Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | E405K | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A442S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C385Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G402G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I312I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L325L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L725L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P590P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q35E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R487G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R954L | Missense | 1 |
| BRCA | Breast invasive carcinoma | A476T | Missense | 1 |
| BRCA | Breast invasive carcinoma | E310K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E595* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | G674S | Missense | 1 |
| CESC | Cervical and endocervical cancers | R322W | Missense | 1 |
| CESC | Cervical and endocervical cancers | V216M | Missense | 1 |
| COAD | Colon adenocarcinoma | A870V | Missense | 1 |
| COAD | Colon adenocarcinoma | D531N | Missense | 1 |
| COAD | Colon adenocarcinoma | D949N | Missense | 1 |
| COAD | Colon adenocarcinoma | E1013K | Missense | 1 |
| COAD | Colon adenocarcinoma | E206K | Missense | 1 |
| COAD | Colon adenocarcinoma | N152N | Silent | 1 |
| COAD | Colon adenocarcinoma | P26H | Missense | 1 |
| COAD | Colon adenocarcinoma | R495L | Missense | 1 |
| COAD | Colon adenocarcinoma | R802W | Missense | 1 |
| COAD | Colon adenocarcinoma | R875W | Missense | 1 |
| COAD | Colon adenocarcinoma | T885M | Missense | 1 |
| COAD | Colon adenocarcinoma | V962I | Missense | 1 |
| ESCA | Esophageal carcinoma | A584T | Missense | 1 |
| ESCA | Esophageal carcinoma | H8Y | Missense | 1 |
| ESCA | Esophageal carcinoma | L239L | Silent | 1 |
| ESCA | Esophageal carcinoma | R259C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E629* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R802Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T30M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T389M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E626D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G713S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G780V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y140H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A905T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | C729W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E514D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K283N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N170S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A924T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G780L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R802L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A588A | Silent | 1 |
| LUAD | Lung adenocarcinoma | G1048W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G975R | Missense | 1 |
| LUAD | Lung adenocarcinoma | H108H | Silent | 1 |
| LUAD | Lung adenocarcinoma | R396R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1055I | Missense | 1 |
| LUAD | Lung adenocarcinoma | T565I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y479Y | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A870A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G334G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | K174* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | L703F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P366P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Y649Y | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | N399Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A821T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D726N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1038C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R656H | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A559T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A240T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D775D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | L457S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L65L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | N74D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1038C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R288C | Missense | 1 |
| READ | Rectum adenocarcinoma | A34T | Missense | 1 |
| READ | Rectum adenocarcinoma | R996S | Missense | 1 |
| SARC | Sarcoma | R798S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1031V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A844A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E551K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G254D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G254S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I251I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L751L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L788F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L988L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P129L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P252P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P450S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P590L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P941P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S415N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1051I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1051T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T110M | Missense | 1 |
| STAD | Stomach adenocarcinoma | A147T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A945T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D214D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E167K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E167V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E773K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G489R | Missense | 1 |
| STAD | Stomach adenocarcinoma | I466T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K754R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L117R | Missense | 1 |
| STAD | Stomach adenocarcinoma | P111L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P445P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R259C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R259H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R534H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S422Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | V241M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V404V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V647M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y250H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y33Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y940C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C234C | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | R527W | Missense | 1 |
| THYM | Thymoma | D608Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A383T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C638Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D287N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D598Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E160K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E773K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E813* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M362I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P691P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P781S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R427S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R529Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R737W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R847Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R882Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V647M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V971M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 16.7 | 4.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 1.9 | 25 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 3.3 | 10.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.3 | 2.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 2.8 | 25 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.3 | 3.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 13.3 | 0.9 | 25 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.9 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 4.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0.9 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.3 | 10.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.3 | 17 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.3 | 0.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0.9 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.3 | 16 | 25 |