Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | Q803Q | Silent | 3 |
| COAD | Colon adenocarcinoma | F81L | Missense | 2 |
| COAD | Colon adenocarcinoma | N986N | Silent | 2 |
| COAD | Colon adenocarcinoma | P1322P | Silent | 2 |
| COAD | Colon adenocarcinoma | Q592R | Missense | 2 |
| COAD | Colon adenocarcinoma | R693* | Nonsense | 2 |
| COAD | Colon adenocarcinoma | R786G | Missense | 2 |
| COAD | Colon adenocarcinoma | R786R | Silent | 2 |
| GBM | Glioblastoma multiforme | G610G | Silent | 2 |
| HNSC | Head and Neck squamous cell carcinoma | G610G | Silent | 2 |
| HNSC | Head and Neck squamous cell carcinoma | R693* | Nonsense | 2 |
| READ | Rectum adenocarcinoma | P1322P | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A316V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1526N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D544N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1132K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1228Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E981Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H1008Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1514I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I268S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K564* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | L1421L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L56L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P1062S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q225* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q512* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q588* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q780* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1090T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R143* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R411L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R419K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1169Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1269L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1428S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S444* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S577* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T557T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V1279M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y591* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | A1016V | Missense | 1 |
| BRCA | Breast invasive carcinoma | A939A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D863H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1006K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E537D | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1198V | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1288G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G1336G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G42R | Missense | 1 |
| BRCA | Breast invasive carcinoma | H407R | Missense | 1 |
| BRCA | Breast invasive carcinoma | K440K | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q512* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | R725R | Silent | 1 |
| BRCA | Breast invasive carcinoma | S1079S | Silent | 1 |
| BRCA | Breast invasive carcinoma | S903S | Silent | 1 |
| BRCA | Breast invasive carcinoma | T1186I | Missense | 1 |
| CESC | Cervical and endocervical cancers | E566K | Missense | 1 |
| CESC | Cervical and endocervical cancers | P1331S | Missense | 1 |
| CESC | Cervical and endocervical cancers | S871* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A459T | Missense | 1 |
| COAD | Colon adenocarcinoma | A498S | Missense | 1 |
| COAD | Colon adenocarcinoma | A500A | Silent | 1 |
| COAD | Colon adenocarcinoma | D1127G | Missense | 1 |
| COAD | Colon adenocarcinoma | D799N | Missense | 1 |
| COAD | Colon adenocarcinoma | E1102* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E1228* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E537K | Missense | 1 |
| COAD | Colon adenocarcinoma | E566E | Silent | 1 |
| COAD | Colon adenocarcinoma | G1198G | Silent | 1 |
| COAD | Colon adenocarcinoma | G181R | Missense | 1 |
| COAD | Colon adenocarcinoma | G42* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G452G | Silent | 1 |
| COAD | Colon adenocarcinoma | K1443R | Missense | 1 |
| COAD | Colon adenocarcinoma | L1395L | Silent | 1 |
| COAD | Colon adenocarcinoma | L775L | Silent | 1 |
| COAD | Colon adenocarcinoma | M1050T | Missense | 1 |
| COAD | Colon adenocarcinoma | N811S | Missense | 1 |
| COAD | Colon adenocarcinoma | N986S | Missense | 1 |
| COAD | Colon adenocarcinoma | P1330H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q588R | Missense | 1 |
| COAD | Colon adenocarcinoma | Q592* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Q829* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Q829R | Missense | 1 |
| COAD | Colon adenocarcinoma | R1068L | Missense | 1 |
| COAD | Colon adenocarcinoma | R1068Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1415* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R265H | Missense | 1 |
| COAD | Colon adenocarcinoma | R612M | Missense | 1 |
| COAD | Colon adenocarcinoma | R693L | Missense | 1 |
| COAD | Colon adenocarcinoma | R786I | Missense | 1 |
| COAD | Colon adenocarcinoma | R965* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S1255* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S132S | Silent | 1 |
| COAD | Colon adenocarcinoma | S207G | Missense | 1 |
| COAD | Colon adenocarcinoma | S795S | Silent | 1 |
| COAD | Colon adenocarcinoma | S846R | Missense | 1 |
| COAD | Colon adenocarcinoma | S892A | Missense | 1 |
| COAD | Colon adenocarcinoma | W796L | Missense | 1 |
| ESCA | Esophageal carcinoma | D1293N | Missense | 1 |
| ESCA | Esophageal carcinoma | I217V | Missense | 1 |
| ESCA | Esophageal carcinoma | I579F | Missense | 1 |
| ESCA | Esophageal carcinoma | M29T | Missense | 1 |
| ESCA | Esophageal carcinoma | P1330H | Missense | 1 |
| ESCA | Esophageal carcinoma | P474P | Silent | 1 |
| ESCA | Esophageal carcinoma | Q780K | Missense | 1 |
| ESCA | Esophageal carcinoma | R302L | Missense | 1 |
| ESCA | Esophageal carcinoma | R693* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | S1275P | Missense | 1 |
| ESCA | Esophageal carcinoma | T82M | Missense | 1 |
| ESCA | Esophageal carcinoma | V1405V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A317A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1006* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E22K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E480K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E923Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K888R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L461L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R625Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R881T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1391C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W898* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E997* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P1322P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1541T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S91C | Missense | 1 |
| LAML | Acute Myeloid Leukemia | Q733* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R1415* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | D864D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | K44Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S191S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T822A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E122E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E566* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | G1397G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L1170L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N1036S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S501P | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1468S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A316A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D544H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1228K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E429G | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1145C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1164* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G434V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G645G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G650D | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1421F | Missense | 1 |
