Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Breast | P1123V | Missense | 1 |
| Breast | V1151I | Missense | 1 |
| Central nervous system | P748T | Missense | 1 |
| Endometrium | A760T | Missense | 1 |
| Endometrium | H1170R | Missense | 1 |
| Endometrium | P308H | Missense | 1 |
| Endometrium | R870Q | Missense | 1 |
| Haematopoietic and lymphoid tissue | A234T | Missense | 1 |
| Haematopoietic and lymphoid tissue | E436D | Missense | 1 |
| Haematopoietic and lymphoid tissue | R134W | Missense | 1 |
| Haematopoietic and lymphoid tissue | S563T | Missense | 1 |
| Large intestine | A390T | Missense | 1 |
| Large intestine | A617T | Missense | 1 |
| Large intestine | L119P | Missense | 1 |
| Large intestine | T4I | Missense | 1 |
| Large intestine | V395I | Missense | 1 |
| Large intestine | W474* | Nonsense | 1 |
| Lung | A586S | Missense | 1 |
| Lung | G973R | Missense | 1 |
| Lung | R549P | Missense | 1 |
| Oesophagus | P45S | Missense | 1 |
| Oesophagus | S1068F | Missense | 1 |
| Ovary | A612T | Missense | 1 |
| Ovary | A770V | Missense | 1 |
| Ovary | A946G | Missense | 1 |
| Ovary | H113D | Missense | 1 |
| Skin | G696S | Missense | 1 |
| Stomach | Q72Q | Silent | 1 |
| Stomach | S220G | Missense | 1 |
| Stomach | Y1189C | Missense | 1 |
| Upper aerodigestive tract | R111R | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 7.1 | 0 |
| Central nervous system | 52 | 0 | 3.6 | 0 |
| Endometrium | 27 | 0 | 14.3 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 14.3 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 17.9 | 100 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 10.7 | 0 |
| Oesophagus | 25 | 0 | 7.1 | 0 |
| Ovary | 50 | 0 | 14.3 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 3.6 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 50 | 7.1 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 50 | 0 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |