Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer Type | Mutation | Mutation Type | # Sample |
|---|---|---|---|
| Large intestine | H44Y | Missense | 2 |
| Breast | E1000Q | Missense | 1 |
| Breast | M653V | Missense | 1 |
| Breast | T387S | Missense | 1 |
| Central nervous system | E668Q | Missense | 1 |
| Central nervous system | S227F | Missense | 1 |
| Endometrium | A273T | Missense | 1 |
| Endometrium | D1748G | Missense | 1 |
| Endometrium | E1782G | Missense | 1 |
| Endometrium | E661* | Nonsense | 1 |
| Endometrium | E682D | Missense | 1 |
| Endometrium | G1302C | Missense | 1 |
| Endometrium | K813N | Missense | 1 |
| Endometrium | L708F | Missense | 1 |
| Endometrium | M721V | Missense | 1 |
| Endometrium | N1730S | Missense | 1 |
| Endometrium | T1275I | Missense | 1 |
| Endometrium | V764A | Missense | 1 |
| Haematopoietic and lymphoid tissue | C1183S | Missense | 1 |
| Haematopoietic and lymphoid tissue | C1380fs | Missense | 1 |
| Haematopoietic and lymphoid tissue | E33A | Missense | 1 |
| Haematopoietic and lymphoid tissue | G42C | Missense | 1 |
| Haematopoietic and lymphoid tissue | I550F | Missense | 1 |
| Haematopoietic and lymphoid tissue | R1687* | Nonsense | 1 |
| Haematopoietic and lymphoid tissue | S335C | Missense | 1 |
| Haematopoietic and lymphoid tissue | T159I | Missense | 1 |
| Haematopoietic and lymphoid tissue | V1492L | Missense | 1 |
| Kidney | A169P | Missense | 1 |
| Large intestine | A1939V | Missense | 1 |
| Large intestine | F312L | Missense | 1 |
| Large intestine | L522H | Missense | 1 |
| Large intestine | M485I | Missense | 1 |
| Large intestine | T1001A | Missense | 1 |
| Large intestine | V1251A | Missense | 1 |
| Large intestine | V1262A | Missense | 1 |
| Lung | D552G | Missense | 1 |
| Lung | E662* | Nonsense | 1 |
| Lung | G666V | Missense | 1 |
| Lung | K1499T | Missense | 1 |
| Lung | S1576N | Missense | 1 |
| Oesophagus | R1818Q | Missense | 1 |
| Ovary | S1373R | Missense | 1 |
| Ovary | T22S | Missense | 1 |
| Pancreas | T1927M | Missense | 1 |
| Prostate | G1516R | Missense | 1 |
| Prostate | Q111* | Nonsense | 1 |
| Prostate | R639Q | Missense | 1 |
| Skin | P1071T | Missense | 1 |
| Skin | R1663C | Missense | 1 |
| Soft tissue | S227F | Missense | 1 |
| Stomach | A1933S | Missense | 1 |
| Stomach | A437T | Missense | 1 |
| Stomach | P555A | Missense | 1 |
| Stomach | R1583T | Missense | 1 |
| Stomach | S335C | Missense | 1 |
| Thyroid | D1353N | Missense | 1 |
| Upper aerodigestive tract | R1243C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancer cell lines
Summary of mutation in pancancer level
| Tissue Type | # Cell Line | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|
| Autonomic ganglia | 17 | 0 | 0 | 0 |
| Biliary tract | 7 | 0 | 0 | 0 |
| Bone | 25 | 0 | 0 | 0 |
| Breast | 58 | 0 | 5.6 | 0 |
| Central nervous system | 52 | 0 | 3.7 | 0 |
| Endometrium | 27 | 0 | 20.4 | 25 |
| Haematopoietic and lymphoid tissue | 178 | 0 | 14.8 | 25 |
| Kidney | 22 | 0 | 1.9 | 0 |
| Large intestine | 57 | 0 | 16.7 | 0 |
| Liver | 27 | 0 | 0 | 0 |
| Lung | 174 | 0 | 7.4 | 25 |
| Oesophagus | 25 | 0 | 1.9 | 0 |
| Ovary | 50 | 0 | 3.7 | 0 |
| Pancreas | 44 | 0 | 1.9 | 0 |
| Pleura | 10 | 0 | 0 | 0 |
| Prostate | 7 | 0 | 3.7 | 25 |
| Salivary gland | 2 | 0 | 0 | 0 |
| Skin | 60 | 0 | 3.7 | 0 |
| Small intestine | 1 | 0 | 0 | 0 |
| Soft tissue | 20 | 0 | 1.9 | 0 |
| Stomach | 38 | 0 | 9.3 | 0 |
| Thyroid | 12 | 0 | 1.9 | 0 |
| Upper aerodigestive tract | 30 | 0 | 1.9 | 0 |
| Urinary tract | 24 | 0 | 0 | 0 |