Frequency of SNVs in pancancer level

Cancer Type	Mutation	Mutation Type	# Sample
Autonomic ganglia	P2467R	Missense	2
Breast	Q2054E	Missense	2
Haematopoietic and lymphoid tissue	K3889Q	Missense	2
Large intestine	G3438D	Missense	2
Lung	P3082L	Missense	2
Lung	Q2176*	Nonsense	2
Urinary tract	A1691T	Missense	2
Bone	P4726S	Missense	1
Breast	C385Y	Missense	1
Breast	D553N	Missense	1
Breast	E1240*	Nonsense	1
Breast	E3716K	Missense	1
Breast	G892E	Missense	1
Breast	H4512N	Missense	1
Breast	L504P	Missense	1
Breast	Q3464L	Missense	1
Central nervous system	G892E	Missense	1
Central nervous system	I2391V	Missense	1
Central nervous system	P2051R	Missense	1
Central nervous system	R3398Q	Missense	1
Central nervous system	V3437L	Missense	1
Endometrium	D3457N	Missense	1
Endometrium	E300D	Missense	1
Endometrium	E4515*	Nonsense	1
Endometrium	E4531D	Missense	1
Endometrium	E665*	Nonsense	1
Endometrium	E937D	Missense	1
Endometrium	G908S	Missense	1
Endometrium	G917V	Missense	1
Endometrium	K1680T	Missense	1
Endometrium	K3604N	Missense	1
Endometrium	K3714R	Missense	1
Endometrium	K3889Q	Missense	1
Endometrium	L4206I	Missense	1
Endometrium	M1819I	Missense	1
Endometrium	N2980S	Missense	1
Endometrium	P4504L	Missense	1
Endometrium	R2139Q	Missense	1
Endometrium	R2610*	Nonsense	1
Endometrium	R3400H	Missense	1
Endometrium	R4725M	Missense	1
Endometrium	R4777Q	Missense	1
Endometrium	R973I	Missense	1
Endometrium	S4760L	Missense	1
Endometrium	S4872F	Missense	1
Endometrium	T4838M	Missense	1
Endometrium	V4463I	Missense	1
Endometrium	Y4657H	Missense	1
Haematopoietic and lymphoid tissue	C4855W	Missense	1
Haematopoietic and lymphoid tissue	E2626*	Nonsense	1
Haematopoietic and lymphoid tissue	E3384G	Missense	1
Haematopoietic and lymphoid tissue	F4170I	Missense	1
Haematopoietic and lymphoid tissue	G2568V	Missense	1
Haematopoietic and lymphoid tissue	L601V	Missense	1
Haematopoietic and lymphoid tissue	N1116Y	Missense	1
Haematopoietic and lymphoid tissue	P2012L	Missense	1
Haematopoietic and lymphoid tissue	P2493L	Missense	1
Haematopoietic and lymphoid tissue	P3082L	Missense	1
Haematopoietic and lymphoid tissue	Q3016H	Missense	1
Haematopoietic and lymphoid tissue	Q4140*	Nonsense	1
Haematopoietic and lymphoid tissue	R1058T	Missense	1
Haematopoietic and lymphoid tissue	R1229M	Missense	1
Haematopoietic and lymphoid tissue	R4595C	Missense	1
Haematopoietic and lymphoid tissue	S925F	Missense	1
Kidney	A3902G	Missense	1
Kidney	C3460F	Missense	1
Kidney	G2986D	Missense	1
Kidney	G892E	Missense	1
Large intestine	A1065T	Missense	1
Large intestine	C1013R	Missense	1
Large intestine	C139R	Missense	1
Large intestine	D4545G	Missense	1
Large intestine	E1313K	Missense	1
Large intestine	E3430L	Missense	1
Large intestine	E725K	Missense	1
Large intestine	F3385L	Missense	1
Large intestine	G1584R	Missense	1
Large intestine	G2579D	Missense	1
Large intestine	G2636C	Missense	1
Large intestine	G4457D	Missense	1
Large intestine	G4607V	Missense	1
Large intestine	I4868F	Missense	1
Large intestine	K3852E	Missense	1
Large intestine	K832E	Missense	1
Large intestine	M2522I	Missense	1
Large intestine	P2050L	Missense	1
Large intestine	P2415S	Missense	1
Large intestine	P2944L	Missense	1
Large intestine	P3082L	Missense	1
Large intestine	P4306L	Missense	1
Large intestine	P860S	Missense	1
Large intestine	Q3056E	Missense	1
Large intestine	Q384*	Nonsense	1
Large intestine	Q419R	Missense	1
