*The size of the node in the network represents the mutation rate of the cancer type selected in the above box. Mouse over on the node would show its mutation rate and first neighbors. For edge color, blue means co-occurrence while red for mutual exclusive (p value < 0.05, Fisher's exact test).
| Node 1 | % Mutation Rate (Node 1) |
Node 2 | % Mutation Rate (Node 2) |
P Value (co-occurrence) |
P Value (mutual exclusive) |
|---|---|---|---|---|---|
| BRCA2 | 9.1 | HDAC1 | 1 | 1 | 0.681 |
| BRCA2 | 9.1 | HDAC2 | 0.8 | 0.25 | 0.977 |
| BRCA2 | 9.1 | HMG20B | 0.8 | 0.25 | 0.977 |
| BRCA2 | 9.1 | KDM1A | 1.8 | 0.491 | 0.873 |
| BRCA2 | 9.1 | PHF21A | 1.3 | 0.382 | 0.932 |
| BRCA2 | 9.1 | RCOR1 | 0.8 | 1 | 0.75 |
| CHD3 | 3.6 | CHD4 | 6.1 | 0.591 | 0.793 |
| CHD3 | 3.6 | GSE1 | 1.5 | 0.196 | 0.984 |
| CHD3 | 3.6 | GTF2I | 4.1 | 1 | 0.554 |
| CHD3 | 3.6 | HDAC1 | 1 | 1 | 0.865 |
| CHD3 | 3.6 | HDAC2 | 0.8 | 1 | 0.897 |
| CHD3 | 3.6 | HMG20B | 0.8 | 1 | 0.897 |
| CHD3 | 3.6 | KDM1A | 1.8 | 1 | 0.775 |
| CHD3 | 3.6 | MTA1 | 1.3 | 1 | 0.834 |
| CHD3 | 3.6 | MTA2 | 2.3 | 0.0366 | 0.997 |
| CHD3 | 3.6 | PHF21A | 1.3 | 1 | 0.834 |
| CHD3 | 3.6 | RBBP4 | 1 | 0.135 | 0.993 |
| CHD3 | 3.6 | RBBP7 | 1.3 | 1 | 0.834 |
| CHD3 | 3.6 | RCOR1 | 0.8 | 0.103 | 0.997 |
| CHD3 | 3.6 | SIN3A | 2.3 | 0.0366 | 0.997 |
| CHD3 | 3.6 | SIN3B | 1.3 | 1 | 0.834 |
| CHD3 | 3.6 | ZMYM2 | 2 | 1 | 0.747 |
| CHD3 | 3.6 | ZMYM3 | 2.5 | 1 | 0.693 |
| CHD4 | 6.1 | GSE1 | 1.5 | 0.0459 | 0.996 |
| CHD4 | 6.1 | GTF2I | 4.1 | 0.642 | 0.746 |
| CHD4 | 6.1 | HDAC1 | 1 | 1 | 0.777 |
| CHD4 | 6.1 | HDAC2 | 0.8 | 0.172 | 0.99 |
| CHD4 | 6.1 | HMG20B | 0.8 | 0.172 | 0.99 |
| CHD4 | 6.1 | KDM1A | 1.8 | 1 | 0.642 |
| CHD4 | 6.1 | MTA1 | 1.3 | 1 | 0.729 |
| CHD4 | 6.1 | MTA2 | 2.3 | 0.435 | 0.901 |
| CHD4 | 6.1 | PHF21A | 1.3 | 0.271 | 0.968 |
| CHD4 | 6.1 | RBBP4 | 1 | 0.0198 | 0.999 |
| CHD4 | 6.1 | RBBP7 | 1.3 | 1 | 0.729 |
