Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D283D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E618Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H352D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L481L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q366H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q548* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R324Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S123Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S358F | Missense | 1 |
| BRCA | Breast invasive carcinoma | E600K | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q333K | Missense | 1 |
| BRCA | Breast invasive carcinoma | R368Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R614R | Silent | 1 |
| BRCA | Breast invasive carcinoma | T349T | Silent | 1 |
| CESC | Cervical and endocervical cancers | E5Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | H161Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | H183Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E348* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | P197P | Silent | 1 |
| COAD | Colon adenocarcinoma | R128H | Missense | 1 |
| COAD | Colon adenocarcinoma | R610C | Missense | 1 |
| ESCA | Esophageal carcinoma | G285E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I60I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S460F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I147M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L342F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L343L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | N11D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R144* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | D313H | Missense | 1 |
| LUAD | Lung adenocarcinoma | H352R | Missense | 1 |
| LUAD | Lung adenocarcinoma | I252I | Silent | 1 |
| LUAD | Lung adenocarcinoma | M482I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P195P | Silent | 1 |
| LUAD | Lung adenocarcinoma | S533C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C332W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R77Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D525H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P197P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L172S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L386L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q409* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R301W | Missense | 1 |
| READ | Rectum adenocarcinoma | R380* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | H183Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P581L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R380* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S132S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A508T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A620T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D149D | Silent | 1 |
| STAD | Stomach adenocarcinoma | K587* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Q548R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R137H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S299C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S90N | Missense | 1 |
| STAD | Stomach adenocarcinoma | V74G | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y219C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L511L | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | V291I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A215A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q599H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R368* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R565R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S55L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.5 | 14.6 | 12.5 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 7.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 7.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.2 | 4.9 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 2.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 6.2 | 7.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 12.5 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 12.5 | 9.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 6.2 | 2.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 6.2 | 2.4 | 12.5 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.4 | 12.5 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.2 | 4.9 | 12.5 |
| STAD | Stomach adenocarcinoma | 393 | 6.2 | 19.5 | 12.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 6.2 | 2.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 4.9 | 12.5 |