Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| CESC | Cervical and endocervical cancers | Q277* | Nonsense | 2 |
| COAD | Colon adenocarcinoma | K658R | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A140T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D184A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D184N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D225H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D663H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D663N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E148K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E182K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I557M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K656N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L183L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L452L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P338S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q272* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | E566K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G431S | Missense | 1 |
| BRCA | Breast invasive carcinoma | I214M | Missense | 1 |
| CESC | Cervical and endocervical cancers | S438* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | S460* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | K658K | Silent | 1 |
| COAD | Colon adenocarcinoma | L186L | Silent | 1 |
| COAD | Colon adenocarcinoma | N299S | Missense | 1 |
| COAD | Colon adenocarcinoma | N446N | Silent | 1 |
| COAD | Colon adenocarcinoma | Q253K | Missense | 1 |
| COAD | Colon adenocarcinoma | Q272* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R207W | Missense | 1 |
| COAD | Colon adenocarcinoma | R385* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R512C | Missense | 1 |
| COAD | Colon adenocarcinoma | R718W | Missense | 1 |
| COAD | Colon adenocarcinoma | V603V | Silent | 1 |
| COAD | Colon adenocarcinoma | W196* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Y394Y | Silent | 1 |
| ESCA | Esophageal carcinoma | S325S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A138T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I586L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y627Y | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A145G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E402* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F170C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F170V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G128* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G312G | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | K626* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N229H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q156* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q253* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q267* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S279* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S460* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y627* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A145A | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A323S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A502P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I271T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P370H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V439L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A316A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | F170V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H169Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K711* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | L539Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q156* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q253* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q280* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q456* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | W196G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | W202L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G340S | Missense | 1 |
| LUAD | Lung adenocarcinoma | L622M | Missense | 1 |
| LUAD | Lung adenocarcinoma | L632P | Missense | 1 |
| LUAD | Lung adenocarcinoma | P621P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R179W | Missense | 1 |
| LUAD | Lung adenocarcinoma | S460* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R227H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R227C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A321T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L463L | Silent | 1 |
| READ | Rectum adenocarcinoma | K658R | Missense | 1 |
| READ | Rectum adenocarcinoma | R717W | Missense | 1 |
| SARC | Sarcoma | D376D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A323A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L416F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P629S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S143N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L245P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L294L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L334L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P175H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P190H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q267Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | R163Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R551H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R700Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T613T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V541G | Missense | 1 |
| STAD | Stomach adenocarcinoma | V604M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y546H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A496T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A648A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D399N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G619D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L357M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M211V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R548C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R700Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T495M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V409A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V603V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.1 | 16.4 | 4.3 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 17.4 |
| COAD | Colon adenocarcinoma | 367 | 22.7 | 10.4 | 13 |
| ESCA | Esophageal carcinoma | 185 | 4.5 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.5 | 3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.5 | 6 | 39.1 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 4.5 | 7.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.5 | 7.5 | 21.7 |
| LUAD | Lung adenocarcinoma | 533 | 4.5 | 6 | 4.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 4.5 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3 | 0 |
| SARC | Sarcoma | 247 | 4.5 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 4.5 | 4.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 18.2 | 13.4 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 13.4 | 0 |