Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | E461K | Missense | 2 |
| Endometrium | I79V | Missense | 1 |
| Haematopoietic and lymphoid tissue | D210G | Missense | 1 |
| Haematopoietic and lymphoid tissue | R431H | Missense | 1 |
| Haematopoietic and lymphoid tissue | Y303H | Missense | 1 |
| Large intestine | A282T | Missense | 1 |
| Large intestine | D422N | Missense | 1 |
| Large intestine | E250K | Missense | 1 |
| Large intestine | K441N | Missense | 1 |
| Large intestine | S78P | Missense | 1 |
| Large intestine | Y67H | Missense | 1 |
| Liver | E203K | Missense | 1 |
| Skin | K476Q | Missense | 1 |
| Upper aerodigestive tract | G27G | Silent | 1 |
| Upper aerodigestive tract | P29P | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 0 | 0 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 7.1 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 21.4 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 57.1 | 0 |
| Liver | 27 | 0 | 7.1 | 0 |
| Lung | 174 | 0 | 0 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 7.1 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 100 | 0 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |