Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Autonomic ganglia | A984T | Missense | 1 |
| Bone | A1011T | Missense | 1 |
| Breast | S512R | Missense | 1 |
| Breast | S758G | Missense | 1 |
| Central nervous system | S400L | Missense | 1 |
| Central nervous system | Y201C | Missense | 1 |
| Endometrium | A1011T | Missense | 1 |
| Endometrium | N763S | Missense | 1 |
| Endometrium | Q1006R | Missense | 1 |
| Endometrium | R448W | Missense | 1 |
| Haematopoietic and lymphoid tissue | D198N | Missense | 1 |
| Haematopoietic and lymphoid tissue | E1022K | Missense | 1 |
| Haematopoietic and lymphoid tissue | R132Q | Missense | 1 |
| Haematopoietic and lymphoid tissue | R138C | Missense | 1 |
| Large intestine | A167V | Missense | 1 |
| Large intestine | A373V | Missense | 1 |
| Large intestine | A706T | Missense | 1 |
| Large intestine | E717G | Missense | 1 |
| Large intestine | Q125E | Missense | 1 |
| Large intestine | R200H | Missense | 1 |
| Large intestine | R704H | Missense | 1 |
| Lung | A1013S | Missense | 1 |
| Lung | E519* | Nonsense | 1 |
| Lung | F888L | Missense | 1 |
| Lung | G220V | Missense | 1 |
| Lung | G897C | Missense | 1 |
| Lung | H766L | Missense | 1 |
| Lung | K737Q | Missense | 1 |
| Pancreas | S716L | Missense | 1 |
| Prostate | Q415* | Nonsense | 1 |
| Skin | D934N | Missense | 1 |
| Skin | L175* | Nonsense | 1 |
| Skin | P727L | Missense | 1 |
| Skin | P901S | Missense | 1 |
| Stomach | N726S | Missense | 1 |
| Stomach | R543L | Missense | 1 |
| Stomach | S716L | Missense | 1 |
| Urinary tract | A515V | Missense | 1 |
| Urinary tract | E538K | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 2.8 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 2.8 | 0 |
| Breast | 58 | 0 | 5.6 | 0 |
| Central nervous system | 52 | 0 | 5.6 | 0 |
| Endometrium | 27 | 0 | 11.1 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 11.1 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 19.4 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 16.7 | 33.3 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 2.8 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 33.3 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 8.3 | 33.3 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 8.3 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 0 | 0 |
| Urinary tract | 24 | 0 | 5.6 | 0 |