Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Lung | L328R | Missense | 2 |
| Autonomic ganglia | R144H | Missense | 1 |
| Central nervous system | A728D | Missense | 1 |
| Endometrium | K132R | Missense | 1 |
| Endometrium | S412F | Missense | 1 |
| Endometrium | S80G | Missense | 1 |
| Haematopoietic and lymphoid tissue | C1156Y | Missense | 1 |
| Haematopoietic and lymphoid tissue | E817K | Missense | 1 |
| Haematopoietic and lymphoid tissue | E829K | Missense | 1 |
| Haematopoietic and lymphoid tissue | S846* | Nonsense | 1 |
| Haematopoietic and lymphoid tissue | S911L | Missense | 1 |
| Large intestine | A298T | Missense | 1 |
| Large intestine | M716V | Missense | 1 |
| Large intestine | R117H | Missense | 1 |
| Large intestine | S387I | Missense | 1 |
| Liver | P677R | Missense | 1 |
| Liver | Q620R | Missense | 1 |
| Lung | G450R | Missense | 1 |
| Lung | S289* | Nonsense | 1 |
| Oesophagus | G450R | Missense | 1 |
| Oesophagus | Q620R | Missense | 1 |
| Ovary | A478S | Missense | 1 |
| Pancreas | T800S | Missense | 1 |
| Skin | P37L | Missense | 1 |
| Skin | S498F | Missense | 1 |
| Soft tissue | V407L | Missense | 1 |
| Upper aerodigestive tract | R835C | Missense | 1 |
| Urinary tract | L720F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 3.7 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 0 | 0 |
| Central nervous system | 52 | 0 | 3.7 | 0 |
| Endometrium | 27 | 0 | 11.1 | 0 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 14.8 | 50 |
| Kidney | 22 | 0 | 0 | 0 |
| Large intestine | 57 | 0 | 14.8 | 0 |
| Liver | 27 | 0 | 7.4 | 0 |
| Lung | 174 | 0 | 11.1 | 50 |
| Oesophagus | 25 | 0 | 7.4 | 0 |
| Ovary | 50 | 0 | 3.7 | 0 |
| Pancreas | 44 | 0 | 3.7 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 0 | 0 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 7.4 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 3.7 | 0 |
| Stomach | 38 | 0 | 0 | 0 |
| Thyroid | 12 | 0 | 0 | 0 |
| Upper aerodigestive tract | 30 | 0 | 3.7 | 0 |
| Urinary tract | 24 | 0 | 3.7 | 0 |