Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | D352G | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E93Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V197V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D436N | Missense | 1 |
| BRCA | Breast invasive carcinoma | F75L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q158H | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q501K | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q393* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | R361Q | Missense | 1 |
| COAD | Colon adenocarcinoma | D352Y | Missense | 1 |
| COAD | Colon adenocarcinoma | P312L | Missense | 1 |
| COAD | Colon adenocarcinoma | S456L | Missense | 1 |
| COAD | Colon adenocarcinoma | T466T | Silent | 1 |
| COAD | Colon adenocarcinoma | V258F | Missense | 1 |
| COAD | Colon adenocarcinoma | V44V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P326S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P334A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N403T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q499L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A481V | Missense | 1 |
| LUAD | Lung adenocarcinoma | D293N | Missense | 1 |
| LUAD | Lung adenocarcinoma | D436D | Silent | 1 |
| LUAD | Lung adenocarcinoma | K296E | Missense | 1 |
| LUAD | Lung adenocarcinoma | P172P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P70S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q186* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S321F | Missense | 1 |
| LUAD | Lung adenocarcinoma | T160T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T339A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A230S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E308Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T478S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D293H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G83D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A471V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N8I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R304S | Missense | 1 |
| READ | Rectum adenocarcinoma | D350Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G260E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H41Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K416K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P288S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R363K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S310F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S438L | Missense | 1 |
| STAD | Stomach adenocarcinoma | H45N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L315* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S272S | Silent | 1 |
| STAD | Stomach adenocarcinoma | W17* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | S203S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | T193N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A244T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A29S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E81* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P267S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q453H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R206M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R311* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S9Y | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.1 | 2.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 8.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.2 | 16.7 |
| COAD | Colon adenocarcinoma | 367 | 22.2 | 13.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 2.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 33.3 | 13.3 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 6.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 6.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.1 | 13.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.1 | 2.2 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 11.1 | 2.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 13.3 | 33.3 |