Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E314K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F456F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I347L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S179S | Silent | 1 |
| BRCA | Breast invasive carcinoma | F6F | Silent | 1 |
| BRCA | Breast invasive carcinoma | I252I | Silent | 1 |
| BRCA | Breast invasive carcinoma | I577I | Silent | 1 |
| BRCA | Breast invasive carcinoma | R304Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y156C | Missense | 1 |
| CESC | Cervical and endocervical cancers | G164E | Missense | 1 |
| CESC | Cervical and endocervical cancers | V24M | Missense | 1 |
| COAD | Colon adenocarcinoma | A378A | Silent | 1 |
| COAD | Colon adenocarcinoma | A583T | Missense | 1 |
| COAD | Colon adenocarcinoma | D129N | Missense | 1 |
| COAD | Colon adenocarcinoma | K177N | Missense | 1 |
| COAD | Colon adenocarcinoma | K481N | Missense | 1 |
| COAD | Colon adenocarcinoma | T193T | Silent | 1 |
| ESCA | Esophageal carcinoma | E322Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R224C | Missense | 1 |
| GBM | Glioblastoma multiforme | R312W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L213V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P131S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R518R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S519F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y557F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L487M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M409R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N309S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D267D | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G562R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S179* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | D388H | Missense | 1 |
| LUAD | Lung adenocarcinoma | G462E | Missense | 1 |
| LUAD | Lung adenocarcinoma | G600V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L346L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R448G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L308L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L382L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S527S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P426L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A583T | Missense | 1 |
| READ | Rectum adenocarcinoma | L111F | Missense | 1 |
| SARC | Sarcoma | A570T | Missense | 1 |
| SARC | Sarcoma | E244D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I552I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K560K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M339I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M514I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R538C | Missense | 1 |
| STAD | Stomach adenocarcinoma | A378A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A533V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E254E | Silent | 1 |
| STAD | Stomach adenocarcinoma | G286D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G286S | Missense | 1 |
| STAD | Stomach adenocarcinoma | K581N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L151F | Missense | 1 |
| STAD | Stomach adenocarcinoma | P141S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R210H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R518W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R585H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y535Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A603V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G215G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K177N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M339V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S527L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T193T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y230Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.5 | 4.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 14.3 | 4.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.5 | 8.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.8 | 8.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 6.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 4.8 | 2.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 100 |
| LUAD | Lung adenocarcinoma | 533 | 4.8 | 8.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 14.3 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 4.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.5 | 6.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 14.3 | 19.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.3 | 8.7 | 0 |