Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Endometrium | R60Q | Missense | 2 |
| Large intestine | T517M | Missense | 2 |
| Breast | L463V | Missense | 1 |
| Breast | Q261* | Nonsense | 1 |
| Endometrium | G13D | Missense | 1 |
| Endometrium | P175S | Missense | 1 |
| Endometrium | R417M | Missense | 1 |
| Endometrium | V447I | Missense | 1 |
| Haematopoietic and lymphoid tissue | I263M | Missense | 1 |
| Haematopoietic and lymphoid tissue | L437P | Missense | 1 |
| Haematopoietic and lymphoid tissue | R383H | Missense | 1 |
| Kidney | E31K | Missense | 1 |
| Kidney | S287* | Nonsense | 1 |
| Kidney | Y33D | Missense | 1 |
| Large intestine | G307D | Missense | 1 |
| Large intestine | N79S | Missense | 1 |
| Large intestine | P522T | Missense | 1 |
| Large intestine | R208Q | Missense | 1 |
| Large intestine | R508C | Missense | 1 |
| Large intestine | S482L | Missense | 1 |
| Large intestine | V19M | Missense | 1 |
| Lung | A644V | Missense | 1 |
| Lung | G178V | Missense | 1 |
| Lung | G500D | Missense | 1 |
| Lung | R512L | Missense | 1 |
| Pleura | A95D | Missense | 1 |
| Urinary tract | V523I | Missense | 1 |
| Urinary tract | Y401* | Nonsense | 1 |
| Urinary tract | Y401D | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 3.6 | 33.3 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 21.4 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 10.7 | 0 |
| Kidney | 22 | 0 | 7.1 | 33.3 |
| Large intestine | 57 | 0 | 32.1 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 14.3 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 3.6 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 7.1 | 33.3 |