Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | P82P | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | R590C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1220H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1227Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1444Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I125I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1455F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1455L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L625L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P883S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q968* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1406T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1423Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V238I | Missense | 1 |
| BRCA | Breast invasive carcinoma | C47C | Silent | 1 |
| BRCA | Breast invasive carcinoma | D950H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E732K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E788K | Missense | 1 |
| BRCA | Breast invasive carcinoma | K338N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L922* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | M1082V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q12Q | Silent | 1 |
| BRCA | Breast invasive carcinoma | S1012T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1390F | Missense | 1 |
| BRCA | Breast invasive carcinoma | V1073V | Silent | 1 |
| BRCA | Breast invasive carcinoma | V416V | Silent | 1 |
| BRCA | Breast invasive carcinoma | V462L | Missense | 1 |
| CESC | Cervical and endocervical cancers | R980T | Missense | 1 |
| COAD | Colon adenocarcinoma | A562A | Silent | 1 |
| COAD | Colon adenocarcinoma | E1255L | Missense | 1 |
| COAD | Colon adenocarcinoma | K250T | Missense | 1 |
| COAD | Colon adenocarcinoma | L1352F | Missense | 1 |
| COAD | Colon adenocarcinoma | P421S | Missense | 1 |
| COAD | Colon adenocarcinoma | P966S | Missense | 1 |
| COAD | Colon adenocarcinoma | R100H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1179* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1428* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1480C | Missense | 1 |
| COAD | Colon adenocarcinoma | R43Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S164G | Missense | 1 |
| COAD | Colon adenocarcinoma | S869F | Missense | 1 |
| COAD | Colon adenocarcinoma | S99L | Missense | 1 |
| COAD | Colon adenocarcinoma | V56A | Missense | 1 |
| ESCA | Esophageal carcinoma | L596I | Missense | 1 |
| GBM | Glioblastoma multiforme | R115Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F25L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L627L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q483* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R935H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V416V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V1000V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1179Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K1456K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L542L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L90L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R276G | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1149A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D1449N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E472K | Missense | 1 |
| LUAD | Lung adenocarcinoma | I998M | Missense | 1 |
| LUAD | Lung adenocarcinoma | K385E | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1089L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R43G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R959T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S961Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | T630S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D1137H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D443H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E467K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G1431K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H284R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K208K | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L1084L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | N1365S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1099A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1375L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P398H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S169* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E71V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F442S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q1440Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R807R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | V1537I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | W530* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | L1182F | Missense | 1 |
| READ | Rectum adenocarcinoma | L474I | Missense | 1 |
| READ | Rectum adenocarcinoma | S164S | Silent | 1 |
| SARC | Sarcoma | E1256Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A997V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C621W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H1174Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K318R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L620L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L823F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1372S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P411S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P449S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P594L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1480C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T248T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V1463V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1149V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D406A | Missense | 1 |
| STAD | Stomach adenocarcinoma | E253* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | H1536H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K380R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q849R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1093W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1285H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1480C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1503L | Missense | 1 |
| STAD | Stomach adenocarcinoma | T248T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T414K | Missense | 1 |
| STAD | Stomach adenocarcinoma | V238V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1345T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C54Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1232G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1251D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1251N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D981Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E159* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E200* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E491* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E920K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F756C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I802I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K310R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L823F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L832I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L983I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N290S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P947P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1480C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1480S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R382H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R668C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R784* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1503S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S99L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T248M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.4 | 8.2 | 8.3 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 8.2 | 8.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.4 | 12.2 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.1 | 2 | 8.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.1 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.1 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 9.4 | 1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.1 | 9.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.2 | 9.2 | 8.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.1 | 2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.1 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1 | 8.3 |
| READ | Rectum adenocarcinoma | 122 | 3.1 | 2 | 0 |
| SARC | Sarcoma | 247 | 0 | 1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.4 | 12.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.4 | 9.2 | 8.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 18.4 | 33.3 |