Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | I42I | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | R154R | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | L32I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N65D | Missense | 1 |
| BRCA | Breast invasive carcinoma | D133E | Missense | 1 |
| BRCA | Breast invasive carcinoma | L193L | Silent | 1 |
| BRCA | Breast invasive carcinoma | T71M | Missense | 1 |
| CESC | Cervical and endocervical cancers | W235* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A146T | Missense | 1 |
| COAD | Colon adenocarcinoma | E41K | Missense | 1 |
| COAD | Colon adenocarcinoma | R118W | Missense | 1 |
| COAD | Colon adenocarcinoma | R236R | Silent | 1 |
| COAD | Colon adenocarcinoma | V116I | Missense | 1 |
| COAD | Colon adenocarcinoma | W90* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Y178Y | Silent | 1 |
| ESCA | Esophageal carcinoma | D24N | Missense | 1 |
| ESCA | Esophageal carcinoma | H183Q | Missense | 1 |
| GBM | Glioblastoma multiforme | I185V | Missense | 1 |
| GBM | Glioblastoma multiforme | R48Q | Missense | 1 |
| GBM | Glioblastoma multiforme | V25I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E4K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I229T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T9T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P20H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T85I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V157L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S83P | Missense | 1 |
| LUAD | Lung adenocarcinoma | I18I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L180L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R128Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y40Y | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L134F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L177L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | N57D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P171T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R154S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R33C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R74T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E41K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L32I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S89P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T217M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A117T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E19K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E35E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I18I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M144I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T217T | Silent | 1 |
| STAD | Stomach adenocarcinoma | L39F | Missense | 1 |
| STAD | Stomach adenocarcinoma | R52* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S232Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | T71M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V116I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A36A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C213G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D75Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F156S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L131I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M80T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P231H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R33C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 4.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 6.2 | 4.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 33.3 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 9.1 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 6.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 2.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 6.2 | 2.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 18.8 | 2.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.2 | 13.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 6.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 43.8 | 6.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 9.1 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.2 | 15.9 | 0 |