Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | V2618I | Missense | 2 |
| Biliary tract | V2618I | Missense | 1 |
| Bone | A1066V | Missense | 1 |
| Bone | H1096Y | Missense | 1 |
| Breast | G2496D | Missense | 1 |
| Breast | I852L | Missense | 1 |
| Breast | L2063V | Missense | 1 |
| Breast | R2199C | Missense | 1 |
| Breast | S1654C | Missense | 1 |
| Central nervous system | L1127R | Missense | 1 |
| Endometrium | A2268V | Missense | 1 |
| Endometrium | A2536V | Missense | 1 |
| Endometrium | C193Y | Missense | 1 |
| Endometrium | E1499D | Missense | 1 |
| Endometrium | G1973D | Missense | 1 |
| Endometrium | L253I | Missense | 1 |
| Endometrium | P530L | Missense | 1 |
| Endometrium | Q2579E | Missense | 1 |
| Endometrium | R1952W | Missense | 1 |
| Endometrium | R2039H | Missense | 1 |
| Endometrium | S1724C | Missense | 1 |
| Endometrium | T145I | Missense | 1 |
| Haematopoietic and lymphoid tissue | E1617* | Nonsense | 1 |
| Haematopoietic and lymphoid tissue | H1096Y | Missense | 1 |
| Haematopoietic and lymphoid tissue | K204R | Missense | 1 |
| Haematopoietic and lymphoid tissue | P2011L | Missense | 1 |
| Haematopoietic and lymphoid tissue | P2075Q | Missense | 1 |
| Haematopoietic and lymphoid tissue | R1188S | Missense | 1 |
| Haematopoietic and lymphoid tissue | R2187P | Missense | 1 |
| Haematopoietic and lymphoid tissue | T672I | Missense | 1 |
| Haematopoietic and lymphoid tissue | V2345F | Missense | 1 |
| Kidney | T4N | Missense | 1 |
| Large intestine | A2427V | Missense | 1 |
| Large intestine | C1897W | Missense | 1 |
| Large intestine | C810R | Missense | 1 |
| Large intestine | D1672Y | Missense | 1 |
| Large intestine | G951* | Nonsense | 1 |
| Large intestine | K2377T | Missense | 1 |
| Large intestine | N1020D | Missense | 1 |
| Large intestine | P2227S | Missense | 1 |
| Large intestine | Q1474P | Missense | 1 |
| Large intestine | R1200W | Missense | 1 |
| Large intestine | T1592A | Missense | 1 |
| Large intestine | T2446N | Missense | 1 |
| Large intestine | W2625C | Missense | 1 |
| Lung | A1066S | Missense | 1 |
| Lung | A2144S | Missense | 1 |
| Lung | D1004Y | Missense | 1 |
| Lung | D1111Y | Missense | 1 |
| Lung | K1898* | Nonsense | 1 |
| Lung | N1443S | Missense | 1 |
| Lung | Q1940K | Missense | 1 |
| Lung | R1233W | Missense | 1 |
| Lung | R632Q | Missense | 1 |
| Lung | R941C | Missense | 1 |
| Lung | S2181C | Missense | 1 |
| Oesophagus | D2197N | Missense | 1 |
| Ovary | R1031* | Nonsense | 1 |
| Ovary | T1063A | Missense | 1 |
| Ovary | T1396M | Missense | 1 |
| Pancreas | Q2579E | Missense | 1 |
| Pancreas | V2618I | Missense | 1 |
| Soft tissue | C2508Y | Missense | 1 |
| Soft tissue | R1188S | Missense | 1 |
| Stomach | N1746K | Missense | 1 |
| Upper aerodigestive tract | G1656C | Missense | 1 |
| Upper aerodigestive tract | V2618I | Missense | 1 |
| Urinary tract | S1890P | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 1.5 | 0 |
| Bone | 25 | 0 | 3.1 | 0 |
| Breast | 58 | 0 | 7.7 | 0 |
| Central nervous system | 52 | 0 | 1.5 | 0 |
| Endometrium | 27 | 0 | 18.5 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 12.3 | 25 |
| Kidney | 22 | 0 | 1.5 | 0 |
| Large intestine | 57 | 0 | 21.5 | 25 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 15.4 | 25 |
| Oesophagus | 25 | 0 | 1.5 | 0 |
| Ovary | 50 | 0 | 3.1 | 25 |
| Pancreas | 44 | 0 | 3.1 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 3.1 | 0 |
| Stomach | 38 | 0 | 1.5 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 3.1 | 0 |
| Urinary tract | 24 | 0 | 1.5 | 0 |