*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).

Node 1	% Mutation Rate (Node 1)	Node 2	% Mutation Rate (Node 2)	P Value (co-occurrence)	P Value (mutual exclusive)
ASH2L	0.3	CCNY	0.5	1	0.995
ASH2L	0.3	DPY30	0.3	1	0.997
ASH2L	0.3	HCFC1	1	0.0102	1
ASH2L	0.3	HDAC1	1	1	0.99
ASH2L	0.3	HDAC2	0.8	1	0.992
ASH2L	0.3	HSP90AA1	5.3	1	0.947
ASH2L	0.3	HSP90AB1	2.5	1	0.975
ASH2L	0.3	HSPA4	0.8	1	0.992
ASH2L	0.3	HSPA5	2	1	0.98
ASH2L	0.3	HSPA8	2.3	1	0.977
ASH2L	0.3	KAT8	1.5	1	0.985
ASH2L	0.3	KMT2A	11.2	0.112	1
ASH2L	0.3	KMT2D	28.9	0.289	1
ASH2L	0.3	OGT	1.3	1	0.987
ASH2L	0.3	RBBP4	1	1	0.99
ASH2L	0.3	RBBP5	1	1	0.99
ASH2L	0.3	RBBP7	1.3	1	0.987
ASH2L	0.3	RNF2	1.3	1	0.987
ASH2L	0.3	SAP30	0.8	1	0.992
ASH2L	0.3	SETD1A	2.3	1	0.977
ASH2L	0.3	SIN3A	2.3	0.0228	1
ASH2L	0.3	SIN3B	1.3	1	0.987
ASH2L	0.3	SP1	2.3	1	0.977
ASH2L	0.3	SUDS3	0	1	1
ASH2L	0.3	TAF1	2.5	1	0.975
ASH2L	0.3	TAF6	1.5	1	0.985
ASH2L	0.3	TAF9	1	1	0.99
ASH2L	0.3	WDR5	0.3	1	0.997
ASH2L	0.3	WDR82	0.3	1	0.997
CCNY	0.5	RBBP5	1	1	0.98
CCNY	0.5	SETD1A	2.3	1	0.955
CCNY	0.5	WDR5	0.3	1	0.995
CCNY	0.5	WDR82	0.3	1	0.995
DPY30	0.3	HDAC1	1	1	0.99
DPY30	0.3	KMT2A	11.2	1	0.888
DPY30	0.3	KMT2D	28.9	1	0.711
DPY30	0.3	RBBP5	1	1	0.99
DPY30	0.3	SETD1A	2.3	1	0.977
DPY30	0.3	WDR5	0.3	1	0.997
HCFC1	1	HDAC1	1	1	0.96
HCFC1	1	HDAC2	0.8	1	0.97
HCFC1	1	HSP90AA1	5.3	0.197	0.985
HCFC1	1	HSP90AB1	2.5	1	0.902
HCFC1	1	HSPA4	0.8	1	0.97
HCFC1	1	HSPA5	2	1	0.921
HCFC1	1	HSPA8	2.3	1	0.911
HCFC1	1	KAT8	1.5	1	0.94
HCFC1	1	KMT2A	11.2	0.378	0.937
HCFC1	1	OGT	1.3	1	0.95
HCFC1	1	RBBP4	1	1	0.96
HCFC1	1	RBBP5	1	1	0.96
HCFC1	1	RBBP7	1.3	1	0.95
HCFC1	1	RNF2	1.3	1	0.95
HCFC1	1	SAP30	0.8	1	0.97
HCFC1	1	SETD1A	2.3	1	0.911
HCFC1	1	SIN3A	2.3	0.0886	0.997
HCFC1	1	SIN3B	1.3	1	0.95
HCFC1	1	SP1	2.3	1	0.911
HCFC1	1	SUDS3	0	1	1
HCFC1	1	TAF1	2.5	1	0.902
HCFC1	1	TAF6	1.5	1	0.94
HCFC1	1	TAF9	1	1	0.96
HCFC1	1	WDR5	0.3	1	0.99
HDAC1	1	HDAC2	0.8	1	0.97
HDAC1	1	HSP90AA1	5.3	1	0.803
HDAC1	1	HSP90AB1	2.5	1	0.902
HDAC1	1	HSPA4	0.8	1	0.97
HDAC1	1	HSPA5	2	1	0.921
HDAC1	1	HSPA8	2.3	1	0.911