Large intestine	R1137*	Nonsense	1
Large intestine	R2609*	Nonsense	1
Large intestine	R3252S	Missense	1
Large intestine	R3405*	Nonsense	1
Large intestine	R3853W	Missense	1
Large intestine	R3995*	Nonsense	1
Large intestine	R4544W	Missense	1
Large intestine	R526C	Missense	1
Large intestine	S1416L	Missense	1
Large intestine	S1630L	Missense	1
Large intestine	S3880Y	Missense	1
Large intestine	S3903F	Missense	1
Large intestine	T1465I	Missense	1
Large intestine	T1904A	Missense	1
Large intestine	T2605R	Missense	1
Large intestine	T693A	Missense	1
Large intestine	W449R	Missense	1
Large intestine	W491R	Missense	1
Liver	L3234F	Missense	1
Liver	Y4246C	Missense	1
Lung	A117V	Missense	1
Lung	A334V	Missense	1
Lung	A829D	Missense	1
Lung	D1128N	Missense	1
Lung	D1451Y	Missense	1
Lung	D3386Y	Missense	1
Lung	D597H	Missense	1
Lung	E1940V	Missense	1
Lung	E3406K	Missense	1
Lung	E3724K	Missense	1
Lung	F324L	Missense	1
Lung	G313*	Nonsense	1
Lung	G905A	Missense	1
Lung	G906C	Missense	1
Lung	I3092V	Missense	1
Lung	K4573E	Missense	1
Lung	L2922R	Missense	1
Lung	L354*	Nonsense	1
Lung	L4287F	Missense	1
Lung	P4033L	Missense	1
Lung	Q3016H	Missense	1
Lung	R3125W	Missense	1
Lung	R909M	Missense	1
Lung	S3394R	Missense	1
Lung	S848N	Missense	1
Lung	S888T	Missense	1
Lung	V2216F	Missense	1
Lung	V4115F	Missense	1
Lung	V4703F	Missense	1
Oesophagus	D1405Y	Missense	1
Oesophagus	D2843Y	Missense	1
Oesophagus	I3096V	Missense	1
Ovary	A221D	Missense	1
Ovary	A4192T	Missense	1
Ovary	C4432Y	Missense	1
Ovary	I823T	Missense	1
Ovary	L4126*	Nonsense	1
Ovary	L4575F	Missense	1
Ovary	R4529H	Missense	1
Ovary	R4690Q	Missense	1
Pancreas	G3770R	Missense	1
Pancreas	K170E	Missense	1
Pancreas	Q1072*	Nonsense	1
Pancreas	Q2997*	Nonsense	1
Pancreas	T831A	Missense	1
Prostate	A4065V	Missense	1
Prostate	H703Y	Missense	1
Prostate	L4142S	Missense	1
Prostate	M546T	Missense	1
Prostate	R4763Q	Missense	1
Prostate	S1790F	Missense	1
Prostate	T3156A	Missense	1
Salivary gland	Q1218*	Nonsense	1
Skin	E4319K	Missense	1
Skin	G4186C	Missense	1
Skin	G917R	Missense	1
Skin	I776K	Missense	1
Skin	I862L	Missense	1
Skin	K2009*	Nonsense	1
Skin	L3469F	Missense	1
Skin	N543D	Missense	1
Skin	P1669R	Missense	1
Skin	Q3792*	Nonsense	1
Soft tissue	R2307G	Missense	1
Soft tissue	R3217H	Missense	1
Stomach	F153V	Missense	1
Stomach	G915L	Missense	1
Stomach	P1838S	Missense	1
Thyroid	Q2177*	Nonsense	1
Thyroid	R1861Q	Missense	1
Upper aerodigestive tract	A4903A	Silent	1
Upper aerodigestive tract	E510Q	Missense	1
Upper aerodigestive tract	G4186D	Missense	1
Urinary tract	D1497H	Missense	1
Urinary tract	G1517R	Missense	1
Urinary tract	R1351M	Missense	1
Urinary tract	R2028*	Nonsense	1

Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines

Summary of mutation in pancancer level

Tissue Type	# Cell Line	% Silent	% Missense	% Nonsense
Autonomic ganglia	17	0	1.1	0
Biliary tract	7	0	0	0
Bone	25	0	0.6	0
Breast	58	0	5.2	4.3
Central nervous system	52	0	2.9	0
Endometrium	27	0	13.8	13
Haematopoietic and lymphoid tissue	178	0	9.2	8.7
Kidney	22	0	2.3	0
Large intestine	57	0	23.6	21.7
Liver	27	0	1.1	0
Lung	174	0	16.7	17.4
Oesophagus	25	0	1.7	0
Ovary	50	0	4	4.3
Pancreas	44	0	1.7	8.7
Pleura	10	0	0	0
Prostate	7	0	4	0
Salivary gland	2	0	0	4.3
Skin	60	0	4.6	8.7
Small intestine	1	0	0	0
Soft tissue	20	0	1.1	0
Stomach	38	0	1.7	0
Thyroid	12	0	0.6	4.3
Upper aerodigestive tract	30	100	1.1	0
Urinary tract	24	0	2.9	4.3