Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | E548E | Silent | 3 |
| COAD | Colon adenocarcinoma | N1102N | Silent | 2 |
| COAD | Colon adenocarcinoma | W935* | Nonsense | 2 |
| COAD | Colon adenocarcinoma | W935R | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R822C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A1288T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1199N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D160N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D504H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E163K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E460K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E460Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E522* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E950K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E974K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E976D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E983Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I169T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1166N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V602V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D913H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E298G | Missense | 1 |
| BRCA | Breast invasive carcinoma | E791K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E975G | Missense | 1 |
| BRCA | Breast invasive carcinoma | K938Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1236V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q932E | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1018* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S1048* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S656C | Missense | 1 |
| CESC | Cervical and endocervical cancers | D1203H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E250Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E26K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E425Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E796* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A590D | Missense | 1 |
| COAD | Colon adenocarcinoma | D993D | Silent | 1 |
| COAD | Colon adenocarcinoma | E477A | Missense | 1 |
| COAD | Colon adenocarcinoma | G580G | Silent | 1 |
| COAD | Colon adenocarcinoma | K937* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | N1021K | Missense | 1 |
| COAD | Colon adenocarcinoma | P956P | Silent | 1 |
| COAD | Colon adenocarcinoma | R103Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R663R | Silent | 1 |
| COAD | Colon adenocarcinoma | S1088L | Missense | 1 |
| COAD | Colon adenocarcinoma | S87S | Silent | 1 |
| ESCA | Esophageal carcinoma | D686H | Missense | 1 |
| ESCA | Esophageal carcinoma | R1263C | Missense | 1 |
| ESCA | Esophageal carcinoma | S1285Y | Missense | 1 |
| ESCA | Esophageal carcinoma | S513S | Silent | 1 |
| ESCA | Esophageal carcinoma | T14S | Missense | 1 |
| GBM | Glioblastoma multiforme | C978Y | Missense | 1 |
| GBM | Glioblastoma multiforme | D913E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1255V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C178C | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E564Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E884* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K533E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K922T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R886T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S710F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | W935* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | F1011I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G334G | Silent | 1 |
| LAML | Acute Myeloid Leukemia | D923V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E546E | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T1046A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V423I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D810G | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1302S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D739N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E303K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E357* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E444E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E598* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E98D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1115G | Silent | 1 |
| LUAD | Lung adenocarcinoma | K634N | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1212T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S857R | Missense | 1 |
| LUAD | Lung adenocarcinoma | V788L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | M1291I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N328K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P956T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R578W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1298* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | S513S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S757L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V982L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K842N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | N1102S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P199P | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | W935* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | D539D | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | D926D | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q585K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y615Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A407T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D95D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | I1069V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P988H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S1159S | Silent | 1 |
| READ | Rectum adenocarcinoma | L1236I | Missense | 1 |
| READ | Rectum adenocarcinoma | L313I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D368N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1268E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E715K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H256Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1243I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1204L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q367R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S899L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T971I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V597V | Silent | 1 |
| STAD | Stomach adenocarcinoma | D1072G | Missense | 1 |
| STAD | Stomach adenocarcinoma | D616N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E425* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | E530K | Missense | 1 |
| STAD | Stomach adenocarcinoma | H44N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K586N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L984P | Missense | 1 |
| STAD | Stomach adenocarcinoma | M587I | Missense | 1 |
| STAD | Stomach adenocarcinoma | N1005K | Missense | 1 |
| STAD | Stomach adenocarcinoma | R166W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R330* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R822H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S713Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | T531T | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | G1076A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V992V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A767T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C568* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D948E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1070* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E438* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E699* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E983* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I1164T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K814T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L889I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N848T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1059R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1259W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R215Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R663W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R822R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R924* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T869T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y181Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.9 | 13 | 4.8 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 8 | 9.5 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4 | 4.8 |
| COAD | Colon adenocarcinoma | 367 | 20.6 | 7 | 14.3 |
| ESCA | Esophageal carcinoma | 185 | 2.9 | 4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.9 | 6 | 4.8 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 4.8 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.9 | 1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.9 | 2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.9 | 8 | 9.5 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.9 | 6 | 4.8 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.9 | 2 | 4.8 |
| PAAD | Pancreatic adenocarcinoma | 126 | 8.8 | 1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.9 | 3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.8 | 6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.8 | 11 | 9.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.9 | 1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 11 | 28.6 |