| CHD4 | 6.1 | RCOR1 | 0.8 | 1 | 0.828 |
| CHD4 | 6.1 | SIN3A | 2.3 | 0.435 | 0.901 |
| CHD4 | 6.1 | SIN3B | 1.3 | 0.271 | 0.968 |
| CHD4 | 6.1 | ZMYM2 | 2 | 0.398 | 0.92 |
| CHD4 | 6.1 | ZMYM3 | 2.5 | 0.018 | 0.998 |
| CTBP1 | 1 | HDAC1 | 1 | 1 | 0.96 |
| CTBP1 | 1 | HDAC2 | 0.8 | 1 | 0.97 |
| CTBP1 | 1 | HMG20A | 1 | 1 | 0.96 |
| CTBP1 | 1 | HMG20B | 0.8 | 1 | 0.97 |
| CTBP1 | 1 | HSPA1A | 0.8 | 1 | 0.97 |
| CTBP1 | 1 | HSPA1B | 0.3 | 1 | 0.99 |
| CTBP1 | 1 | HSPA7 | 0 | 1 | 1 |
| CTBP1 | 1 | KDM1A | 1.8 | 1 | 0.931 |
| CTBP1 | 1 | PHF21A | 1.3 | 1 | 0.95 |
| CTBP1 | 1 | PHF21B | 0 | 1 | 1 |
| CTBP1 | 1 | RBBP4 | 1 | 1 | 0.96 |
| CTBP1 | 1 | RBBP7 | 1.3 | 1 | 0.95 |
| CTBP1 | 1 | RCOR1 | 0.8 | 1 | 0.97 |
| CTBP1 | 1 | RCOR3 | 1 | 1 | 0.96 |
| CTBP1 | 1 | RREB1 | 3.8 | 1 | 0.856 |
| CTBP1 | 1 | SIN3A | 2.3 | 1 | 0.911 |
| CTBP1 | 1 | SIN3B | 1.3 | 1 | 0.95 |
| CTBP1 | 1 | ZMYM2 | 2 | 1 | 0.921 |
| CTBP1 | 1 | ZNF217 | 3 | 1 | 0.883 |
| CTBP1 | 1 | ZNF516 | 2 | 1 | 0.921 |
| GSE1 | 1.5 | GTF2I | 4.1 | 0.221 | 0.979 |
| GSE1 | 1.5 | HDAC1 | 1 | 1 | 0.94 |
| GSE1 | 1.5 | HDAC2 | 0.8 | 1 | 0.955 |
| GSE1 | 1.5 | HMG20B | 0.8 | 0.0451 | 0.999 |
| GSE1 | 1.5 | KDM1A | 1.8 | 1 | 0.897 |
| GSE1 | 1.5 | MTA1 | 1.3 | 1 | 0.926 |
| GSE1 | 1.5 | MTA2 | 2.3 | 1 | 0.87 |
| GSE1 | 1.5 | PHF21A | 1.3 | 0.0742 | 0.998 |
| GSE1 | 1.5 | RBBP4 | 1 | 1 | 0.94 |
| GSE1 | 1.5 | RBBP7 | 1.3 | 1 | 0.926 |
| GSE1 | 1.5 | RCOR1 | 0.8 | 1 | 0.955 |
| GSE1 | 1.5 | SIN3A | 2.3 | 1 | 0.87 |
| GSE1 | 1.5 | SIN3B | 1.3 | 1 | 0.926 |
| GSE1 | 1.5 | ZMYM2 | 2 | 1 | 0.883 |
| GSE1 | 1.5 | ZMYM3 | 2.5 | 1 | 0.856 |
| GSE1 | 1.5 | ZNF217 | 3 | 0.17 | 0.988 |
| GSE1 | 1.5 | ZNF516 | 2 | 1 | 0.883 |
| GTF2I | 4.1 | HDAC1 | 1 | 0.00886 | 1 |
| GTF2I | 4.1 | HDAC2 | 0.8 | 1 | 0.883 |
| GTF2I | 4.1 | HMG20B | 0.8 | 1 | 0.883 |
| GTF2I | 4.1 | KDM1A | 1.8 | 0.254 | 0.971 |
| GTF2I | 4.1 | MTA1 | 1.3 | 1 | 0.812 |
| GTF2I | 4.1 | MTA2 | 2.3 | 0.314 | 0.953 |
