Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | P750L | Missense | 2 |
| Breast | E844Q | Missense | 1 |
| Breast | H740Y | Missense | 1 |
| Breast | Q36* | Nonsense | 1 |
| Breast | T573K | Missense | 1 |
| Endometrium | A122V | Missense | 1 |
| Endometrium | A751T | Missense | 1 |
| Endometrium | C357Y | Missense | 1 |
| Endometrium | E460K | Missense | 1 |
| Endometrium | N44D | Missense | 1 |
| Endometrium | Q245R | Missense | 1 |
| Large intestine | A1203T | Missense | 1 |
| Large intestine | A1268V | Missense | 1 |
| Large intestine | E451G | Missense | 1 |
| Large intestine | E460G | Missense | 1 |
| Large intestine | N852H | Missense | 1 |
| Large intestine | Q235* | Nonsense | 1 |
| Large intestine | R1256W | Missense | 1 |
| Large intestine | R616W | Missense | 1 |
| Large intestine | W120* | Nonsense | 1 |
| Liver | E704V | Missense | 1 |
| Lung | A202G | Missense | 1 |
| Lung | R410C | Missense | 1 |
| Ovary | W81L | Missense | 1 |
| Pleura | P661Q | Missense | 1 |
| Skin | K629* | Nonsense | 1 |
| Skin | P904L | Missense | 1 |
| Skin | R510Q | Missense | 1 |
| Skin | T73I | Missense | 1 |
| Soft tissue | I173V | Missense | 1 |
| Stomach | K535R | Missense | 1 |
| Urinary tract | D818Y | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 10.3 | 25 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 20.7 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 0 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 31 | 50 |
| Liver | 27 | 0 | 3.4 | 0 |
| Lung | 174 | 0 | 6.9 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 3.4 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 3.4 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 10.3 | 25 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 3.4 | 0 |
| Stomach | 38 | 0 | 3.4 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 3.4 | 0 |