Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Endometrium | V1228M | Missense | 2 |
| Breast | S96S | Silent | 1 |
| Central nervous system | P1214R | Missense | 1 |
| Endometrium | R999M | Missense | 1 |
| Endometrium | S1004G | Missense | 1 |
| Endometrium | S886L | Missense | 1 |
| Haematopoietic and lymphoid tissue | R1221C | Missense | 1 |
| Haematopoietic and lymphoid tissue | R233Q | Missense | 1 |
| Haematopoietic and lymphoid tissue | R27W | Missense | 1 |
| Haematopoietic and lymphoid tissue | V328I | Missense | 1 |
| Kidney | E102K | Missense | 1 |
| Large intestine | D156N | Missense | 1 |
| Large intestine | E187A | Missense | 1 |
| Large intestine | E191G | Missense | 1 |
| Large intestine | H888Y | Missense | 1 |
| Large intestine | L892I | Missense | 1 |
| Large intestine | P987L | Missense | 1 |
| Large intestine | Q180K | Missense | 1 |
| Large intestine | Q77H | Missense | 1 |
| Large intestine | R164* | Nonsense | 1 |
| Large intestine | R827* | Nonsense | 1 |
| Large intestine | S1038R | Missense | 1 |
| Large intestine | S1243* | Nonsense | 1 |
| Large intestine | T215P | Missense | 1 |
| Lung | H740Y | Missense | 1 |
| Ovary | R606Q | Missense | 1 |
| Pancreas | K240E | Missense | 1 |
| Prostate | A85A | Silent | 1 |
| Prostate | S90C | Missense | 1 |
| Prostate | V1001L | Missense | 1 |
| Skin | K38N | Missense | 1 |
| Stomach | G423W | Missense | 1 |
| Stomach | P936T | Missense | 1 |
| Upper aerodigestive tract | D156D | Silent | 1 |
| Upper aerodigestive tract | Q119Q | Silent | 1 |
| Urinary tract | R261P | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 25 | 0 | 0 |
| Central nervous system | 52 | 0 | 3.3 | 0 |
| Endometrium | 27 | 0 | 16.7 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 13.3 | 0 |
| Kidney | 22 | 0 | 3.3 | 0 |
| Large intestine | 57 | 0 | 33.3 | 100 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 3.3 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 3.3 | 0 |
| Pancreas | 44 | 0 | 3.3 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 25 | 6.7 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 3.3 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 6.7 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 50 | 0 | 0 |
| Urinary tract | 24 | 0 | 3.3 | 0 |