDK10.3UBC1.510.985
CDK20.3CDKN1A8.910.911
CDK20.3LIG1110.99
CDK20.3MLH12.310.977
CDK20.3PARP12.510.975
CDK20.3PCNA110.99
CDK20.3POLA1210.98
CDK20.3POLA22.810.972
CDK20.3POLD11.810.982
CDK20.3POLE6.610.934
CDK20.3RBX10.310.997
CDK20.3RFC1210.98
CDK20.3RFC21.310.987
CDK20.3RFC30.310.997
CDK20.3RFC42.310.977
CDK20.3RFC5110.99
CDK20.3RPA1011
CDK20.3RPA20.310.997
CDK20.3RPA30.810.992
CDK20.3RPS27A0.310.997
CDK20.3TOP11.510.985
CDK20.3UBA521.310.987
CDK20.3UBB011
CDK20.3UBC1.510.985
CDK41CDKN1A8.90.3120.959
CDK41PCNA10.04011
CDK41RAD511.810.931
CDK41RPA1011
CDK41RPA20.310.99
CDK41RPA30.810.97
CDK50.8CDKN1A8.910.756
CDK50.8PCNA110.97
CDK71.5CUL4A1.310.926
CDK71.5CUL4B2.50.1440.992
CDK71.5DDB1210.883
CDK71.5DDB220.1170.995
CDK71.5EP30015.50.05010.994
CDK71.5ERCC10.810.955
CDK71.5ERCC29.610.542
CDK71.5ERCC31.80.003931
CDK71.5ERCC41.30.07420.998
CDK71.5ERCC51.80.1030.996
CDK71.5ERCC62.80.1570.99
CDK71.5ERCC80.310.985
CDK71.5ESR11.310.926
CDK71.5GTF2H1110.94
CDK71.5GTF2H2011
CDK71.5GTF2H31.310.926
CDK71.5GTF2H40.310.985
CDK71.5GTF2H5011
CDK71.5HMGN10.510.97
CDK71.5ISY10.310.985
CDK71.5MNAT110.001151
CDK71.5PARP12.510.856
CDK71.5PARP20.810.955
CDK71.5PCNA110.94
CDK71.5POLD11.810.897
CDK71.5POLD20.810.955
CDK71.5POLD31.30.07420.998
CDK71.5POLD4011
CDK71.5POLE2110.94
CDK71.5POLE6.60.3380.947
CDK71.5POLK2.80.1570.99
CDK71.5POLR2A2.510.856
CDK71.5POLR2B2.510.856
CDK71.5POLR2C10.05980.999
CDK71.5POLR2D0.310.985
CDK71.5POLR2E0.510.97
CDK71.5POLR2F0.510.97
CDK71.5POLR2G011
CDK71.5POLR2H0.510.97
CDK71.5POLR2I0.510.97
CDK71.5POLR2J011
CDK71.5POLR2K011
CDK71.5POLR2L011
CDK71.5PPIE0.810.955
CDK71.5PRPF191.50.08850.997
CDK71.5RBX10.30.01521
CDK71.5RFC120.1170.995
CDK71.5RFC21.310.926
CDK71.5RFC30.310.985
CDK71.5RFC42.310.87
CDK71.5RFC5110.94
CDK71.5RPA1011
CDK71.5RPA20.310.985
CDK71.5RPA30.810.955
CDK71.5RPS27A0.310.985
CDK71.5TCEA1011
CDK71.5UBA521.310.926
CDK71.5UBB011
CDK71.5UBC1.510.911
CDK71.5USP73.80.01860.999
CDK71.5UVSSA2.810.843
CDK71.5XAB220.1170.995
CDK71.5XPA0.510.97
CDK71.5ZNF8301.30.07420.998
CDKN1A8.9PCNA110.688
CDKN1A8.9RPS27A0.310.911
CDKN1A8.9UBA521.310.626
CDKN1A8.9UBB011
CDKN1A8.9UBC1.510.57
CHD1L1CUL4A1.310.95
CHD1L1CUL4B2.510.902
CHD1L1DDB1210.921
CHD1L1DDB2210.921
CHD1L1ERCC10.810.97
CHD1L1ERCC29.610.665
CHD1L1ERCC31.810.931
CHD1L1ERCC41.310.95
CHD1L1ERCC51.810.931
CHD1L1GTF2H1110.96
CHD1L1GTF2H2011
CHD1L1GTF2H31.310.95
