Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D17H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E124Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E241D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E94K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K379T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L168L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P373S | Missense | 1 |
| BRCA | Breast invasive carcinoma | D261N | Missense | 1 |
| BRCA | Breast invasive carcinoma | V111V | Silent | 1 |
| CESC | Cervical and endocervical cancers | F210L | Missense | 1 |
| CESC | Cervical and endocervical cancers | I41V | Missense | 1 |
| CESC | Cervical and endocervical cancers | L209L | Silent | 1 |
| COAD | Colon adenocarcinoma | E134D | Missense | 1 |
| COAD | Colon adenocarcinoma | H105H | Silent | 1 |
| COAD | Colon adenocarcinoma | H251Y | Missense | 1 |
| COAD | Colon adenocarcinoma | K135Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R389L | Missense | 1 |
| COAD | Colon adenocarcinoma | W250* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | K421K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D104N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G50R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R239I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S318* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R377Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S402P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T175A | Missense | 1 |
| LUAD | Lung adenocarcinoma | D95E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E142Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E80K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G58G | Silent | 1 |
| LUAD | Lung adenocarcinoma | I202I | Silent | 1 |
| LUAD | Lung adenocarcinoma | P283R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P38T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T22A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R133I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V350M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V44V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P66S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D97N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G26D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R76H | Missense | 1 |
| READ | Rectum adenocarcinoma | E417* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R377W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F150F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S20F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V11V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V258I | Missense | 1 |
| STAD | Stomach adenocarcinoma | H251R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q422P | Missense | 1 |
| STAD | Stomach adenocarcinoma | R301W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S326R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A174V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G163G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N384I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R164C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R239I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R363G | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.1 | 14 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 9.1 | 2.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 9.1 | 4.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.1 | 9.3 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 9.1 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 7 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 18.2 | 14 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 9.1 | 4.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.3 | 33.3 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 18.2 | 4.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 9.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 11.6 | 0 |