Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LUAD | Lung adenocarcinoma | S404S | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F465F | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R225* | Nonsense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R306* | Nonsense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S213L | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E54K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E937K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E973Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F114F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P993P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R767S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T443P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V822L | Missense | 1 |
| BRCA | Breast invasive carcinoma | D734N | Missense | 1 |
| BRCA | Breast invasive carcinoma | D873G | Missense | 1 |
| BRCA | Breast invasive carcinoma | D954H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D967D | Silent | 1 |
| BRCA | Breast invasive carcinoma | F840L | Missense | 1 |
| BRCA | Breast invasive carcinoma | H326N | Missense | 1 |
| BRCA | Breast invasive carcinoma | K1029N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L455I | Missense | 1 |
| BRCA | Breast invasive carcinoma | M347I | Missense | 1 |
| BRCA | Breast invasive carcinoma | R855T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S87C | Missense | 1 |
| CESC | Cervical and endocervical cancers | E538* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | E787* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | R306* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | R730L | Missense | 1 |
| COAD | Colon adenocarcinoma | D1054G | Missense | 1 |
| COAD | Colon adenocarcinoma | E33* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | I630T | Missense | 1 |
| COAD | Colon adenocarcinoma | P154S | Missense | 1 |
| COAD | Colon adenocarcinoma | P593P | Silent | 1 |
| COAD | Colon adenocarcinoma | S1032S | Silent | 1 |
| COAD | Colon adenocarcinoma | Y818C | Missense | 1 |
| ESCA | Esophageal carcinoma | E577K | Missense | 1 |
| ESCA | Esophageal carcinoma | M533L | Missense | 1 |
| GBM | Glioblastoma multiforme | H759N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D551H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P976L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q190E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R104S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1031C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1058C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L660P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q362Q | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y341N | Missense | 1 |
| LAML | Acute Myeloid Leukemia | K716Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N905N | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R730* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | T938T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P895P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S401C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A157D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A194G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E102Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E202K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G381R | Missense | 1 |
| LUAD | Lung adenocarcinoma | N570S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1009R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S316F | Missense | 1 |
| LUAD | Lung adenocarcinoma | S411S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T64R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N570S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S519L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F38F | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | G201A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G438V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H563R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V295L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V690I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | H530R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L48F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N905N | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Y185C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A429G | Missense | 1 |
| READ | Rectum adenocarcinoma | F465F | Silent | 1 |
| READ | Rectum adenocarcinoma | H1089R | Missense | 1 |
| READ | Rectum adenocarcinoma | H510N | Missense | 1 |
| READ | Rectum adenocarcinoma | I903I | Silent | 1 |
| READ | Rectum adenocarcinoma | S997Y | Missense | 1 |
| SARC | Sarcoma | P410S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A583A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D117D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F465F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L623F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P73S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R216L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y165N | Missense | 1 |
| STAD | Stomach adenocarcinoma | A193S | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1005Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | D906N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D967D | Silent | 1 |
| STAD | Stomach adenocarcinoma | H686P | Missense | 1 |
| STAD | Stomach adenocarcinoma | I22I | Silent | 1 |
| STAD | Stomach adenocarcinoma | I484M | Missense | 1 |
| STAD | Stomach adenocarcinoma | I786L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R246C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R264R | Silent | 1 |
| STAD | Stomach adenocarcinoma | T782I | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y166C | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y493C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G821G | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Y581* | Nonsense | 1 |
| THCA | Thyroid carcinoma | P263P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A858V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1074V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G344S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H940N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L176I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L732Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P284P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R532W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R813C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1003S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T622I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.1 | 7.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.6 | 12 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.2 | 30 |
| COAD | Colon adenocarcinoma | 367 | 7.1 | 4.8 | 10 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 7.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.6 | 2.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1.2 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.1 | 0 | 10 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.6 | 1.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 10.7 | 10.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.6 | 6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.6 | 3.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.1 | 3.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 10.7 | 4.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 10.7 | 12 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.6 | 0 | 10 |
| THCA | Thyroid carcinoma | 495 | 3.6 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.3 | 13.3 | 40 |