Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | A635V | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E237Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H484Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I812I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1027* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V1067V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V133V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E1008E | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q491R | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1103W | Missense | 1 |
| CESC | Cervical and endocervical cancers | S711F | Missense | 1 |
| COAD | Colon adenocarcinoma | E421K | Missense | 1 |
| COAD | Colon adenocarcinoma | G258G | Silent | 1 |
| COAD | Colon adenocarcinoma | M955V | Missense | 1 |
| COAD | Colon adenocarcinoma | P586P | Silent | 1 |
| COAD | Colon adenocarcinoma | P657P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q887R | Missense | 1 |
| ESCA | Esophageal carcinoma | P681A | Missense | 1 |
| ESCA | Esophageal carcinoma | Q205Q | Silent | 1 |
| ESCA | Esophageal carcinoma | T102K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1112K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P429P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T810T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A257T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R513L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N419K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P517H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R393R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E999E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G919R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P688S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T559I | Missense | 1 |
| LUAD | Lung adenocarcinoma | G119V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I834I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1043L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L290L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L479L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P688A | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q246H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q449Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | S412C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T1007T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E1083K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G773W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G885W | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T307T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R786* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | A304V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P271H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q887H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R296H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | W1010* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | G714D | Missense | 1 |
| SARC | Sarcoma | R353* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | A535D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A935A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L333L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L757F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P115S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P204L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P207L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P453L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P496S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P630P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P681L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q409R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1030R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1087W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R786* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1044S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1086S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S272S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S412S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S99Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | A35T | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1112* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | G735R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L280P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L866V | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1014F | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A1041V | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A427A | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | L643P | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q651K | Missense | 1 |
| THYM | Thymoma | T813M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G684G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M37I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1034P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1087Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R513R | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.7 | 3.7 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 3.2 | 1.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.7 | 5.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.2 | 3.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.5 | 1.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 3.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 5.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 19.4 | 7.4 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 5.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.2 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 16.7 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 7.4 | 16.7 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 16.7 |
| SKCM | Skin Cutaneous Melanoma | 290 | 25.8 | 20.4 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 9.3 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.2 | 5.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 1.9 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.7 | 7.4 | 0 |