| GTF2I | 4.1 | PHF21A | 1.3 | 0.188 | 0.986 |
| GTF2I | 4.1 | RBBP4 | 1 | 0.153 | 0.991 |
| GTF2I | 4.1 | RBBP7 | 1.3 | 0.188 | 0.986 |
| GTF2I | 4.1 | RCOR1 | 0.8 | 1 | 0.883 |
| GTF2I | 4.1 | SIN3A | 2.3 | 1 | 0.686 |
| GTF2I | 4.1 | SIN3B | 1.3 | 0.188 | 0.986 |
| GTF2I | 4.1 | ZMYM2 | 2 | 0.284 | 0.962 |
| GTF2I | 4.1 | ZMYM3 | 2.5 | 1 | 0.657 |
| GTF2I | 4.1 | ZNF217 | 3 | 0.0805 | 0.99 |
| HDAC1 | 1 | HDAC2 | 0.8 | 1 | 0.97 |
| HDAC1 | 1 | HMG20A | 1 | 1 | 0.96 |
| HDAC1 | 1 | HMG20B | 0.8 | 1 | 0.97 |
| HDAC1 | 1 | HSPA1A | 0.8 | 1 | 0.97 |
| HDAC1 | 1 | HSPA1B | 0.3 | 1 | 0.99 |
| HDAC1 | 1 | HSPA7 | 0 | 1 | 1 |
| HDAC1 | 1 | KDM1A | 1.8 | 1 | 0.931 |
| HDAC1 | 1 | MTA1 | 1.3 | 1 | 0.95 |
| HDAC1 | 1 | MTA2 | 2.3 | 1 | 0.911 |
| HDAC1 | 1 | PHF21A | 1.3 | 1 | 0.95 |
| HDAC1 | 1 | PHF21B | 0 | 1 | 1 |
| HDAC1 | 1 | RBBP4 | 1 | 1 | 0.96 |
| HDAC1 | 1 | RBBP7 | 1.3 | 1 | 0.95 |
| HDAC1 | 1 | RCOR1 | 0.8 | 1 | 0.97 |
| HDAC1 | 1 | RCOR3 | 1 | 1 | 0.96 |
| HDAC1 | 1 | RREB1 | 3.8 | 1 | 0.856 |
| HDAC1 | 1 | SIN3A | 2.3 | 1 | 0.911 |
| HDAC1 | 1 | SIN3B | 1.3 | 1 | 0.95 |
| HDAC1 | 1 | ZMYM2 | 2 | 1 | 0.921 |
| HDAC1 | 1 | ZMYM3 | 2.5 | 1 | 0.902 |
| HDAC1 | 1 | ZNF217 | 3 | 0.117 | 0.995 |
| HDAC1 | 1 | ZNF516 | 2 | 1 | 0.921 |
| HDAC2 | 0.8 | HMG20B | 0.8 | 1 | 0.977 |
| HDAC2 | 0.8 | KDM1A | 1.8 | 1 | 0.948 |
| HDAC2 | 0.8 | MTA1 | 1.3 | 1 | 0.962 |
| HDAC2 | 0.8 | MTA2 | 2.3 | 1 | 0.933 |
| HDAC2 | 0.8 | PHF21A | 1.3 | 1 | 0.962 |
| HDAC2 | 0.8 | RBBP4 | 1 | 1 | 0.97 |
| HDAC2 | 0.8 | RBBP7 | 1.3 | 1 | 0.962 |
| HDAC2 | 0.8 | RCOR1 | 0.8 | 1 | 0.977 |
| HDAC2 | 0.8 | RCOR3 | 1 | 1 | 0.97 |
| HDAC2 | 0.8 | RREB1 | 3.8 | 1 | 0.89 |
| HDAC2 | 0.8 | SIN3A | 2.3 | 1 | 0.933 |
| HDAC2 | 0.8 | SIN3B | 1.3 | 1 | 0.962 |
| HDAC2 | 0.8 | ZMYM2 | 2 | 1 | 0.94 |
| HDAC2 | 0.8 | ZMYM3 | 2.5 | 1 | 0.926 |
| HDAC2 | 0.8 | ZNF217 | 3 | 1 | 0.911 |
| HDAC2 | 0.8 | ZNF516 | 2 | 1 | 0.94 |
| HMG20A | 1 | HMG20B | 0.8 | 0.0302 | 1 |
| HMG20A | 1 | HSPA1A | 0.8 | 1 | 0.97 |
| HMG20A | 1 | HSPA1B | 0.3 | 1 | 0.99 |
| HMG20A | 1 | HSPA7 | 0 | 1 | 1 |
| HMG20A | 1 | KDM1A | 1.8 | 1 | 0.931 |
| HMG20A | 1 | PHF21A | 1.3 | 1 | 0.95 |
| HMG20A | 1 | PHF21B | 0 | 1 | 1 |
| HMG20A | 1 | RCOR1 | 0.8 | 1 | 0.97 |
| HMG20A | 1 | RCOR3 | 1 | 1 | 0.96 |
| HMG20A | 1 | RREB1 | 3.8 | 0.144 | 0.992 |
| HMG20A | 1 | ZMYM2 | 2 | 1 | 0.921 |
| HMG20A | 1 | ZNF217 | 3 | 1 | 0.883 |
| HMG20B | 0.8 | HSPA1A | 0.8 | 1 | 0.977 |
| HMG20B | 0.8 | HSPA1B | 0.3 | 1 | 0.992 |
| HMG20B | 0.8 | HSPA7 | 0 | 1 | 1 |
| HMG20B | 0.8 | KDM1A | 1.8 | 1 | 0.948 |
| HMG20B | 0.8 | MTA1 | 1.3 | 1 | 0.962 |
| HMG20B | 0.8 | MTA2 | 2.3 | 0.0671 | 0.999 |
| HMG20B | 0.8 | PHF21A | 1.3 | 0.0377 | 1 |
| HMG20B | 0.8 | PHF21B | 0 | 1 | 1 |
| HMG20B | 0.8 | RBBP4 | 1 | 1 | 0.97 |
| HMG20B | 0.8 | RBBP7 | 1.3 | 1 | 0.962 |
| HMG20B | 0.8 | RCOR1 | 0.8 | 1 | 0.977 |
| HMG20B | 0.8 | RCOR3 | 1 | 1 | 0.97 |
| HMG20B | 0.8 | RREB1 | 3.8 | 1 | 0.89 |
| HMG20B | 0.8 | SIN3A | 2.3 | 1 | 0.933 |
| HMG20B | 0.8 | SIN3B | 1.3 | 1 | 0.962 |
| HMG20B | 0.8 | ZMYM2 | 2 | 1 | 0.94 |
| HMG20B | 0.8 | ZMYM3 | 2.5 | 1 | 0.926 |
| HMG20B | 0.8 | ZNF217 | 3 | 0.0888 | 0.997 |
| HMG20B | 0.8 | ZNF516 | 2 | 1 | 0.94 |
| HSPA1A | 0.8 | HSPA1B | 0.3 | 1 | 0.992 |
| HSPA1A | 0.8 | KDM1A | 1.8 | 1 | 0.948 |
| HSPA1A | 0.8 | PHF21A | 1.3 | 1 | 0.962 |
| HSPA1A | 0.8 | PHF21B | 0 | 1 | 1 |
| HSPA1A | 0.8 | RCOR1 | 0.8 | 1 | 0.977 |
| HSPA1A | 0.8 | RCOR3 | 1 | 1 | 0.97 |
| HSPA1A | 0.8 | RREB1 | 3.8 | 1 | 0.89 |
| HSPA1A | 0.8 | ZMYM2 | 2 | 1 | 0.94 |
| HSPA1A | 0.8 | ZNF217 | 3 | 1 | 0.911 |
| HSPA1B | 0.3 | KDM1A | 1.8 | 1 | 0.982 |
| HSPA1B | 0.3 | PHF21A | 1.3 | 1 | 0.987 |
| HSPA1B | 0.3 | PHF21B | 0 | 1 | 1 |
| HSPA1B | 0.3 | RCOR1 | 0.8 | 1 | 0.992 |
| HSPA1B | 0.3 | RCOR3 | 1 | 1 | 0.99 |
| HSPA1B | 0.3 | RREB1 | 3.8 | 1 | 0.962 |
