Cancer Type	Mutation	Mutation Type	# Sample
Large intestine	R2396Q	Missense	2
Autonomic ganglia	S1911R	Missense	1
Breast	E1980K	Missense	1
Breast	G114V	Missense	1
Breast	H2683R	Missense	1
Breast	S697*	Nonsense	1
Breast	V1993F	Missense	1
Central nervous system	E2341Q	Missense	1
Central nervous system	L664F	Missense	1
Central nervous system	V1993F	Missense	1
Endometrium	C1071*	Nonsense	1
Endometrium	D488N	Missense	1
Endometrium	E2240*	Nonsense	1
Endometrium	E707D	Missense	1
Endometrium	H724R	Missense	1
Endometrium	K791E	Missense	1
Endometrium	Q1967*	Nonsense	1
Endometrium	R1016*	Nonsense	1
Endometrium	R1786W	Missense	1
Endometrium	R2492W	Missense	1
Endometrium	R91*	Nonsense	1
Endometrium	R984H	Missense	1
Haematopoietic and lymphoid tissue	A1002E	Missense	1
Haematopoietic and lymphoid tissue	D37N	Missense	1
Haematopoietic and lymphoid tissue	G1555E	Missense	1
Haematopoietic and lymphoid tissue	K1978R	Missense	1
Haematopoietic and lymphoid tissue	K2397R	Missense	1
Haematopoietic and lymphoid tissue	Q901*	Nonsense	1
Haematopoietic and lymphoid tissue	R1492H	Missense	1
Haematopoietic and lymphoid tissue	R2497G	Missense	1
Haematopoietic and lymphoid tissue	S2932C	Missense	1
Haematopoietic and lymphoid tissue	V1993F	Missense	1
Kidney	V1993F	Missense	1
Large intestine	A2365D	Missense	1
Large intestine	A2478V	Missense	1
Large intestine	A625E	Missense	1
Large intestine	E1134D	Missense	1
Large intestine	E1639K	Missense	1
Large intestine	G1200D	Missense	1
Large intestine	G749E	Missense	1
Large intestine	L2573I	Missense	1
Large intestine	P1776S	Missense	1
Large intestine	Q303K	Missense	1
Large intestine	R1155*	Nonsense	1
Large intestine	R2435W	Missense	1
Large intestine	R702K	Missense	1
Large intestine	S276I	Missense	1
Large intestine	T1558I	Missense	1
Lung	A1934S	Missense	1
Lung	D116Y	Missense	1
Lung	D2317N	Missense	1
Lung	E1642K	Missense	1
Lung	E2035*	Nonsense	1
Lung	E548*	Nonsense	1
Lung	E658Q	Missense	1
Lung	G1928R	Missense	1
Lung	N2977T	Missense	1
Lung	Q1067*	Nonsense	1
Lung	Q1781L	Missense	1
Lung	Q927H	Missense	1
Lung	R1053*	Nonsense	1
Lung	R2861W	Missense	1
Lung	S276I	Missense	1
Lung	V1993F	Missense	1
Oesophagus	G810E	Missense	1
Oesophagus	L1762M	Missense	1
Oesophagus	P2181L	Missense	1
Ovary	D2682N	Missense	1
Ovary	Q303K	Missense	1
Pancreas	A1758G	Missense	1
Prostate	A1860V	Missense	1
Prostate	E2068*	Nonsense	1
Prostate	L1902M	Missense	1
Prostate	T2716M	Missense	1
Salivary gland	A597T	Missense	1
Skin	P2542L	Missense	1
Skin	P608Q	Missense	1
Skin	R2435W	Missense	1
Skin	S1751F	Missense	1
Skin	S2774L	Missense	1
Skin	T401A	Missense	1
Soft tissue	A341V	Missense	1
Soft tissue	I2482V	Missense	1
Soft tissue	Q2151H	Missense	1
Soft tissue	V1993F	Missense	1
Stomach	E2341Q	Missense	1
Stomach	K3020T	Missense	1
Stomach	R103H	Missense	1
Stomach	R896*	Nonsense	1
Thyroid	R866*	Nonsense	1
Thyroid	S1629C	Missense	1
Urinary tract	E2085D	Missense	1
Urinary tract	V1993F	Missense	1

Mutational percentage of Silent,  Missense and  Nonsense for various cancer cell lines

Tissue Type	# Cell Line	% Silent	% Missense	% Nonsense
Autonomic ganglia	17	0	1.3	0
Biliary tract	7	0	0	0
Bone	25	0	0	0
Breast	58	0	5.1	6.7
Central nervous system	52	0	3.8	0
Endometrium	27	0	8.9	33.3
Haematopoietic and lymphoid tissue	178	0	11.4	6.7
Kidney	22	0	1.3	0
Large intestine	57	0	20.3	6.7
Liver	27	0	0	0
Lung	174	0	15.2	26.7
Oesophagus	25	0	3.8	0
Ovary	50	0	2.5	0
Pancreas	44	0	1.3	0
Pleura	10	0	0	0
Prostate	7	0	3.8	6.7
Salivary gland	2	0	1.3	0
Skin	60	0	7.6	0
Small intestine	1	0	0	0
Soft tissue	20	0	5.1	0
Stomach	38	0	3.8	6.7
Thyroid	12	0	1.3	6.7
Upper aerodigestive tract	30	0	0	0
Urinary tract	24	0	2.5	0