HDAC1	1	KMT2A	11.2	0.378	0.937
HDAC1	1	OGT	1.3	1	0.95
HDAC1	1	RBBP4	1	1	0.96
HDAC1	1	RBBP5	1	1	0.96
HDAC1	1	RBBP7	1.3	1	0.95
HDAC1	1	SAP30	0.8	1	0.97
HDAC1	1	SETD1A	2.3	1	0.911
HDAC1	1	SIN3A	2.3	1	0.911
HDAC1	1	SIN3B	1.3	1	0.95
HDAC1	1	SP1	2.3	1	0.911
HDAC1	1	SUDS3	0	1	1
HDAC1	1	TAF1	2.5	1	0.902
HDAC1	1	TAF6	1.5	0.0598	0.999
HDAC1	1	TAF9	1	0.0401	1
HDAC1	1	WDR5	0.3	1	0.99
HDAC2	0.8	HSP90AA1	5.3	0.152	0.992
HDAC2	0.8	HSP90AB1	2.5	1	0.926
HDAC2	0.8	HSPA4	0.8	1	0.977
HDAC2	0.8	HSPA5	2	1	0.94
HDAC2	0.8	HSPA8	2.3	1	0.933
HDAC2	0.8	KMT2A	11.2	1	0.7
HDAC2	0.8	OGT	1.3	1	0.962
HDAC2	0.8	RBBP4	1	1	0.97
HDAC2	0.8	RBBP5	1	1	0.97
HDAC2	0.8	RBBP7	1.3	1	0.962
HDAC2	0.8	SAP30	0.8	1	0.977
HDAC2	0.8	SETD1A	2.3	1	0.933
HDAC2	0.8	SIN3A	2.3	1	0.933
HDAC2	0.8	SIN3B	1.3	1	0.962
HDAC2	0.8	SP1	2.3	1	0.933
HDAC2	0.8	SUDS3	0	1	1
HDAC2	0.8	TAF1	2.5	1	0.926
HDAC2	0.8	TAF6	1.5	1	0.955
HDAC2	0.8	TAF9	1	1	0.97
HDAC2	0.8	WDR5	0.3	1	0.992
HSP90AA1	5.3	HSP90AB1	2.5	1	0.574
HSP90AA1	5.3	HSPA4	0.8	1	0.848
HSP90AA1	5.3	HSPA5	2	0.357	0.938
HSP90AA1	5.3	HSPA8	2.3	1	0.608
HSP90AA1	5.3	OGT	1.3	1	0.759
HSP90AA1	5.3	RBBP4	1	1	0.803
HSP90AA1	5.3	RBBP7	1.3	1	0.759
HSP90AA1	5.3	SAP30	0.8	1	0.848
HSP90AA1	5.3	SETD1A	2.3	1	0.608
HSP90AA1	5.3	SIN3A	2.3	0.392	0.922
HSP90AA1	5.3	SIN3B	1.3	0.241	0.975
HSP90AA1	5.3	SP1	2.3	0.392	0.922
HSP90AA1	5.3	SUDS3	0	1	1
HSP90AA1	5.3	WDR5	0.3	1	0.947
HSP90AB1	2.5	HSPA4	0.8	1	0.926
HSP90AB1	2.5	HSPA5	2	0.187	0.985
HSP90AB1	2.5	HSPA8	2.3	1	0.792
HSP90AB1	2.5	OGT	1.3	1	0.879
HSP90AB1	2.5	RBBP4	1	1	0.902
HSP90AB1	2.5	RBBP7	1.3	1	0.879
HSP90AB1	2.5	SAP30	0.8	0.0744	0.998
HSP90AB1	2.5	SETD1A	2.3	0.208	0.981
HSP90AB1	2.5	SIN3A	2.3	0.019	0.999
HSP90AB1	2.5	SIN3B	1.3	1	0.879
HSP90AB1	2.5	SP1	2.3	0.208	0.981
HSP90AB1	2.5	SUDS3	0	1	1
HSP90AB1	2.5	WDR5	0.3	1	0.975
HSPA4	0.8	HSPA5	2	0.0598	0.999
HSPA4	0.8	HSPA8	2.3	0.0671	0.999
HSPA4	0.8	KAT8	1.5	1	0.955
HSPA4	0.8	KMT2A	11.2	1	0.7
HSPA4	0.8	OGT	1.3	1	0.962
HSPA4	0.8	RBBP4	1	1	0.97
HSPA4	0.8	RBBP5	1	1	0.97
HSPA4	0.8	RBBP7	1.3	1	0.962