| HSPA1B | 0.3 | ZMYM2 | 2 | 1 | 0.98 |
| HSPA1B | 0.3 | ZNF217 | 3 | 1 | 0.97 |
| HSPA7 | 0 | KDM1A | 1.8 | 1 | 1 |
| HSPA7 | 0 | PHF21A | 1.3 | 1 | 1 |
| HSPA7 | 0 | PHF21B | 0 | 1 | 1 |
| HSPA7 | 0 | RCOR1 | 0.8 | 1 | 1 |
| HSPA7 | 0 | RCOR3 | 1 | 1 | 1 |
| HSPA7 | 0 | RREB1 | 3.8 | 1 | 1 |
| HSPA7 | 0 | ZMYM2 | 2 | 1 | 1 |
| HSPA7 | 0 | ZNF217 | 3 | 1 | 1 |
| KDM1A | 1.8 | MTA1 | 1.3 | 1 | 0.914 |
| KDM1A | 1.8 | MTA2 | 2.3 | 1 | 0.85 |
| KDM1A | 1.8 | PHF21A | 1.3 | 1 | 0.914 |
| KDM1A | 1.8 | PHF21B | 0 | 1 | 1 |
| KDM1A | 1.8 | RBBP4 | 1 | 1 | 0.931 |
| KDM1A | 1.8 | RBBP7 | 1.3 | 1 | 0.914 |
| KDM1A | 1.8 | RCOR1 | 0.8 | 1 | 0.948 |
| KDM1A | 1.8 | RCOR3 | 1 | 1 | 0.931 |
| KDM1A | 1.8 | RREB1 | 3.8 | 1 | 0.76 |
| KDM1A | 1.8 | SIN3A | 2.3 | 1 | 0.85 |
| KDM1A | 1.8 | SIN3B | 1.3 | 1 | 0.914 |
| KDM1A | 1.8 | ZMYM2 | 2 | 1 | 0.865 |
| KDM1A | 1.8 | ZMYM3 | 2.5 | 1 | 0.834 |
| KDM1A | 1.8 | ZNF217 | 3 | 1 | 0.804 |
| KDM1A | 1.8 | ZNF516 | 2 | 1 | 0.865 |
| MTA1 | 1.3 | MTA2 | 2.3 | 1 | 0.89 |
| MTA1 | 1.3 | PHF21A | 1.3 | 1 | 0.938 |
| MTA1 | 1.3 | RBBP4 | 1 | 1 | 0.95 |
| MTA1 | 1.3 | RBBP7 | 1.3 | 1 | 0.938 |
| MTA1 | 1.3 | RCOR1 | 0.8 | 1 | 0.962 |
| MTA1 | 1.3 | SIN3A | 2.3 | 1 | 0.89 |
| MTA1 | 1.3 | SIN3B | 1.3 | 1 | 0.938 |
| MTA1 | 1.3 | ZMYM2 | 2 | 1 | 0.902 |
| MTA1 | 1.3 | ZMYM3 | 2.5 | 1 | 0.879 |
| MTA2 | 2.3 | PHF21A | 1.3 | 1 | 0.89 |
| MTA2 | 2.3 | RBBP4 | 1 | 0.0886 | 0.997 |
| MTA2 | 2.3 | RBBP7 | 1.3 | 1 | 0.89 |
| MTA2 | 2.3 | RCOR1 | 0.8 | 1 | 0.933 |
| MTA2 | 2.3 | SIN3A | 2.3 | 0.19 | 0.985 |
| MTA2 | 2.3 | SIN3B | 1.3 | 1 | 0.89 |
| MTA2 | 2.3 | ZMYM2 | 2 | 1 | 0.83 |
| MTA2 | 2.3 | ZMYM3 | 2.5 | 1 | 0.792 |
| PHF21A | 1.3 | PHF21B | 0 | 1 | 1 |
| PHF21A | 1.3 | RBBP4 | 1 | 1 | 0.95 |
| PHF21A | 1.3 | RBBP7 | 1.3 | 1 | 0.938 |
| PHF21A | 1.3 | RCOR1 | 0.8 | 1 | 0.962 |
| PHF21A | 1.3 | RCOR3 | 1 | 1 | 0.95 |
| PHF21A | 1.3 | RREB1 | 3.8 | 1 | 0.823 |
| PHF21A | 1.3 | SIN3A | 2.3 | 1 | 0.89 |