CHD1L1GTF2H40.310.99
CHD1L1GTF2H5011
CHD1L1PARP12.510.902
CHD1L1PARP20.810.97
CHD1L1PCNA110.96
CHD1L1POLD11.810.931
CHD1L1POLD20.80.03021
CHD1L1POLD31.310.95
CHD1L1POLD4011
CHD1L1POLE2110.96
CHD1L1POLE6.610.76
CHD1L1POLK2.810.893
CHD1L1RBX10.310.99
CHD1L1RFC1210.921
CHD1L1RFC21.310.95
CHD1L1RFC30.310.99
CHD1L1RFC42.310.911
CHD1L1RFC5110.96
CHD1L1RPA1011
CHD1L1RPA20.310.99
CHD1L1RPA30.810.97
CHD1L1RPS27A0.310.99
CHD1L1SUMO10.510.98
CHD1L1UBA521.310.95
CHD1L1UBB011
CHD1L1UBC1.510.94
CHD1L1XPA0.510.98
CHTF181PCNA110.96
CHTF181POLH210.921
CHTF181RFC21.310.95
CHTF181RFC30.310.99
CHTF181RFC42.310.911
CHTF181RFC5110.96
CUL4A1.3CUL4B2.510.879
CUL4A1.3DDB1210.902
CUL4A1.3DDB2210.902
CUL4A1.3DTL1.510.926
CUL4A1.3EP30015.50.5710.827
CUL4A1.3ERCC10.810.962
CUL4A1.3ERCC29.60.07520.993
CUL4A1.3ERCC31.80.08620.997
CUL4A1.3ERCC41.310.938
CUL4A1.3ERCC51.810.914
CUL4A1.3ERCC62.810.867
CUL4A1.3ERCC80.310.987
CUL4A1.3GTF2H1110.95
CUL4A1.3GTF2H2011
CUL4A1.3GTF2H31.310.938
CUL4A1.3GTF2H40.310.987
CUL4A1.3GTF2H5011
CUL4A1.3HMGN10.510.975
CUL4A1.3ISY10.310.987
CUL4A1.3MNAT1110.95
CUL4A1.3PARP12.50.1210.994
CUL4A1.3PARP20.810.962
CUL4A1.3PCNA10.050.999
CUL4A1.3POLD11.810.914
CUL4A1.3POLD20.810.962
CUL4A1.3POLD31.310.938
CUL4A1.3POLD4011
CUL4A1.3POLE2110.95
CUL4A1.3POLE6.610.71
CUL4A1.3POLK2.80.1330.993
CUL4A1.3POLR2A2.50.1210.994
CUL4A1.3POLR2B2.510.879
CUL4A1.3POLR2C110.95
CUL4A1.3POLR2D0.310.987
CUL4A1.3POLR2E0.510.975
CUL4A1.3POLR2F0.510.975
CUL4A1.3POLR2G011
CUL4A1.3POLR2H0.510.975
CUL4A1.3POLR2I0.510.975
CUL4A1.3POLR2J011
CUL4A1.3POLR2K011
CUL4A1.3POLR2L011
CUL4A1.3PPIE0.810.962
CUL4A1.3PRPF191.510.926
CUL4A1.3RBX10.310.987
CUL4A1.3RFC1210.902
CUL4A1.3RFC21.310.938
CUL4A1.3RFC30.310.987
CUL4A1.3RFC42.30.110.996
CUL4A1.3RFC510.050.999
CUL4A1.3RPA1011
CUL4A1.3RPA20.310.987
CUL4A1.3RPA30.810.962
CUL4A1.3RPS27A0.310.987
CUL4A1.3SUMO10.510.975
CUL4A1.3TCEA1011
CUL4A1.3UBA521.310.938
CUL4A1.3UBB011
CUL4A1.3UBC1.510.926
CUL4A1.3USP73.80.1770.987
CUL4A1.3UVSSA2.810.867
CUL4A1.3XAB220.0980.996
CUL4A1.3XPA0.510.975
CUL4A1.3ZNF8301.310.938
CUL4B2.5DDB1210.813
CUL4B2.5DDB220.1870.985
CUL4B2.5DTL1.50.008251
CUL4B2.5EP30015.50.190.947
CUL4B2.5ERCC10.810.926
CUL4B2.5ERCC29.60.06180.99
CUL4B2.5ERCC31.80.1660.989
CUL4B2.5ERCC41.310.879
CUL4B2.5ERCC51.810.834
CUL4B2.5ERCC62.80.001761
CUL4B2.5ERCC80.310.975
CUL4B2.5GTF2H1110.902
CUL4B2.5GTF2H2011
CUL4B2.5GTF2H31.310.879
CUL4B2.5GTF2H40.310.975
CUL4B2.5GTF2H5011
CUL4B2.5HMGN10.510.95
CUL4B2.5ISY10.310.975
CUL4B2.5MNAT1110.902
CUL4B2.5PARP12.50.02340.999
CUL4B2.5PARP20.810.926
CUL4B2.5PCNA110.902
CUL4B2.5POLD11.80.1660.989
CUL4B2.5POLD20.810.926
CUL4B2.5POLD31.310.879
CUL4B2.5POLD4011
CUL4B2.5POLE2110.902
CUL4B2.5POLE6.60.1360.977
CUL4B2.5POLK2.810.751
CUL4B2.5POLR2A2.50.2290.977
CUL4B2.5POLR2B2.510.771
CUL4B2.5POLR2C110.902
CUL4B2.5POLR2D0.310.975
CUL4B2.5POLR2E0.510.95
CUL4B2.5POLR2F0.510.95
CUL4B2.5POLR2G011
CUL4B2.5POLR2H0.510.95
CUL4B2.5POLR2I0.510.95
CUL4B2.5POLR2J011
CUL4B2.5POLR2K011
CUL4B2.5POLR2L011
CUL4B2.5PPIE0.810.926
CUL4B2.5PRPF191.50.1440.992
CUL4B2.5RBX10.310.975
CUL4B2.5RFC120.1870.985
CUL4B2.5RFC21.310.879
CUL4B2.5RFC30.310.975
CUL4B2.5RFC42.30.2080.981
CUL4B2.5RFC5110.902
CUL4B2.5RPA1011
CUL4B2.5RPA20.310.975
CUL4B2.5RPA30.810.926
CUL4B2.5RPS27A0.310.975
CUL4B2.5SUMO10.510.95
CUL4B2.5TCEA1011
CUL4B2.5UBA521.310.879
CUL4B2.5UBB011
CUL4B2.5UBC1.510.856
CUL4B2.5USP73.80.3250.949
CUL4B2.5UVSSA2.810.751
CUL4B2.5XAB2210.813
CUL4B2.5XPA0.510.95
CUL4B2.5ZNF8301.310.879
DDB12DDB2210.847
DDB12DTL1.510.883
DDB12EP30015.50.7430.642
DDB12ERCC10.810.94
DDB12ERCC29.60.03310.996
DDB12ERCC31.810.865
DDB12ERCC41.310.902
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PCNA1PMS11.810.931
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UBA521.3UBB011
UBA521.3UBC1.510.926
UBA521.3UBE2B0.510.975
UBA521.3UBE2L60.510.975
UBA521.3UFD1L0.510.975
UBA521.3USP101.510.926
UBA521.3USP11.310.938
UBA521.3USP73.810.823
UBA521.3UVSSA2.810.867
UBA521.3VCP110.95
UBA521.3XAB2210.902
UBA521.3XPA0.510.975
UBA521.3ZBTB321.810.914
UBA521.3ZNF8301.310.938
UBB0UBC1.511
UBB0UBE2B0.511
UBB0UBE2L60.511
UBB0UFD1L0.511
UBB0USP101.511
UBB0USP11.311
UBB0USP73.811
UBB0UVSSA2.811
UBB0VCP111
UBB0XAB2211
UBB0XPA0.511
UBB0ZBTB321.811
UBB0ZNF8301.311
UBC1.5UBE2B0.510.97
UBC1.5UBE2L60.510.97
UBC1.5UFD1L0.510.97
UBC1.5USP101.510.911
UBC1.5USP11.310.926
UBC1.5USP73.810.791
UBC1.5UVSSA2.810.843
UBC1.5VCP110.94
UBC1.5XAB2210.883
UBC1.5XPA0.510.97
UBC1.5ZBTB321.80.1030.996
UBC1.5ZNF8301.310.926
UFD1L0.5VCP110.98
USP11.3ZBTB321.810.914
USP73.8UVSSA2.810.649
USP73.8XAB220.03320.998
USP73.8XPA0.510.925
USP73.8ZNF8301.310.823
UVSSA2.8XAB2210.796
UVSSA2.8XPA0.510.945
UVSSA2.8ZNF8301.310.867
XAB22XPA0.510.96
XAB22ZNF8301.310.902
XPA0.5ZNF8301.310.975
XRCC50.3XRCC60.510.995