HSPA4	0.8	RNF2	1.3	1	0.962
HSPA4	0.8	SAP30	0.8	1	0.977
HSPA4	0.8	SETD1A	2.3	1	0.933
HSPA4	0.8	SIN3A	2.3	1	0.933
HSPA4	0.8	SIN3B	1.3	1	0.962
HSPA4	0.8	SP1	2.3	1	0.933
HSPA4	0.8	SUDS3	0	1	1
HSPA4	0.8	TAF1	2.5	1	0.926
HSPA4	0.8	TAF6	1.5	1	0.955
HSPA4	0.8	TAF9	1	1	0.97
HSPA4	0.8	WDR5	0.3	1	0.992
HSPA5	2	HSPA8	2.3	1	0.83
HSPA5	2	OGT	1.3	1	0.902
HSPA5	2	RBBP4	1	1	0.921
HSPA5	2	RBBP7	1.3	0.098	0.996
HSPA5	2	RNF2	1.3	1	0.902
HSPA5	2	SAP30	0.8	0.0598	0.999
HSPA5	2	SETD1A	2.3	1	0.83
HSPA5	2	SIN3A	2.3	1	0.83
HSPA5	2	SIN3B	1.3	0.098	0.996
HSPA5	2	SP1	2.3	0.17	0.988
HSPA5	2	SUDS3	0	1	1
HSPA5	2	WDR5	0.3	1	0.98
HSPA8	2.3	OGT	1.3	1	0.89
HSPA8	2.3	RBBP4	1	1	0.911
HSPA8	2.3	RBBP7	1.3	0.11	0.996
HSPA8	2.3	RNF2	1.3	1	0.89
HSPA8	2.3	SAP30	0.8	1	0.933
HSPA8	2.3	SETD1A	2.3	1	0.81
HSPA8	2.3	SIN3A	2.3	1	0.81
HSPA8	2.3	SIN3B	1.3	0.11	0.996
HSPA8	2.3	SP1	2.3	1	0.81
HSPA8	2.3	SUDS3	0	1	1
HSPA8	2.3	WDR5	0.3	1	0.977
KAT8	1.5	KMT2A	11.2	0.511	0.863
KAT8	1.5	KMT2D	28.9	0.873	0.442
KAT8	1.5	OGT	1.3	1	0.926
KAT8	1.5	RBBP5	1	1	0.94
KAT8	1.5	RNF2	1.3	1	0.926
KAT8	1.5	SETD1A	2.3	1	0.87
KAT8	1.5	TAF1	2.5	1	0.856
KAT8	1.5	TAF6	1.5	1	0.911
KAT8	1.5	TAF9	1	1	0.94
KAT8	1.5	WDR5	0.3	1	0.985
KMT2A	11.2	KMT2D	28.9	0.0938	0.951
KMT2A	11.2	RBBP4	1	1	0.622
KMT2A	11.2	RBBP5	1	0.378	0.937
KMT2A	11.2	RBBP7	1.3	0.449	0.902
KMT2A	11.2	RNF2	1.3	0.449	0.902
KMT2A	11.2	SAP30	0.8	1	0.7
KMT2A	11.2	SETD1A	2.3	0.265	0.932
KMT2A	11.2	SIN3A	2.3	0.66	0.735
KMT2A	11.2	TAF1	2.5	0.309	0.911
KMT2A	11.2	TAF6	1.5	0.137	0.98
KMT2A	11.2	TAF9	1	0.00482	1
KMT2A	11.2	WDR5	0.3	1	0.888
KMT2D	28.9	RBBP5	1	0.747	0.671
KMT2D	28.9	RNF2	1.3	0.821	0.55
KMT2D	28.9	SETD1A	2.3	0.51	0.756
KMT2D	28.9	TAF1	2.5	0.59	0.679
KMT2D	28.9	TAF6	1.5	0.235	0.939
KMT2D	28.9	TAF9	1	0.747	0.671
KMT2D	28.9	WDR5	0.3	0.289	1
OGT	1.3	RBBP4	1	1	0.95
OGT	1.3	RBBP7	1.3	1	0.938
OGT	1.3	SAP30	0.8	1	0.962
OGT	1.3	SETD1A	2.3	1	0.89
OGT	1.3	SIN3A	2.3	1	0.89
OGT	1.3	SIN3B	1.3	1	0.938
OGT	1.3	SP1	2.3	1	0.89
OGT	1.3	SUDS3	0	1	1
OGT	1.3	WDR5	0.3	1	0.987
