Cancer Type	Mutation	Mutation Type	# Sample
Endometrium	S1824L	Missense	2
Large intestine	A1220V	Missense	2
Liver	V2425M	Missense	2
Urinary tract	Q2311L	Missense	2
Autonomic ganglia	R868Q	Missense	1
Bone	L227W	Missense	1
Bone	R765K	Missense	1
Breast	A1308V	Missense	1
Breast	E1515*	Nonsense	1
Breast	K925N	Missense	1
Central nervous system	K1467E	Missense	1
Central nervous system	V1890L	Missense	1
Endometrium	A2712T	Missense	1
Endometrium	A2798D	Missense	1
Endometrium	D1623Y	Missense	1
Endometrium	D2693G	Missense	1
Endometrium	E1185*	Nonsense	1
Endometrium	H2060Y	Missense	1
Endometrium	K2622R	Missense	1
Endometrium	L1913P	Missense	1
Endometrium	M264L	Missense	1
Endometrium	N955K	Missense	1
Endometrium	Q971P	Missense	1
Endometrium	R1449M	Missense	1
Endometrium	R1837*	Nonsense	1
Endometrium	R2112I	Missense	1
Endometrium	R808*	Nonsense	1
Endometrium	R841*	Nonsense	1
Endometrium	S2412P	Missense	1
Endometrium	S368P	Missense	1
Endometrium	V1748A	Missense	1
Endometrium	V2003G	Missense	1
Endometrium	V928L	Missense	1
Haematopoietic and lymphoid tissue	G1614E	Missense	1
Haematopoietic and lymphoid tissue	M1156V	Missense	1
Haematopoietic and lymphoid tissue	M1793I	Missense	1
Haematopoietic and lymphoid tissue	R2721*	Nonsense	1
Haematopoietic and lymphoid tissue	S1672F	Missense	1
Haematopoietic and lymphoid tissue	S484P	Missense	1
Haematopoietic and lymphoid tissue	S63L	Missense	1
Kidney	D1298N	Missense	1
Large intestine	A1308V	Missense	1
Large intestine	A2537V	Missense	1
Large intestine	A2698V	Missense	1
Large intestine	D2676N	Missense	1
Large intestine	D2720G	Missense	1
Large intestine	E2487G	Missense	1
Large intestine	E2528*	Nonsense	1
Large intestine	E2703G	Missense	1
Large intestine	E337*	Nonsense	1
Large intestine	G1644R	Missense	1
Large intestine	G2585R	Missense	1
Large intestine	H198R	Missense	1
Large intestine	H249N	Missense	1
Large intestine	K1674R	Missense	1
Large intestine	L1016R	Missense	1
Large intestine	M1063T	Missense	1
Large intestine	R1894H	Missense	1
Large intestine	R321I	Missense	1
Large intestine	R868*	Nonsense	1
Large intestine	S2652P	Missense	1
Large intestine	T2328A	Missense	1
Large intestine	V2003I	Missense	1
Large intestine	Y1328H	Missense	1
Liver	S2692*	Nonsense	1
Lung	D1112N	Missense	1
Lung	D2155H	Missense	1
Lung	E1157Q	Missense	1
Lung	E2386Q	Missense	1
Lung	G884W	Missense	1
Lung	H1920Q	Missense	1
Lung	H870Q	Missense	1
Lung	L13R	Missense	1
Lung	L2057P	Missense	1
Lung	N574S	Missense	1
Lung	R808Q	Missense	1
Lung	R894H	Missense	1
Lung	S1280F	Missense	1
Lung	S349C	Missense	1
Lung	S616R	Missense	1
Lung	V1670G	Missense	1
Oesophagus	M540I	Missense	1
Oesophagus	P2378L	Missense	1
Oesophagus	T2695T	Silent	1
Ovary	R1636C	Missense	1
Pancreas	K1180*	Nonsense	1
Pancreas	S2389I	Missense	1
Prostate	D1022G	Missense	1
Prostate	V2707F	Missense	1
Skin	A342E	Missense	1
Skin	K1034E	Missense	1
Skin	L1840F	Missense	1
Skin	P1228S	Missense	1
Skin	Q1045H	Missense	1
Skin	T2731S	Missense	1
Soft tissue	D1874A	Missense	1
Stomach	D562N	Missense	1
Stomach	F2103V	Missense	1
Stomach	K927E	Missense	1
Stomach	P567S	Missense	1
Stomach	R1819L	Missense	1
Stomach	S1134F	Missense	1
Stomach	T2695M	Missense	1
Stomach	T528M	Missense	1
Upper aerodigestive tract	D2720D	Silent	1
Upper aerodigestive tract	K565E	Missense	1
Upper aerodigestive tract	Q2723Q	Silent	1
Urinary tract	N968S	Missense	1
Urinary tract	R816H	Missense	1
Urinary tract	Y178*	Nonsense	1

Mutational percentage of Silent,  Missense and  Nonsense for various cancer cell lines

Tissue Type	# Cell Line	% Silent	% Missense	% Nonsense
Autonomic ganglia	17	0	1	0
Biliary tract	7	0	0	0
Bone	25	0	2	0
Breast	58	0	2	8.3
Central nervous system	52	0	2	0
Endometrium	27	0	19.2	33.3
Haematopoietic and lymphoid tissue	178	0	6.1	8.3
Kidney	22	0	1	0
Large intestine	57	0	22.2	25
Liver	27	0	2	8.3
Lung	174	0	16.2	0
Oesophagus	25	33.3	2	0
Ovary	50	0	1	0
Pancreas	44	0	1	8.3
Pleura	10	0	0	0
Prostate	7	0	2	0
Salivary gland	2	0	0	0
Skin	60	0	6.1	0
Small intestine	1	0	0	0
Soft tissue	20	0	1	0
Stomach	38	0	8.1	0
Thyroid	12	0	0	0
Upper aerodigestive tract	30	66.7	1	0
Urinary tract	24	0	4	8.3