| LUAD | Lung adenocarcinoma | L476L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L724L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P698P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1438H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R545P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R965P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S135Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | S191S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T118T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A1312S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A530E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A54S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D1211E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F286F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G679* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | L691L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L896L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1117L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1115G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S441F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T736T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V1367I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A1312V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E185E | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | F81F | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | H918H | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | D521N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G1299D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1073H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1071A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A420A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G1520S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G610G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | L1413V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P698P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R411C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1072I | Missense | 1 |
| READ | Rectum adenocarcinoma | D1127G | Missense | 1 |
| READ | Rectum adenocarcinoma | F354L | Missense | 1 |
| READ | Rectum adenocarcinoma | G610S | Missense | 1 |
| READ | Rectum adenocarcinoma | K1034E | Missense | 1 |
| READ | Rectum adenocarcinoma | N986N | Silent | 1 |
| READ | Rectum adenocarcinoma | R321W | Missense | 1 |
| READ | Rectum adenocarcinoma | R786G | Missense | 1 |
| READ | Rectum adenocarcinoma | S132S | Silent | 1 |
| READ | Rectum adenocarcinoma | W1065* | Nonsense | 1 |
| SARC | Sarcoma | A611T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1382A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1175K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K1174K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L145F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1334L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1392L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P567L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P840S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1073L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1133S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1281S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S132L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1344F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1344S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S203F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S526F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S526S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S958L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A627V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1004N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E484D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F1373F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G828G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G867G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K162E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1467I | Missense | 1 |
| STAD | Stomach adenocarcinoma | L56I | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1414P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P570P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P900S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P902S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1068Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R265C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R293G | Missense | 1 |
| STAD | Stomach adenocarcinoma | R302C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R545H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R549H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R620H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S207G | Missense | 1 |
| STAD | Stomach adenocarcinoma | T601T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T794T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V807I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C193Y | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L371F | Missense | 1 |
| THCA | Thyroid carcinoma | C872C | Silent | 1 |
| THCA | Thyroid carcinoma | G1299D | Missense | 1 |
| THCA | Thyroid carcinoma | G742G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D475N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D864D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1228* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E865K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G644G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G660D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I268I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K163T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1360S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P494S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1491* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1247C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1273H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R143* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R244H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1209N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S120N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T82T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1246D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1471M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6 | 9.6 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 5.1 | 2.8 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.3 | 2.8 |
| COAD | Colon adenocarcinoma | 367 | 20.2 | 18.6 | 27.8 |
| ESCA | Esophageal carcinoma | 185 | 2.4 | 5.8 | 2.8 |
| GBM | Glioblastoma multiforme | 283 | 2.4 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.8 | 4.5 | 11.1 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.2 | 1.3 | 2.8 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 5.6 |
| LGG | Brain Lower Grade Glioma | 516 | 2.4 | 1.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.6 | 1.3 | 2.8 |
| LUAD | Lung adenocarcinoma | 533 | 8.3 | 7.7 | 2.8 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.8 | 5.1 | 2.8 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.6 | 0.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 4.8 | 2.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 4.8 | 3.8 | 2.8 |
| SARC | Sarcoma | 247 | 0 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.1 | 7.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 8.3 | 10.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.3 | 0 |
| THCA | Thyroid carcinoma | 495 | 2.4 | 0.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 4.8 | 8.3 | 8.3 |