Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | M1342T | Missense | 2 |
| Autonomic ganglia | P1232L | Missense | 1 |
| Autonomic ganglia | R344N | Missense | 1 |
| Central nervous system | S1137I | Missense | 1 |
| Endometrium | D382N | Missense | 1 |
| Endometrium | D453Y | Missense | 1 |
| Endometrium | E247* | Nonsense | 1 |
| Endometrium | E674* | Nonsense | 1 |
| Endometrium | L625F | Missense | 1 |
| Endometrium | S1415N | Missense | 1 |
| Endometrium | S567N | Missense | 1 |
| Haematopoietic and lymphoid tissue | D1537N | Missense | 1 |
| Haematopoietic and lymphoid tissue | F773L | Missense | 1 |
| Haematopoietic and lymphoid tissue | L1262L | Silent | 1 |
| Haematopoietic and lymphoid tissue | N1581S | Missense | 1 |
| Large intestine | A95V | Missense | 1 |
| Large intestine | G676D | Missense | 1 |
| Large intestine | I1032V | Missense | 1 |
| Large intestine | L1550S | Missense | 1 |
| Large intestine | P1519R | Missense | 1 |
| Large intestine | Q1061R | Missense | 1 |
| Large intestine | R1574I | Missense | 1 |
| Large intestine | R191T | Missense | 1 |
| Large intestine | R900Q | Missense | 1 |
| Large intestine | S126F | Missense | 1 |
| Large intestine | T943S | Missense | 1 |
| Liver | R1541M | Missense | 1 |
| Lung | A396S | Missense | 1 |
| Lung | C1176S | Missense | 1 |
| Lung | D1410N | Missense | 1 |
| Lung | D1680Y | Missense | 1 |
| Lung | E168G | Missense | 1 |
| Lung | E439K | Missense | 1 |
| Lung | E669G | Missense | 1 |
| Lung | R361T | Missense | 1 |
| Lung | S1683F | Missense | 1 |
| Lung | V258F | Missense | 1 |
| Oesophagus | L646V | Missense | 1 |
| Ovary | D1050N | Missense | 1 |
| Ovary | L1358V | Missense | 1 |
| Ovary | V1695A | Missense | 1 |
| Skin | R1708W | Missense | 1 |
| Soft tissue | I1471F | Missense | 1 |
| Stomach | L416R | Missense | 1 |
| Upper aerodigestive tract | K347R | Missense | 1 |
| Urinary tract | S1577C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 4.5 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 0 | 0 |
| Central nervous system | 52 | 0 | 2.3 | 0 |
| Endometrium | 27 | 0 | 11.4 | 100 |
| Haematopoietic and lymphoid tissue | 178 | 100 | 6.8 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 29.5 | 0 |
| Liver | 27 | 0 | 2.3 | 0 |
| Lung | 174 | 0 | 22.7 | 0 |
| Oesophagus | 25 | 0 | 2.3 | 0 |
| Ovary | 50 | 0 | 6.8 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 2.3 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 2.3 | 0 |
| Stomach | 38 | 0 | 2.3 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 2.3 | 0 |
| Urinary tract | 24 | 0 | 2.3 | 0 |