Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Stomach | T218A | Missense | 2 |
| Autonomic ganglia | R467G | Missense | 1 |
| Breast | T404S | Missense | 1 |
| Endometrium | A774T | Missense | 1 |
| Endometrium | E328* | Nonsense | 1 |
| Endometrium | E515* | Nonsense | 1 |
| Endometrium | I682M | Missense | 1 |
| Endometrium | R747H | Missense | 1 |
| Endometrium | S39N | Missense | 1 |
| Endometrium | V295I | Missense | 1 |
| Haematopoietic and lymphoid tissue | D389A | Missense | 1 |
| Haematopoietic and lymphoid tissue | K993* | Nonsense | 1 |
| Haematopoietic and lymphoid tissue | S477C | Missense | 1 |
| Haematopoietic and lymphoid tissue | V45A | Missense | 1 |
| Kidney | K607* | Nonsense | 1 |
| Kidney | T218A | Missense | 1 |
| Large intestine | D549N | Missense | 1 |
| Large intestine | P704S | Missense | 1 |
| Large intestine | Q484H | Missense | 1 |
| Large intestine | R124* | Nonsense | 1 |
| Large intestine | Y194D | Missense | 1 |
| Liver | S582* | Nonsense | 1 |
| Lung | E433* | Nonsense | 1 |
| Lung | G908R | Missense | 1 |
| Lung | H684Y | Missense | 1 |
| Lung | P803A | Missense | 1 |
| Lung | Q23* | Nonsense | 1 |
| Lung | S196R | Missense | 1 |
| Oesophagus | K668Q | Missense | 1 |
| Prostate | C563S | Missense | 1 |
| Skin | F795L | Missense | 1 |
| Skin | G87K | Missense | 1 |
| Skin | P708L | Missense | 1 |
| Skin | Q821* | Nonsense | 1 |
| Skin | R728Q | Missense | 1 |
| Stomach | D318V | Missense | 1 |
| Stomach | Y499C | Missense | 1 |
| Upper aerodigestive tract | E734K | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 3.3 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 3.3 | 0 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 16.7 | 22.2 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 10 | 11.1 |
| Kidney | 22 | 0 | 3.3 | 11.1 |
| Large intestine | 57 | 0 | 13.3 | 11.1 |
| Liver | 27 | 0 | 0 | 11.1 |
| Lung | 174 | 0 | 13.3 | 22.2 |
| Oesophagus | 25 | 0 | 3.3 | 0 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 3.3 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 13.3 | 11.1 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 13.3 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 3.3 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |