Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Autonomic ganglia | E101* | Nonsense | 1 |
| Breast | G528S | Missense | 1 |
| Breast | R576K | Missense | 1 |
| Breast | W507C | Missense | 1 |
| Central nervous system | M687I | Missense | 1 |
| Endometrium | A444V | Missense | 1 |
| Haematopoietic and lymphoid tissue | G506A | Missense | 1 |
| Haematopoietic and lymphoid tissue | G840S | Missense | 1 |
| Haematopoietic and lymphoid tissue | V148L | Missense | 1 |
| Kidney | E426A | Missense | 1 |
| Large intestine | G648R | Missense | 1 |
| Large intestine | V91M | Missense | 1 |
| Lung | C456* | Nonsense | 1 |
| Lung | D482Y | Missense | 1 |
| Lung | G208R | Missense | 1 |
| Lung | P495S | Missense | 1 |
| Lung | P62S | Missense | 1 |
| Lung | S467N | Missense | 1 |
| Lung | W622L | Missense | 1 |
| Ovary | L418V | Missense | 1 |
| Pancreas | R401C | Missense | 1 |
| Skin | G599E | Missense | 1 |
| Thyroid | C188R | Missense | 1 |
| Upper aerodigestive tract | S518N | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 50 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 13.6 | 0 |
| Central nervous system | 52 | 0 | 4.5 | 0 |
| Endometrium | 27 | 0 | 4.5 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 13.6 | 0 |
| Kidney | 22 | 0 | 4.5 | 0 |
| Large intestine | 57 | 0 | 9.1 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 27.3 | 50 |
| Oesophagus | 25 | 0 | 0 | 0 |
| Ovary | 50 | 0 | 4.5 | 0 |
| Pancreas | 44 | 0 | 4.5 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 4.5 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 4.5 | 0 |
| Upper aerodigestive tract | 30 | 0 | 4.5 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |