Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | K799E | Missense | 4 |
| COAD | Colon adenocarcinoma | K799K | Silent | 4 |
| STAD | Stomach adenocarcinoma | R869H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A1114A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D1385N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F923F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | H379Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H383D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1156I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K344K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L641F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1115S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q851* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R519Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1394F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S204L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S621C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1143S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E823* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | E862K | Missense | 1 |
| BRCA | Breast invasive carcinoma | I49N | Missense | 1 |
| BRCA | Breast invasive carcinoma | K131K | Silent | 1 |
| BRCA | Breast invasive carcinoma | L1034V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L262V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q437Q | Silent | 1 |
| BRCA | Breast invasive carcinoma | R492S | Missense | 1 |
| BRCA | Breast invasive carcinoma | R519Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | V1140A | Missense | 1 |
| CESC | Cervical and endocervical cancers | A892V | Missense | 1 |
| CESC | Cervical and endocervical cancers | D819H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E517Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | H220D | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1436V | Missense | 1 |
| CESC | Cervical and endocervical cancers | L342F | Missense | 1 |
| CESC | Cervical and endocervical cancers | L89L | Silent | 1 |
| COAD | Colon adenocarcinoma | A751S | Missense | 1 |
| COAD | Colon adenocarcinoma | C1187R | Missense | 1 |
| COAD | Colon adenocarcinoma | E800* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G601G | Silent | 1 |
| COAD | Colon adenocarcinoma | H1033H | Silent | 1 |
| COAD | Colon adenocarcinoma | H1033N | Missense | 1 |
| COAD | Colon adenocarcinoma | H1033Y | Missense | 1 |
| COAD | Colon adenocarcinoma | K281T | Missense | 1 |
| COAD | Colon adenocarcinoma | K578K | Silent | 1 |
| COAD | Colon adenocarcinoma | L412L | Silent | 1 |
| COAD | Colon adenocarcinoma | L428P | Missense | 1 |
| COAD | Colon adenocarcinoma | L683L | Silent | 1 |
| COAD | Colon adenocarcinoma | R1304H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1340R | Silent | 1 |
| COAD | Colon adenocarcinoma | R199Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R263* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R899H | Missense | 1 |
| COAD | Colon adenocarcinoma | R899R | Silent | 1 |
| COAD | Colon adenocarcinoma | R955H | Missense | 1 |
| COAD | Colon adenocarcinoma | S374S | Silent | 1 |
| COAD | Colon adenocarcinoma | S493S | Silent | 1 |
| COAD | Colon adenocarcinoma | S916L | Missense | 1 |
| COAD | Colon adenocarcinoma | T605M | Missense | 1 |
| COAD | Colon adenocarcinoma | V977I | Missense | 1 |
| ESCA | Esophageal carcinoma | A1472A | Silent | 1 |
| ESCA | Esophageal carcinoma | E1125E | Silent | 1 |
| ESCA | Esophageal carcinoma | L1109L | Silent | 1 |
| ESCA | Esophageal carcinoma | S500S | Silent | 1 |
| GBM | Glioblastoma multiforme | I384F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A883S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1290G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H1210L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q168E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1157W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1479* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R594G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L1034V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V353V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | F1112S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G208G | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H930R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q1434E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R48C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R579W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F728F | Silent | 1 |
| LUAD | Lung adenocarcinoma | A73S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D943Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1264E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E364Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E703V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1072A | Missense | 1 |
| LUAD | Lung adenocarcinoma | M372I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q851E | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1281L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R504L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R525C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V236V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D192D | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E1183* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | E690L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L1168L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L757F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | M443V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1339W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R769R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V273V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V783L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H1033R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K216I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K799K | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R899H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N589T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q851K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P599H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R258Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R693W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R697C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R955H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1294F | Missense | 1 |
| READ | Rectum adenocarcinoma | E786G | Missense | 1 |
| READ | Rectum adenocarcinoma | I748F | Missense | 1 |
| READ | Rectum adenocarcinoma | K799E | Missense | 1 |
| READ | Rectum adenocarcinoma | K799K | Silent | 1 |
| READ | Rectum adenocarcinoma | R199Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R899C | Missense | 1 |
| READ | Rectum adenocarcinoma | S916P | Missense | 1 |
| SARC | Sarcoma | A1472A | Silent | 1 |
| SARC | Sarcoma | M299V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1250A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1278A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E517D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1380V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K250N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1352F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1115S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P362P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P362S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P431S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P920Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R513C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1240S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S204L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S98F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V273V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V701V | Silent | 1 |
| STAD | Stomach adenocarcinoma | D665D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E43K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1242D | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1207N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1004L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1363S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P472P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1454H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R504H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R551W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R780Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S398S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T310S | Missense | 1 |
| STAD | Stomach adenocarcinoma | T460A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | S1251S | Silent | 1 |
| THCA | Thyroid carcinoma | E1268E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1228C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C941Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E733D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1466W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I824L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1116K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K319N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K86E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L585L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L659S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N376D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P271H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1056H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1241H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R243C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R573I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S161N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S417F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.7 | 7.3 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 3.8 | 6.5 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 1.9 | 4.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 25 | 13.8 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 7.7 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 1.9 | 4.1 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.9 | 0.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.9 | 2.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 1.9 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.8 | 8.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.7 | 4.1 | 16.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.9 | 2.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.9 | 4.9 | 0 |
| SARC | Sarcoma | 247 | 1.9 | 0.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.5 | 8.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 7.7 | 9.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 1.9 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 1.9 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.8 | 12.2 | 0 |