Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D537H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E502K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q155* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R339T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R891H | Missense | 1 |
| BRCA | Breast invasive carcinoma | A200V | Missense | 1 |
| BRCA | Breast invasive carcinoma | C639S | Missense | 1 |
| BRCA | Breast invasive carcinoma | D537H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E100K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P418P | Silent | 1 |
| BRCA | Breast invasive carcinoma | S216S | Silent | 1 |
| BRCA | Breast invasive carcinoma | W540G | Missense | 1 |
| CESC | Cervical and endocervical cancers | Y534D | Missense | 1 |
| COAD | Colon adenocarcinoma | A634V | Missense | 1 |
| COAD | Colon adenocarcinoma | D324D | Silent | 1 |
| COAD | Colon adenocarcinoma | E124K | Missense | 1 |
| COAD | Colon adenocarcinoma | P176P | Silent | 1 |
| COAD | Colon adenocarcinoma | P416P | Silent | 1 |
| COAD | Colon adenocarcinoma | R205H | Missense | 1 |
| COAD | Colon adenocarcinoma | R527Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S617S | Silent | 1 |
| COAD | Colon adenocarcinoma | S696S | Silent | 1 |
| COAD | Colon adenocarcinoma | S730F | Missense | 1 |
| COAD | Colon adenocarcinoma | T781T | Silent | 1 |
| COAD | Colon adenocarcinoma | W95* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | W95L | Missense | 1 |
| GBM | Glioblastoma multiforme | G66G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A627A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D383H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E111K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K852K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P516L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V862V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G137R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q693K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L481Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q423* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | T421M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E502D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R412W | Missense | 1 |
| LUAD | Lung adenocarcinoma | A634A | Silent | 1 |
| LUAD | Lung adenocarcinoma | G743A | Missense | 1 |
| LUAD | Lung adenocarcinoma | H824L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P247P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P418S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G197A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H415L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P712P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q155* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | S294P | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H772R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A179V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A631V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P408P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P414P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S753F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E80E | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S719S | Silent | 1 |
| READ | Rectum adenocarcinoma | P585P | Silent | 1 |
| READ | Rectum adenocarcinoma | V862M | Missense | 1 |
| SARC | Sarcoma | H579Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G633V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P414P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S173F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S284F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S435F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S435S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S647S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S664S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S665S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T354T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T781T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V375V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V441V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A74T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C589R | Missense | 1 |
| STAD | Stomach adenocarcinoma | D152N | Missense | 1 |
| STAD | Stomach adenocarcinoma | G495G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G834R | Missense | 1 |
| STAD | Stomach adenocarcinoma | H426Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | L490S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P105P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P176P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P425P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R681T | Missense | 1 |
| STAD | Stomach adenocarcinoma | R707H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S184S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T299N | Missense | 1 |
| STAD | Stomach adenocarcinoma | V604I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A374S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A634V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A767V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C545C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G457G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G820C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I350T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N328K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S503Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T421M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y746Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 6.8 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 5.4 | 8.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.2 | 8.5 | 25 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.7 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.1 | 5.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.4 | 25 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.4 | 5.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.7 | 5.1 | 25 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 5.4 | 5.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.4 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.7 | 1.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 24.3 | 6.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.5 | 16.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.1 | 13.6 | 0 |