Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | V746M | Missense | 2 |
| Breast | R571Q | Missense | 1 |
| Endometrium | E674K | Missense | 1 |
| Endometrium | R398H | Missense | 1 |
| Endometrium | S297S | Silent | 1 |
| Endometrium | Y601H | Missense | 1 |
| Haematopoietic and lymphoid tissue | A585T | Missense | 1 |
| Haematopoietic and lymphoid tissue | G411R | Missense | 1 |
| Haematopoietic and lymphoid tissue | L842L | Silent | 1 |
| Haematopoietic and lymphoid tissue | R531C | Missense | 1 |
| Haematopoietic and lymphoid tissue | R576Q | Missense | 1 |
| Large intestine | D758N | Missense | 1 |
| Large intestine | D83G | Missense | 1 |
| Large intestine | E674K | Missense | 1 |
| Large intestine | L333S | Missense | 1 |
| Large intestine | Q827H | Missense | 1 |
| Large intestine | R398H | Missense | 1 |
| Large intestine | R461H | Missense | 1 |
| Large intestine | R538H | Missense | 1 |
| Large intestine | R545H | Missense | 1 |
| Large intestine | T401I | Missense | 1 |
| Large intestine | V616M | Missense | 1 |
| Lung | L282L | Silent | 1 |
| Lung | Q783H | Missense | 1 |
| Oesophagus | D817Y | Missense | 1 |
| Ovary | A585T | Missense | 1 |
| Ovary | C651Y | Missense | 1 |
| Pancreas | R149W | Missense | 1 |
| Pancreas | V746M | Missense | 1 |
| Soft tissue | D706N | Missense | 1 |
| Stomach | Y681Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 3.6 | 0 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 25 | 10.7 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 25 | 14.3 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 46.4 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 25 | 3.6 | 0 |
| Oesophagus | 25 | 0 | 3.6 | 0 |
| Ovary | 50 | 0 | 7.1 | 0 |
| Pancreas | 44 | 0 | 7.1 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 3.6 | 0 |
| Stomach | 38 | 25 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |