Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Breast | D352H | Missense | 1 |
| Central nervous system | E125E | Silent | 1 |
| Endometrium | F3F | Silent | 1 |
| Endometrium | L248I | Missense | 1 |
| Haematopoietic and lymphoid tissue | S442S | Silent | 1 |
| Large intestine | M107I | Missense | 1 |
| Large intestine | P444P | Silent | 1 |
| Large intestine | V183A | Missense | 1 |
| Liver | T283S | Missense | 1 |
| Lung | A319D | Missense | 1 |
| Lung | A330G | Missense | 1 |
| Lung | E360Q | Missense | 1 |
| Lung | H331L | Missense | 1 |
| Lung | K4R | Missense | 1 |
| Lung | Q134H | Missense | 1 |
| Lung | R74K | Missense | 1 |
| Lung | S181S | Silent | 1 |
| Lung | S265F | Missense | 1 |
| Lung | V7L | Missense | 1 |
| Ovary | R342H | Missense | 1 |
| Pancreas | K105T | Missense | 1 |
| Soft tissue | R342H | Missense | 1 |
| Upper aerodigestive tract | D135D | Silent | 1 |
| Upper aerodigestive tract | I163I | Silent | 1 |
| Upper aerodigestive tract | L111L | Silent | 1 |
| Upper aerodigestive tract | L176L | Silent | 1 |
| Upper aerodigestive tract | P117P | Silent | 1 |
| Upper aerodigestive tract | Q186Q | Silent | 1 |
| Upper aerodigestive tract | Q187Q | Silent | 1 |
| Urinary tract | D433H | Missense | 1 |
| Urinary tract | E486Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 5.3 | 0 |
| Central nervous system | 52 | 8.3 | 0 | 0 |
| Endometrium | 27 | 8.3 | 5.3 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 8.3 | 0 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 8.3 | 10.5 | 0 |
| Liver | 27 | 0 | 5.3 | 0 |
| Lung | 174 | 8.3 | 47.4 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 5.3 | 0 |
| Pancreas | 44 | 0 | 5.3 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 5.3 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 58.3 | 0 | 0 |
| Urinary tract | 24 | 0 | 10.5 | 0 |