Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | S568G | Missense | 2 |
| Breast | E723K | Missense | 1 |
| Endometrium | L529I | Missense | 1 |
| Endometrium | P573S | Missense | 1 |
| Haematopoietic and lymphoid tissue | P391S | Missense | 1 |
| Large intestine | G340V | Missense | 1 |
| Large intestine | G518R | Missense | 1 |
| Large intestine | R360C | Missense | 1 |
| Large intestine | R508C | Missense | 1 |
| Large intestine | T354A | Missense | 1 |
| Liver | C457G | Missense | 1 |
| Lung | E610V | Missense | 1 |
| Lung | P224R | Missense | 1 |
| Lung | R439M | Missense | 1 |
| Lung | T438S | Missense | 1 |
| Lung | V613L | Missense | 1 |
| Lung | Y434C | Missense | 1 |
| Lung | Y643C | Missense | 1 |
| Oesophagus | E584* | Nonsense | 1 |
| Stomach | P171Q | Missense | 1 |
| Upper aerodigestive tract | D629V | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 4.8 | 0 |
| Central nervous system | 52 | 0 | 0 | 0 |
| Endometrium | 27 | 0 | 9.5 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 4.8 | 0 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 33.3 | 0 |
| Liver | 27 | 0 | 4.8 | 0 |
| Lung | 174 | 0 | 33.3 | 0 |
| Oesophagus | 25 | 0 | 0 | 100 |
| Ovary | 50 | 0 | 0 | 0 |
| Pancreas | 44 | 0 | 0 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 0 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 4.8 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 4.8 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |