Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Endometrium | L250F | Missense | 2 |
| Breast | T178S | Missense | 1 |
| Central nervous system | E724D | Missense | 1 |
| Central nervous system | S288C | Missense | 1 |
| Endometrium | P472L | Missense | 1 |
| Endometrium | T386I | Missense | 1 |
| Haematopoietic and lymphoid tissue | D833Y | Missense | 1 |
| Large intestine | G144D | Missense | 1 |
| Large intestine | P211L | Missense | 1 |
| Large intestine | Q923H | Missense | 1 |
| Large intestine | R900C | Missense | 1 |
| Large intestine | R969W | Missense | 1 |
| Lung | A402S | Missense | 1 |
| Lung | Q1095* | Nonsense | 1 |
| Pancreas | V767I | Missense | 1 |
| Skin | S447F | Missense | 1 |
| Soft tissue | A573T | Missense | 1 |
| Stomach | P394H | Missense | 1 |
| Stomach | R1051C | Missense | 1 |
| Urinary tract | P1034S | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 5 | 0 |
| Central nervous system | 52 | 0 | 10 | 0 |
| Endometrium | 27 | 0 | 20 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 5 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 25 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 5 | 100 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 5 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 5 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 5 | 0 |
| Stomach | 38 | 0 | 10 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 5 | 0 |