| PHF21A | 1.3 | SIN3B | 1.3 | 0.0622 | 0.999 |
| PHF21A | 1.3 | ZMYM2 | 2 | 1 | 0.902 |
| PHF21A | 1.3 | ZMYM3 | 2.5 | 1 | 0.879 |
| PHF21A | 1.3 | ZNF217 | 3 | 0.144 | 0.992 |
| PHF21A | 1.3 | ZNF516 | 2 | 0.098 | 0.996 |
| PHF21B | 0 | RCOR1 | 0.8 | 1 | 1 |
| PHF21B | 0 | RCOR3 | 1 | 1 | 1 |
| PHF21B | 0 | RREB1 | 3.8 | 1 | 1 |
| PHF21B | 0 | ZMYM2 | 2 | 1 | 1 |
| PHF21B | 0 | ZNF217 | 3 | 1 | 1 |
| RBBP4 | 1 | RBBP7 | 1.3 | 1 | 0.95 |
| RBBP4 | 1 | RCOR1 | 0.8 | 1 | 0.97 |
| RBBP4 | 1 | SIN3A | 2.3 | 0.00272 | 1 |
| RBBP4 | 1 | SIN3B | 1.3 | 1 | 0.95 |
| RBBP4 | 1 | ZMYM2 | 2 | 1 | 0.921 |
| RBBP4 | 1 | ZMYM3 | 2.5 | 0.0981 | 0.997 |
| RBBP7 | 1.3 | RCOR1 | 0.8 | 1 | 0.962 |
| RBBP7 | 1.3 | SIN3A | 2.3 | 1 | 0.89 |
| RBBP7 | 1.3 | SIN3B | 1.3 | 0.0622 | 0.999 |
| RBBP7 | 1.3 | ZMYM2 | 2 | 0.098 | 0.996 |
| RBBP7 | 1.3 | ZMYM3 | 2.5 | 1 | 0.879 |
| RCOR1 | 0.8 | RCOR3 | 1 | 1 | 0.97 |
| RCOR1 | 0.8 | RREB1 | 3.8 | 0.11 | 0.996 |
| RCOR1 | 0.8 | SIN3A | 2.3 | 1 | 0.933 |
| RCOR1 | 0.8 | SIN3B | 1.3 | 1 | 0.962 |
| RCOR1 | 0.8 | ZMYM2 | 2 | 1 | 0.94 |
| RCOR1 | 0.8 | ZMYM3 | 2.5 | 0.0744 | 0.998 |
| RCOR1 | 0.8 | ZNF217 | 3 | 1 | 0.911 |
| RCOR1 | 0.8 | ZNF516 | 2 | 1 | 0.94 |
| RCOR3 | 1 | RREB1 | 3.8 | 1 | 0.856 |
| RCOR3 | 1 | ZMYM2 | 2 | 1 | 0.921 |
| RCOR3 | 1 | ZNF217 | 3 | 1 | 0.883 |
| RCOR3 | 1 | ZNF516 | 2 | 1 | 0.921 |
| RREB1 | 3.8 | ZMYM2 | 2 | 1 | 0.731 |
| RREB1 | 3.8 | ZNF217 | 3 | 0.377 | 0.928 |
| RREB1 | 3.8 | ZNF516 | 2 | 0.0332 | 0.998 |
| SIN3A | 2.3 | SIN3B | 1.3 | 1 | 0.89 |
| SIN3A | 2.3 | ZMYM2 | 2 | 0.17 | 0.988 |
| SIN3A | 2.3 | ZMYM3 | 2.5 | 0.019 | 0.999 |
| SIN3B | 1.3 | ZMYM2 | 2 | 0.098 | 0.996 |
| SIN3B | 1.3 | ZMYM3 | 2.5 | 1 | 0.879 |
| ZMYM2 | 2 | ZMYM3 | 2.5 | 0.187 | 0.985 |
| ZMYM2 | 2 | ZNF217 | 3 | 1 | 0.779 |
| ZMYM2 | 2 | ZNF516 | 2 | 1 | 0.847 |
| ZMYM3 | 2.5 | ZNF217 | 3 | 0.269 | 0.967 |
| ZNF217 | 3 | ZNF516 | 2 | 0.221 | 0.978 |