Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | P202L | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A250A | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | N179S | Missense | 1 |
| BRCA | Breast invasive carcinoma | D240N | Missense | 1 |
| CESC | Cervical and endocervical cancers | R258Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | V99V | Silent | 1 |
| COAD | Colon adenocarcinoma | S187S | Silent | 1 |
| ESCA | Esophageal carcinoma | G12E | Missense | 1 |
| ESCA | Esophageal carcinoma | Q117H | Missense | 1 |
| ESCA | Esophageal carcinoma | R9* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K162N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P69T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R122T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I72I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E248E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N183Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | A250A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D240Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | L244F | Missense | 1 |
| LUAD | Lung adenocarcinoma | R74R | Silent | 1 |
| LUAD | Lung adenocarcinoma | V77V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E167Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V188V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E267V | Missense | 1 |
| STAD | Stomach adenocarcinoma | F56L | Missense | 1 |
| STAD | Stomach adenocarcinoma | I80I | Silent | 1 |
| STAD | Stomach adenocarcinoma | R159C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R164H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K4N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R213C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R275Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R64H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T214I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 4.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 9.1 | 4.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.1 | 0 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 8.7 | 100 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 13 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 9.1 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 9.1 | 4.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 27.3 | 8.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 9.1 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 13 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.1 | 13 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.2 | 21.7 | 0 |