Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Bone | Y34C | Missense | 1 |
| Breast | D418N | Missense | 1 |
| Central nervous system | K843E | Missense | 1 |
| Central nervous system | Q521R | Missense | 1 |
| Central nervous system | R6Q | Missense | 1 |
| Central nervous system | V267I | Missense | 1 |
| Endometrium | E420A | Missense | 1 |
| Endometrium | E570* | Nonsense | 1 |
| Endometrium | K340T | Missense | 1 |
| Endometrium | P298S | Missense | 1 |
| Haematopoietic and lymphoid tissue | D359E | Missense | 1 |
| Haematopoietic and lymphoid tissue | I393N | Missense | 1 |
| Haematopoietic and lymphoid tissue | K467M | Missense | 1 |
| Haematopoietic and lymphoid tissue | R536* | Nonsense | 1 |
| Haematopoietic and lymphoid tissue | R82H | Missense | 1 |
| Large intestine | L441F | Missense | 1 |
| Large intestine | R82H | Missense | 1 |
| Liver | E457A | Missense | 1 |
| Lung | A208S | Missense | 1 |
| Lung | G703* | Nonsense | 1 |
| Lung | H292Y | Missense | 1 |
| Lung | L369P | Missense | 1 |
| Lung | N194I | Missense | 1 |
| Lung | P357H | Missense | 1 |
| Lung | P448H | Missense | 1 |
| Lung | P530L | Missense | 1 |
| Lung | R914S | Missense | 1 |
| Lung | S294L | Missense | 1 |
| Lung | S773* | Nonsense | 1 |
| Lung | V385F | Missense | 1 |
| Lung | V817L | Missense | 1 |
| Oesophagus | S411C | Missense | 1 |
| Ovary | G531R | Missense | 1 |
| Ovary | S685Y | Missense | 1 |
| Pancreas | K216E | Missense | 1 |
| Stomach | R6Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 3.1 | 0 |
| Breast | 58 | 0 | 3.1 | 0 |
| Central nervous system | 52 | 0 | 12.5 | 0 |
| Endometrium | 27 | 0 | 9.4 | 25 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 12.5 | 25 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 6.2 | 0 |
| Liver | 27 | 0 | 3.1 | 0 |
| Lung | 174 | 0 | 34.4 | 50 |
| Oesophagus | 25 | 0 | 3.1 | 0 |
| Ovary | 50 | 0 | 6.2 | 0 |
| Pancreas | 44 | 0 | 3.1 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 3.1 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |