Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Biliary tract | L147L | Silent | 1 |
| Breast | D739Y | Missense | 1 |
| Breast | T177I | Missense | 1 |
| Central nervous system | P393R | Missense | 1 |
| Endometrium | E662D | Missense | 1 |
| Endometrium | L489S | Missense | 1 |
| Endometrium | R199Q | Missense | 1 |
| Endometrium | R516Q | Missense | 1 |
| Endometrium | S673G | Missense | 1 |
| Haematopoietic and lymphoid tissue | G480E | Missense | 1 |
| Haematopoietic and lymphoid tissue | P625L | Missense | 1 |
| Haematopoietic and lymphoid tissue | R649H | Missense | 1 |
| Haematopoietic and lymphoid tissue | Y650C | Missense | 1 |
| Large intestine | A712T | Missense | 1 |
| Large intestine | D379N | Missense | 1 |
| Large intestine | E725G | Missense | 1 |
| Large intestine | K238T | Missense | 1 |
| Large intestine | M407T | Missense | 1 |
| Large intestine | V383I | Missense | 1 |
| Lung | G495D | Missense | 1 |
| Lung | Q632H | Missense | 1 |
| Salivary gland | E432K | Missense | 1 |
| Upper aerodigestive tract | I270K | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 100 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 9.1 | 0 |
| Central nervous system | 52 | 0 | 4.5 | 0 |
| Endometrium | 27 | 0 | 22.7 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 18.2 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 27.3 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 9.1 | 0 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 4.5 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 4.5 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |