Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | E156K | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | R171S | Missense | 2 |
| LUSC | Lung squamous cell carcinoma | R131G | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | L62L | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | F159F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | T79T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Y31Y | Silent | 1 |
| COAD | Colon adenocarcinoma | A121T | Missense | 1 |
| COAD | Colon adenocarcinoma | A132T | Missense | 1 |
| COAD | Colon adenocarcinoma | D71E | Missense | 1 |
| COAD | Colon adenocarcinoma | L180I | Missense | 1 |
| COAD | Colon adenocarcinoma | N53N | Silent | 1 |
| COAD | Colon adenocarcinoma | R157I | Missense | 1 |
| COAD | Colon adenocarcinoma | R19C | Missense | 1 |
| COAD | Colon adenocarcinoma | R77R | Silent | 1 |
| ESCA | Esophageal carcinoma | A192T | Missense | 1 |
| ESCA | Esophageal carcinoma | K10N | Missense | 1 |
| ESCA | Esophageal carcinoma | R119H | Missense | 1 |
| GBM | Glioblastoma multiforme | R36H | Missense | 1 |
| GBM | Glioblastoma multiforme | V78I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H130Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S66L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A137T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R99* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | L29R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R35W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S38S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A192S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R178C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S41S | Silent | 1 |
| LUAD | Lung adenocarcinoma | W80C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I65I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A111T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S66S | Silent | 1 |
| READ | Rectum adenocarcinoma | A111V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G100G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G54S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L180F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R171C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S169L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S66L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W84* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | C147* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R127W | Missense | 1 |
| STAD | Stomach adenocarcinoma | V78I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A111A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C90C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D96Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E156K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K142E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R127Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 21.4 | 5.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 14.3 | 15.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 7.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 5.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 5.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.6 | 33.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.1 | 5.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.1 | 7.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.1 | 5.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.1 | 2.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 21.4 | 20.5 | 33.3 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 5.1 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.3 | 10.3 | 0 |