Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Autonomic ganglia | R1245Q | Missense | 1 |
| Autonomic ganglia | S1740Y | Missense | 1 |
| Breast | A1024T | Missense | 1 |
| Breast | C326R | Missense | 1 |
| Breast | E703Q | Missense | 1 |
| Breast | L867R | Missense | 1 |
| Breast | S1042C | Missense | 1 |
| Central nervous system | P215L | Missense | 1 |
| Endometrium | A31T | Missense | 1 |
| Endometrium | C1087F | Missense | 1 |
| Endometrium | E1078A | Missense | 1 |
| Endometrium | E1126A | Missense | 1 |
| Endometrium | E222A | Missense | 1 |
| Endometrium | E706K | Missense | 1 |
| Endometrium | G32R | Missense | 1 |
| Endometrium | G680V | Missense | 1 |
| Endometrium | I1578I | Silent | 1 |
| Endometrium | K168N | Missense | 1 |
| Endometrium | Q1320H | Missense | 1 |
| Endometrium | Q611R | Missense | 1 |
| Endometrium | Q829R | Missense | 1 |
| Endometrium | R1043H | Missense | 1 |
| Endometrium | R864Q | Missense | 1 |
| Endometrium | T1479T | Silent | 1 |
| Haematopoietic and lymphoid tissue | A1354A | Silent | 1 |
| Haematopoietic and lymphoid tissue | C870Y | Missense | 1 |
| Haematopoietic and lymphoid tissue | G68D | Missense | 1 |
| Haematopoietic and lymphoid tissue | Q1538E | Missense | 1 |
| Haematopoietic and lymphoid tissue | R638H | Missense | 1 |
| Haematopoietic and lymphoid tissue | Y986D | Missense | 1 |
| Kidney | E1120A | Missense | 1 |
| Large intestine | A1527V | Missense | 1 |
| Large intestine | C1288R | Missense | 1 |
| Large intestine | C1498C | Silent | 1 |
| Large intestine | E1735A | Missense | 1 |
| Large intestine | G164E | Missense | 1 |
| Large intestine | K1030N | Missense | 1 |
| Large intestine | N1594D | Missense | 1 |
| Large intestine | R1217H | Missense | 1 |
| Large intestine | R949H | Missense | 1 |
| Liver | D1521Y | Missense | 1 |
| Lung | D1170G | Missense | 1 |
| Lung | E1244K | Missense | 1 |
| Lung | E502D | Missense | 1 |
| Lung | G446V | Missense | 1 |
| Lung | R1018H | Missense | 1 |
| Lung | R1228Q | Missense | 1 |
| Oesophagus | R1043H | Missense | 1 |
| Ovary | A1527A | Silent | 1 |
| Ovary | D1669V | Missense | 1 |
| Ovary | M1121T | Missense | 1 |
| Pancreas | R1029H | Missense | 1 |
| Pancreas | S343F | Missense | 1 |
| Salivary gland | I1409V | Missense | 1 |
| Skin | A83T | Missense | 1 |
| Skin | S1676F | Missense | 1 |
| Skin | S650F | Missense | 1 |
| Stomach | A466V | Missense | 1 |
| Stomach | I1344T | Missense | 1 |
| Stomach | R1511H | Missense | 1 |
| Upper aerodigestive tract | D330N | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 3.6 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 8.9 | 0 |
| Central nervous system | 52 | 0 | 1.8 | 0 |
| Endometrium | 27 | 40 | 25 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 20 | 8.9 | 0 |
| Kidney | 22 | 0 | 1.8 | 0 |
| Large intestine | 57 | 20 | 14.3 | 0 |
| Liver | 27 | 0 | 1.8 | 0 |
| Lung | 174 | 0 | 10.7 | 0 |
| Oesophagus | 25 | 0 | 1.8 | 0 |
| Ovary | 50 | 20 | 3.6 | 0 |
| Pancreas | 44 | 0 | 3.6 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 1.8 | 0 |
| Skin | 60 | 0 | 5.4 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 0 | 0 |
| Stomach | 38 | 0 | 5.4 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 1.8 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |