Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | S191P | Missense | 2 |
| Endometrium | P400H | Missense | 1 |
| Haematopoietic and lymphoid tissue | P23R | Missense | 1 |
| Kidney | K3E | Missense | 1 |
| Large intestine | D421Y | Missense | 1 |
| Large intestine | R301* | Nonsense | 1 |
| Lung | D391N | Missense | 1 |
| Lung | K121T | Missense | 1 |
| Lung | L384F | Missense | 1 |
| Lung | R345C | Missense | 1 |
| Oesophagus | V280I | Missense | 1 |
| Ovary | A110T | Missense | 1 |
| Upper aerodigestive tract | E397* | Nonsense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 0 | 0 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 8.3 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 8.3 | 0 |
| Kidney | 22 | 0 | 8.3 | 0 |
| Large intestine | 57 | 0 | 25 | 50 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 33.3 | 0 |
| Oesophagus | 25 | 0 | 8.3 | 0 |
| Ovary | 50 | 0 | 8.3 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 50 |
| Urinary tract | 24 | 0 | 0 | 0 |