RBBP4	1	RBBP5	1	1	0.96
RBBP4	1	RBBP7	1.3	1	0.95
RBBP4	1	SAP30	0.8	1	0.97
RBBP4	1	SETD1A	2.3	1	0.911
RBBP4	1	SIN3A	2.3	0.00272	1
RBBP4	1	SIN3B	1.3	1	0.95
RBBP4	1	SP1	2.3	1	0.911
RBBP4	1	SUDS3	0	1	1
RBBP4	1	TAF1	2.5	1	0.902
RBBP4	1	TAF6	1.5	1	0.94
RBBP4	1	TAF9	1	1	0.96
RBBP4	1	WDR5	0.3	1	0.99
RBBP5	1	RBBP7	1.3	1	0.95
RBBP5	1	RNF2	1.3	1	0.95
RBBP5	1	SAP30	0.8	1	0.97
RBBP5	1	SETD1A	2.3	1	0.911
RBBP5	1	SIN3A	2.3	1	0.911
RBBP5	1	TAF1	2.5	1	0.902
RBBP5	1	TAF6	1.5	0.0598	0.999
RBBP5	1	TAF9	1	1	0.96
RBBP5	1	WDR5	0.3	1	0.99
RBBP5	1	WDR82	0.3	1	0.99
RBBP7	1.3	SAP30	0.8	1	0.962
RBBP7	1.3	SETD1A	2.3	1	0.89
RBBP7	1.3	SIN3A	2.3	1	0.89
RBBP7	1.3	SIN3B	1.3	0.0622	0.999
RBBP7	1.3	SP1	2.3	1	0.89
RBBP7	1.3	SUDS3	0	1	1
RBBP7	1.3	TAF1	2.5	1	0.879
RBBP7	1.3	TAF6	1.5	0.0742	0.998
RBBP7	1.3	TAF9	1	1	0.95
RBBP7	1.3	WDR5	0.3	1	0.987
RNF2	1.3	SETD1A	2.3	1	0.89
RNF2	1.3	TAF1	2.5	1	0.879
RNF2	1.3	TAF6	1.5	1	0.926
RNF2	1.3	TAF9	1	1	0.95
RNF2	1.3	WDR5	0.3	1	0.987
SAP30	0.8	SETD1A	2.3	1	0.933
SAP30	0.8	SIN3A	2.3	0.0671	0.999
SAP30	0.8	SIN3B	1.3	1	0.962
SAP30	0.8	SP1	2.3	0.0671	0.999
SAP30	0.8	SUDS3	0	1	1
SAP30	0.8	TAF1	2.5	1	0.926
SAP30	0.8	TAF6	1.5	1	0.955
SAP30	0.8	TAF9	1	1	0.97
SAP30	0.8	WDR5	0.3	1	0.992
SETD1A	2.3	SIN3A	2.3	0.19	0.985
SETD1A	2.3	SIN3B	1.3	1	0.89
SETD1A	2.3	SP1	2.3	1	0.81
SETD1A	2.3	SUDS3	0	1	1
SETD1A	2.3	TAF1	2.5	1	0.792
SETD1A	2.3	TAF6	1.5	0.13	0.993
SETD1A	2.3	TAF9	1	1	0.911
SETD1A	2.3	WDR5	0.3	1	0.977
SETD1A	2.3	WDR82	0.3	0.0228	1
SIN3A	2.3	SIN3B	1.3	1	0.89
SIN3A	2.3	SP1	2.3	1	0.81
SIN3A	2.3	SUDS3	0	1	1
SIN3A	2.3	TAF1	2.5	1	0.792
SIN3A	2.3	TAF6	1.5	1	0.87
SIN3A	2.3	TAF9	1	0.0886	0.997
SIN3A	2.3	WDR5	0.3	1	0.977
SIN3B	1.3	SP1	2.3	1	0.89
SIN3B	1.3	SUDS3	0	1	1
SIN3B	1.3	WDR5	0.3	1	0.987
SP1	2.3	SUDS3	0	1	1
SP1	2.3	TAF6	1.5	1	0.87
SP1	2.3	TAF9	1	1	0.911
SP1	2.3	WDR5	0.3	1	0.977
SUDS3	0	WDR5	0.3	1	1
TAF1	2.5	TAF6	1.5	1	0.856
TAF1	2.5	TAF9	1	1	0.902
TAF1	2.5	WDR5	0.3	1	0.975
TAF6	1.5	TAF9	1	1	0.94
TAF6	1.5	WDR5	0.3	1	0.985
TAF9	1	WDR5	0.3	1	0.99
WDR5	0.3	WDR82	0.3	1	0.997