Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | F2168F | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D1935H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1156K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1442E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F2473L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1947S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1874I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1579L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M801I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1956E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S499F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V184M | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1285E | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1494Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G2480D | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1322R | Silent | 1 |
| BRCA | Breast invasive carcinoma | R2259W | Missense | 1 |
| CESC | Cervical and endocervical cancers | D690N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E223Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E412K | Missense | 1 |
| CESC | Cervical and endocervical cancers | K1530N | Missense | 1 |
| CESC | Cervical and endocervical cancers | S855Y | Missense | 1 |
| COAD | Colon adenocarcinoma | A1504A | Silent | 1 |
| COAD | Colon adenocarcinoma | A446A | Silent | 1 |
| COAD | Colon adenocarcinoma | A625V | Missense | 1 |
| COAD | Colon adenocarcinoma | C262Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E1037V | Missense | 1 |
| COAD | Colon adenocarcinoma | F783F | Silent | 1 |
| COAD | Colon adenocarcinoma | G1118E | Missense | 1 |
| COAD | Colon adenocarcinoma | G1726G | Silent | 1 |
| COAD | Colon adenocarcinoma | G2127S | Missense | 1 |
| COAD | Colon adenocarcinoma | P987T | Missense | 1 |
| COAD | Colon adenocarcinoma | R1804W | Missense | 1 |
| COAD | Colon adenocarcinoma | R1880Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R2201Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S2407S | Silent | 1 |
| COAD | Colon adenocarcinoma | S2436S | Silent | 1 |
| COAD | Colon adenocarcinoma | T1470T | Silent | 1 |
| COAD | Colon adenocarcinoma | T2400T | Silent | 1 |
| ESCA | Esophageal carcinoma | A1023V | Missense | 1 |
| ESCA | Esophageal carcinoma | A240V | Missense | 1 |
| ESCA | Esophageal carcinoma | G230D | Missense | 1 |
| ESCA | Esophageal carcinoma | G2401V | Missense | 1 |
| ESCA | Esophageal carcinoma | R711W | Missense | 1 |
| GBM | Glioblastoma multiforme | L919L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1361A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A660A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1836Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E2136K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E599K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H2142N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H424H | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P2034S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P511S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R226K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y1962C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1926E | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | E451V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L1654L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A410T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R685H | Missense | 1 |
| LUAD | Lung adenocarcinoma | A2100V | Missense | 1 |
| LUAD | Lung adenocarcinoma | K565N | Missense | 1 |
| LUAD | Lung adenocarcinoma | P511P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P536S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P849A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P861L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1445R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1871L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S207C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T1470T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T498A | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1651V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V1822L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A2542V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1854K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1222S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T393A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F1829F | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q2562H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D432N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G851D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G906D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P1281H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1035A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A131T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G246S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S486S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | V416M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y1895Y | Silent | 1 |
| READ | Rectum adenocarcinoma | A2304A | Silent | 1 |
| READ | Rectum adenocarcinoma | R385W | Missense | 1 |
| SARC | Sarcoma | P1963L | Missense | 1 |
| SARC | Sarcoma | R1454W | Missense | 1 |
| SARC | Sarcoma | V856M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A2155A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1125* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | F134F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F181F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I1380I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L219L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L471F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L569L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1083L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1091P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P2263L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P2459P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P476S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P484S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P532L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P532S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P626L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P819L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P861P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1450Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1940F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S2315F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S568F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1089I | Missense | 1 |
| STAD | Stomach adenocarcinoma | A2225V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A886T | Missense | 1 |
| STAD | Stomach adenocarcinoma | I2506V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P626L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R2566C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A1314T | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A1521T | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | E756D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G203C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T1046M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1493V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F2422F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F494F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1303G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G537E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L2357L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1210L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P2012P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P511L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P887P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1316Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q951R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1182* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1824C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2185W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2497W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S2113I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T133T | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.5 | 8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.2 | 4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 17.4 | 9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.2 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.5 | 8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.3 | 1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.7 | 9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.2 | 1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.5 | 3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.2 | 1 | 0 |
| SARC | Sarcoma | 247 | 0 | 3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.9 | 14 | 50 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 5 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 17.4 | 9 | 50 |