Cancer Type	Mutation	Mutation Type	# Sample
Endometrium	M860T	Missense	2
Large intestine	L629R	Missense	2
Urinary tract	P609A	Missense	2
Breast	E2381K	Missense	1
Breast	K1175E	Missense	1
Breast	P667L	Missense	1
Breast	S890L	Missense	1
Central nervous system	E2281*	Nonsense	1
Central nervous system	N1321K	Missense	1
Endometrium	D379Y	Missense	1
Endometrium	P2299L	Missense	1
Endometrium	R1339M	Missense	1
Endometrium	R1372I	Missense	1
Endometrium	R1481W	Missense	1
Endometrium	S76P	Missense	1
Endometrium	T1146N	Missense	1
Haematopoietic and lymphoid tissue	E687K	Missense	1
Haematopoietic and lymphoid tissue	K17K	Silent	1
Haematopoietic and lymphoid tissue	M2230T	Missense	1
Haematopoietic and lymphoid tissue	P130P	Silent	1
Haematopoietic and lymphoid tissue	R211C	Missense	1
Haematopoietic and lymphoid tissue	R246C	Missense	1
Haematopoietic and lymphoid tissue	S336P	Missense	1
Kidney	K826R	Missense	1
Large intestine	D852E	Missense	1
Large intestine	E431V	Missense	1
Large intestine	H2252R	Missense	1
Large intestine	K762N	Missense	1
Large intestine	K778E	Missense	1
Large intestine	K869N	Missense	1
Large intestine	L192S	Missense	1
Large intestine	N2202Y	Missense	1
Large intestine	P592H	Missense	1
Large intestine	P667L	Missense	1
Large intestine	Q2421*	Nonsense	1
Large intestine	R1138I	Missense	1
Large intestine	R1426*	Nonsense	1
Large intestine	R2474H	Missense	1
Large intestine	S2379N	Missense	1
Large intestine	S26S	Silent	1
Lung	I1208M	Missense	1
Lung	K1176M	Missense	1
Lung	K1600N	Missense	1
Lung	K581N	Missense	1
Lung	K688N	Missense	1
Lung	M1668I	Missense	1
Lung	M366I	Missense	1
Lung	N1321S	Missense	1
Lung	N1705Y	Missense	1
Lung	P609A	Missense	1
Lung	P83P	Silent	1
Lung	Q1874P	Missense	1
Lung	S1116C	Missense	1
Lung	S1944N	Missense	1
Lung	T2007L	Missense	1
Oesophagus	S84L	Missense	1
Oesophagus	T172I	Missense	1
Ovary	D2216H	Missense	1
Ovary	I2390V	Missense	1
Ovary	P995L	Missense	1
Ovary	R2059M	Missense	1
Ovary	S2355*	Nonsense	1
Pancreas	S1470F	Missense	1
Salivary gland	Q539E	Missense	1
Skin	L2056I	Missense	1
Skin	L595F	Missense	1
Soft tissue	C1595*	Nonsense	1
Soft tissue	S54A	Missense	1
Stomach	E1413D	Missense	1
Stomach	T591I	Missense	1
Thyroid	E63K	Missense	1
Upper aerodigestive tract	E1279*	Nonsense	1
Upper aerodigestive tract	E155D	Missense	1
Upper aerodigestive tract	E679K	Missense	1
Upper aerodigestive tract	Q129Q	Silent	1
Upper aerodigestive tract	S510F	Missense	1
Upper aerodigestive tract	T154A	Missense	1
Urinary tract	S1980C	Missense	1

Mutational percentage of Silent,  Missense and  Nonsense for various cancer cell lines

Tissue Type	# Cell Line	% Silent	% Missense	% Nonsense
Autonomic ganglia	17	0	0	0
Biliary tract	7	0	0	0
Bone	25	0	0	0
Breast	58	0	5.7	0
Central nervous system	52	0	1.4	16.7
Endometrium	27	0	12.9	0
Haematopoietic and lymphoid tissue	178	40	7.1	0
Kidney	22	0	1.4	0
Large intestine	57	20	21.4	33.3
Liver	27	0	0	0
Lung	174	20	20	0
Oesophagus	25	0	2.9	0
Ovary	50	0	5.7	16.7
Pancreas	44	0	1.4	0
Pleura	10	0	0	0
Prostate	7	0	0	0
Salivary gland	2	0	1.4	0
Skin	60	0	2.9	0
Small intestine	1	0	0	0
Soft tissue	20	0	1.4	16.7
Stomach	38	0	2.9	0
Thyroid	12	0	1.4	0
Upper aerodigestive tract	30	20	5.7	16.7
Urinary tract	24	0	4.3	0